Comput Methods Programs Biomed - #NOME?

Tópicos

{ measur(2081) correl(1212) valu(896) }
{ medic(1828) order(1363) alert(1069) }
{ model(3404) distribut(989) bayesian(671) }
{ treatment(1704) effect(941) patient(846) }
{ result(1111) use(1088) new(759) }
{ group(2977) signific(1463) compar(1072) }
{ framework(1458) process(801) describ(734) }
{ care(1570) inform(1187) nurs(1089) }
{ age(1611) year(1155) adult(843) }
{ perform(999) metric(946) measur(919) }
{ cost(1906) reduc(1198) effect(832) }
{ data(1737) use(1416) pattern(1282) }
{ analysi(2126) use(1163) compon(1037) }
{ cancer(2502) breast(956) screen(824) }
{ method(1969) cluster(1462) data(1082) }
{ imag(1057) registr(996) error(939) }
{ data(2317) use(1299) case(1017) }
{ survey(1388) particip(1329) question(1065) }
{ patient(2315) diseas(1263) diabet(1191) }
{ error(1145) method(1030) estim(1020) }
{ concept(1167) ontolog(924) domain(897) }
{ design(1359) user(1324) use(1319) }
{ signal(2180) analysi(812) frequenc(800) }
{ gene(2352) biolog(1181) express(1162) }
{ process(1125) use(805) approach(778) }
{ activ(1452) weight(1219) physic(1104) }
{ can(774) often(719) complex(702) }
{ method(1219) similar(1157) match(930) }
{ imag(2675) segment(2577) method(1081) }
{ take(945) account(800) differ(722) }
{ motion(1329) object(1292) video(1091) }
{ problem(2511) optim(1539) algorithm(950) }
{ chang(1828) time(1643) increas(1301) }
{ model(2220) cell(1177) simul(1124) }
{ search(2224) databas(1162) retriev(909) }
{ studi(1410) differ(1259) use(1210) }
{ model(2341) predict(2261) use(1141) }
{ spatial(1525) area(1432) region(1030) }
{ monitor(1329) mobil(1314) devic(1160) }
{ model(2656) set(1616) predict(1553) }
{ activ(1138) subject(705) human(624) }
{ use(2086) technolog(871) perceiv(783) }
{ health(1844) social(1437) communiti(874) }
{ high(1669) rate(1365) level(1280) }
{ detect(2391) sensit(1101) algorithm(908) }
{ imag(1947) propos(1133) code(1026) }
{ inform(2794) health(2639) internet(1427) }
{ system(1976) rule(880) can(841) }
{ bind(1733) structur(1185) ligand(1036) }
{ sequenc(1873) structur(1644) protein(1328) }
{ featur(3375) classif(2383) classifi(1994) }
{ imag(2830) propos(1344) filter(1198) }
{ network(2748) neural(1063) input(814) }
{ studi(2440) review(1878) systemat(933) }
{ assess(1506) score(1403) qualiti(1306) }
{ surgeri(1148) surgic(1085) robot(1054) }
{ learn(2355) train(1041) set(1003) }
{ clinic(1479) use(1117) guidelin(835) }
{ algorithm(1844) comput(1787) effici(935) }
{ extract(1171) text(1153) clinic(932) }
{ method(1557) propos(1049) approach(1037) }
{ data(1714) softwar(1251) tool(1186) }
{ control(1307) perform(991) simul(935) }
{ general(901) number(790) one(736) }
{ method(984) reconstruct(947) comput(926) }
{ featur(1941) imag(1645) propos(1176) }
{ case(1353) use(1143) diagnosi(1136) }
{ howev(809) still(633) remain(590) }
{ data(3963) clinic(1234) research(1004) }
{ risk(3053) factor(974) diseas(938) }
{ research(1085) discuss(1038) issu(1018) }
{ system(1050) medic(1026) inform(1018) }
{ import(1318) role(1303) understand(862) }
{ visual(1396) interact(850) tool(830) }
{ compound(1573) activ(1297) structur(1058) }
{ perform(1367) use(1326) method(1137) }
{ studi(1119) effect(1106) posit(819) }
{ blood(1257) pressur(1144) flow(957) }
{ record(1888) medic(1808) patient(1693) }
