Comput Math Methods Med - Modelling tumour oxygenation, reoxygenation and implications on treatment outcome.

Tópicos

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Resumo

Oxygenation is an important component of the tumour microenvironment, having a significant impact on the progression and management of cancer. Theoretical determination of tissue oxygenation through simulations of the oxygen transport process is a powerful tool to characterise the spatial distribution of oxygen on the microscopic scale and its dynamics and to study its impact on the response to radiation. Accurate modelling of tumour oxygenation must take into account important aspects that are specific to tumours, making the quantitative characterisation of oxygenation rather difficult. This paper aims to discuss the important aspects of modelling tumour oxygenation, reoxygenation, and implications for treatment.

Resumo Limpo

oxygen import compon tumour microenviron signific impact progress manag cancer theoret determin tissu oxygen simul oxygen transport process power tool characteris spatial distribut oxygen microscop scale dynam studi impact respons radiat accur model tumour oxygen must take account import aspect specif tumour make quantit characteris oxygen rather difficult paper aim discuss import aspect model tumour oxygen reoxygen implic treatment

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