Comput Math Methods Med - Risk factors for mortality among 2009 A/H1N1 influenza hospitalizations in Maricopa County, Arizona, April 2009 to March 2010.

Tópicos

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Resumo

We analyzed individual-level data on pandemic influenza A/H1N1pdm hospitalizations from the enhanced surveillance system of the Maricopa County Department of Public Health, AZ, USA from April 1st, 2009 to March 31st, 2010. We also assessed the the risk of death among A/H1N1 hospitalizations using multivariate logistic regression. Hospitalization rates were significantly higher among Native Americans (risk ratio (RR) = 6.2; 95% CI: 6.15, 6.21), non-Hispanic Black (RR = 3.84; 95% CI: 3.8, 3.9), and Hispanics (RR = 2.0; 95% CI: 2.0, 2.01) compared to non-Hispanic Whites. Throughout the spring, 59.2% of hospitalized patients received antiviral treatment; the proportion of patients treated increased significantly during the fall to 74.4% (Chi-square test, P < 0.0001). In our best-fit logistic model, the adjusted risk of death among A/H1N1 inpatients was significantly higher during the fall wave (August 16, 2009 to March 31, 2010, OR = 3.94; 95% CI: 1.72, 9.03) compared to the spring wave (April 1, 2009 to August 15, 2009). Moreover, chronic lung disease (OR = 3.5; 95% CI: 1.7, 7.4), cancer within the last 12 months (OR = 4.3; 95%CI: 1.3, 14.8), immuno-suppression (OR = 4.0; 95% CI: 1.84, 8.9), and admission delays (OR = 4.6; 95% CI: 2.2, 9.5) were significantly associated with an increased the risk of death among A/H1N1 inpatients.

Resumo Limpo

analyz individuallevel data pandem influenza ahnpdm hospit enhanc surveil system maricopa counti depart public health az usa april st march st also assess risk death among ahn hospit use multivari logist regress hospit rate signific higher among nativ american risk ratio rr ci nonhispan black rr ci hispan rr ci compar nonhispan white throughout spring hospit patient receiv antivir treatment proport patient treat increas signific fall chisquar test p bestfit logist model adjust risk death among ahn inpati signific higher fall wave august march ci compar spring wave april august moreov chronic lung diseas ci cancer within last month ci immunosuppress ci admiss delay ci signific associ increas risk death among ahn inpati

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