{ health(3367) inform(1360) care(1135) }
{ model(3480) simul(1196) paramet(876) }
{ ehr(2073) health(1662) electron(1139) }
{ state(1844) use(1261) util(961) }
{ research(1218) medic(880) student(794) }
{ patient(2837) hospit(1953) medic(668) }
{ sampl(1606) size(1419) use(1276) }
{ data(3008) multipl(1320) sourc(1022) }
{ first(2504) two(1366) second(1323) }
{ intervent(3218) particip(2042) group(1664) }
{ time(1939) patient(1703) rate(768) }
{ patient(1821) servic(1111) care(1106) }
{ can(981) present(881) function(850) }
{ structur(1116) can(940) graph(676) }
{ use(976) code(926) identifi(902) }
{ use(1733) differ(960) four(931) }
{ drug(1928) target(777) effect(648) }
{ implement(1333) system(1263) develop(1122) }
{ estim(2440) model(1874) function(577) }
{ decis(3086) make(1611) patient(1517) }
{ method(2212) result(1239) propos(1039) }

Resumo

RPOSE: The accuracy of dose delivery and the evaluation of differences between calculated and delivered dose distributions, has been studied by several groups. The aim of this investigation is to extend the gamma index by including radiobiological information and to propose a new index that we will here forth refer to as the gamma plus (+). Furthermore, to validate the robustness of this new index in performing a quality control analysis of an IMRT treatment plan using pure radiobiological measures such as the biologically effective uniform dose (D) and complication-free tumor control probability (P+).MATERIAL AND METHODS: A new quality assurance index, the (+), is proposed based on the theoretical concept of gamma index presented by Low et al. (1998). In this study, the dose difference, including the radiobiological dose information (biological effective dose, BED) is used instead of just the physical dose difference when performing the + calculation. An in-house software was developed to compare different dose distributions based on the + concept. A test pattern for a two-dimensional dose comparison was built using the in-house software platform. The + index was tested using planar dose distributions (exported from the treatment planning system) and delivered (film) dose distributions acquired in a solid water phantom using a test pattern and a theoretical clinical case. Furthermore, a lung cancer case for a patient treated with IMRT was also selected for the analysis. The respective planar dose distributions from the treatment plan and the film were compared based on the + index and were evaluated using the radiobiological measures of P+ and D.RESULTS: The results for the test pattern analysis indicate that the + index distributions differ from those of the gamma index since the former considers radiobiological parameters that may affect treatment outcome. For the theoretical clinical case, it is observed that the + index varies for different treatment parameters (e.g. dose per fraction). The dose area histogram (DAH) from the plan and film dose distributions are associated with P+ values of 50.8% and 49.0%, for a D to the target of 54.0 Gy and 53.3 Gy, respectively.CONCLUSION: The + index shows advantageous properties in the quantitative evaluation of dose delivery and quality control of IMRT treatments because it includes information about the expected responses and radiobiological doses of the individual tissues.

Resumo Limpo

rpose accuraci dose deliveri evalu differ calcul deliv dose distribut studi sever group aim investig extend gamma index includ radiobiolog inform propos new index will forth refer gamma plus furthermor valid robust new index perform qualiti control analysi imrt treatment plan use pure radiobiolog measur biolog effect uniform dose d complicationfre tumor control probabl pmateri method new qualiti assur index propos base theoret concept gamma index present low et al studi dose differ includ radiobiolog dose inform biolog effect dose bed use instead just physic dose differ perform calcul inhous softwar develop compar differ dose distribut base concept test pattern twodimension dose comparison built use inhous softwar platform index test use planar dose distribut export treatment plan system deliv film dose distribut acquir solid water phantom use test pattern theoret clinic case furthermor lung cancer case patient treat imrt also select analysi respect planar dose distribut treatment plan film compar base index evalu use radiobiolog measur p dresult result test pattern analysi indic index distribut differ gamma index sinc former consid radiobiolog paramet may affect treatment outcom theoret clinic case observ index vari differ treatment paramet eg dose per fraction dose area histogram dah plan film dose distribut associ p valu d target gy gy respectivelyconclus index show advantag properti quantit evalu dose deliveri qualiti control imrt treatment includ inform expect respons radiobiolog dose individu tissu

Resumos Similares

Int J Med Inform - Assessment of efficiency and safety of the comprehensive Chemotherapy Assistance Program for ordering oncology medications. ( 0,641149851720722 )
Health Informatics J - Interprofessional, simulation-based technology-enhanced learning to improve physical healthcare in psychiatry: The RAMPPS course. ( 0,623263970795528 )
Comput Methods Programs Biomed - Estimation of the concordance correlation coefficient for repeated measures using SAS and R. ( 0,622548607111371 )
J Clin Monit Comput - Evaluation of the estimated continuous cardiac output monitoring system in adults and children undergoing kidney transplant surgery: a pilot study. ( 0,602537504532516 )
AMIA Annu Symp Proc - A real-time screening alert improves patient recruitment efficiency. ( 0,602201168592393 )
J Clin Monit Comput - Cardiac index measurements by transcutaneous Doppler ultrasound and transthoracic echocardiography in adult and pediatric emergency patients. ( 0,586609934652814 )
J Clin Monit Comput - Validation of indirect calorimetry for measurement of energy expenditure in healthy volunteers undergoing pressure controlled non-invasive ventilation support. ( 0,584610385842777 )
J Med Syst - Automatic quantification of spinal curvature in scoliotic radiograph using image processing. ( 0,576198594558602 )
J Clin Monit Comput - Comparison of ear and chest probes in transcutaneous carbon dioxide pressure measurements during general anesthesia in adults. ( 0,567783583015193 )
J Am Med Inform Assoc - Prescribers' expectations and barriers to electronic prescribing of controlled substances. ( 0,565905910881761 )
J Am Med Inform Assoc - Appropriateness of commercially available and partially customized medication dosing alerts among pediatric patients. ( 0,564350382363657 )
J Am Med Inform Assoc - Collaborative knowledge acquisition for the design of context-aware alert systems. ( 0,564347239899634 )
J Am Med Inform Assoc - Applying human factors principles to alert design increases efficiency and reduces prescribing errors in a scenario-based simulation. ( 0,5614135985519 )
Int J Med Inform - Faxed Arabic prescriptions: a medication error waiting to happen? ( 0,560061420740194 )
J Am Med Inform Assoc - Ability of pharmacy clinical decision-support software to alert users about clinically important drug-drug interactions. ( 0,558816453385864 )
J Clin Monit Comput - Peripheral tissue oximetry: comparing three commercial near-infrared spectroscopy oximeters on the forearm. ( 0,557429052532798 )
Med Decis Making - Evaluation of Physicians' Cognitive Styles. ( 0,556503668810541 )
AMIA Annu Symp Proc - Ontological approach for safe and effective polypharmacy prescription. ( 0,555368397998607 )
J Clin Monit Comput - Comparison of SNAP? II and BIS Vista indices during normothermic cardiopulmonary bypass under isoflurane anesthesia. ( 0,554594079312921 )
Comput. Biol. Med. - Fast generation of T2* maps in the entire range of clinical interest: application to thalassemia major patients. ( 0,554102843040548 )
J Clin Monit Comput - The evaluation of a non-invasive respiratory volume monitor in surgical patients undergoing elective surgery with general anesthesia. ( 0,553902176393797 )
Comput. Aided Surg. - Non-invasive quantification of lower limb mechanical alignment in flexion. ( 0,553859182568034 )
J Clin Monit Comput - Masseter muscle oxygen saturation is associated with central venous oxygen saturation in patients with severe sepsis. ( 0,553300715388664 )
Methods Inf Med - Measuring inter-observer agreement in contour delineation of medical imaging in a dummy run using Fleiss' kappa. ( 0,552663385415343 )
J Am Med Inform Assoc - Evaluating the accuracy of electronic pediatric drug dosing rules. ( 0,55223875638818 )
Med Decis Making - Not simply more of the same: distinguishing between patient heterogeneity and parameter uncertainty. ( 0,54947331679884 )
Appl Clin Inform - Provider use of and attitudes towards an active clinical alert: a case study in decision support. ( 0,548470541655359 )
J Am Med Inform Assoc - The safety of electronic prescribing: manifestations, mechanisms, and rates of system-related errors associated with two commercial systems in hospitals. ( 0,546865760440476 )
J Am Med Inform Assoc - Unrealized potential and residual consequences of electronic prescribing on pharmacy workflow in the outpatient pharmacy. ( 0,544862931037416 )
J Am Med Inform Assoc - Factors contributing to an increase in duplicate medication order errors after CPOE implementation. ( 0,544027174662481 )
AMIA Annu Symp Proc - An analysis and recommendations for multidisciplinary computerized handoff applications in hospitals. ( 0,540406026834119 )
J. Med. Internet Res. - Physician order entry or nurse order entry? Comparison of two implementation strategies for a computerized order entry system aimed at reducing dosing medication errors. ( 0,539468511478655 )
Comput. Biol. Med. - Gait variability and stability measures: minimum number of strides and within-session reliability. ( 0,537738637489242 )
Comput. Biol. Med. - Development and evaluation of an algorithm for computer analysis of maternal heart rate during labor. ( 0,537649428466502 )
J Am Med Inform Assoc - How to improve the delivery of medication alerts within computerized physician order entry systems: an international Delphi study. ( 0,537617223714373 )
J Am Med Inform Assoc - Integrating pharmacogenetic information and clinical decision support into the electronic health record. ( 0,537334408633294 )
Med Biol Eng Comput - Intra-protocol repeatability and inter-protocol agreement for the analysis of scapulo-humeral coordination. ( 0,534707416418073 )
IEEE J Biomed Health Inform - A Bayesian Estimation Framework for Pharmacogenomics Driven Warfarin Dosing: A Comparative Study. ( 0,534671767260548 )
J Am Med Inform Assoc - A clinical data warehouse-based process for refining medication orders alerts. ( 0,534636067099094 )
Comput Methods Programs Biomed - Extracting more information from EEG recordings for a better description of sleep. ( 0,533366017667564 )
Comput Methods Programs Biomed - Ultrasound IMT measurement on a multi-ethnic and multi-institutional database: our review and experience using four fully automated and one semi-automated methods. ( 0,533266724175483 )
Med Decis Making - Standard error of measurement of 5 health utility indexes across the range of health for use in estimating reliability and responsiveness. ( 0,532801359939116 )
Appl Clin Inform - Response to medication dosing alerts for pediatric inpatients using a computerized provider order entry system. ( 0,532669918731244 )
J. Med. Internet Res. - Crowdsourcing black market prices for prescription opioids. ( 0,532570028066624 )
AMIA Annu Symp Proc - Inter-rater agreement among physicians on the clinical significance of drug-drug interactions. ( 0,531096192316979 )
Appl Clin Inform - Impact of clinical reminder redesign on physicians' priority decisions. ( 0,530427384145746 )
J Am Med Inform Assoc - A randomized-controlled trial of computerized alerts to reduce unapproved medication abbreviation use. ( 0,529775321747687 )
BMC Med Inform Decis Mak - Implementation and evaluation of a nurse-centered computerized potassium regulation protocol in the intensive care unit--a before and after analysis. ( 0,528848746735061 )
J Am Med Inform Assoc - Development and use of active clinical decision support for preemptive pharmacogenomics. ( 0,528493346918328 )
J Am Med Inform Assoc - Reduction in medication errors in hospitals due to adoption of computerized provider order entry systems. ( 0,528428984925453 )
Med Biol Eng Comput - Strategy for NSAID administration to aspirin-intolerant asthmatics in combination with PGE2 analogue: a theoretical approach. ( 0,528232908842396 )
Appl Clin Inform - Real-time pharmacy surveillance and clinical decision support to reduce adverse drug events in acute kidney injury: a randomized, controlled trial. ( 0,528001936015791 )
Comput Methods Programs Biomed - Software for symptom association analysis in pediatric gastroesophageal reflux disease. ( 0,527684413169312 )
IEEE Trans Image Process - Statistical modeling of 3-D natural scenes with application to Bayesian stereopsis. ( 0,527526258640072 )
J Am Med Inform Assoc - Paving the COWpath: data-driven design of pediatric order sets. ( 0,527506793550359 )
Methods Inf Med - From adverse drug event detection to prevention. A novel clinical decision support framework for medication safety. ( 0,527069080642076 )
J Am Med Inform Assoc - Factors influencing alert acceptance: a novel approach for predicting the success of clinical decision support. ( 0,526433094209777 )
BMC Med Inform Decis Mak - The predictability of claim-data-based comorbidity-adjusted models could be improved by using medication data. ( 0,52575604502227 )
Comput. Biol. Med. - Approach for streamlining measurement of complex physiological phenotypes of upper airway collapsibility. ( 0,524182093807054 )
J Am Med Inform Assoc - Challenges and remediation for Patient Safety Indicators in the transition to ICD-10-CM. ( 0,522896362199631 )
Int J Med Inform - The effect of using the health smart card vs. CPOE reminder system on the prescribing practices of non-obstetric physicians during outpatient visits for pregnant women in Taiwan. ( 0,522835574099188 )
Comput Math Methods Med - Quantitatively plotting the human face for multivariate data visualisation illustrated by health assessments using laboratory parameters. ( 0,522706924975752 )
Med Decis Making - Overestimation error and unnecessary antibiotic prescriptions for acute cystitis in adult women. ( 0,522470202555189 )
BMC Med Inform Decis Mak - Using a computerized provider order entry system to meet the unique prescribing needs of children: description of an advanced dosing model. ( 0,522324179795554 )
J Am Med Inform Assoc - Overrides of medication-related clinical decision support alerts in outpatients. ( 0,522064976601571 )
J. Med. Internet Res. - Assessment of a new web-based sexual concurrency measurement tool for men who have sex with men. ( 0,521405868985617 )
Med Decis Making - Better medicine by default. ( 0,521142885591616 )
Int J Med Inform - Cost-effectiveness of an electronic medication ordering system (CPOE/CDSS) in hospitalized patients. ( 0,520954519379096 )
Int J Comput Assist Radiol Surg - New method for internal anal sphincter measurements: feasibility study. ( 0,520340735066237 )
J Am Med Inform Assoc - A framework for evaluating the appropriateness of clinical decision support alerts and responses. ( 0,518654338680548 )
J Med Syst - Development of a point-of-care HIV/AIDS medication dosing support system using the Android mobile platform. ( 0,516873833811085 )
Med Biol Eng Comput - Dynamic cerebral autoregulation: different signal processing methods without influence on results and reproducibility. ( 0,516679712019462 )
J Am Med Inform Assoc - Ambulatory prescribing errors among community-based providers in two states. ( 0,516462548534196 )
Med Decis Making - Exploring model uncertainty in economic evaluation of health interventions: the example of rotavirus vaccination in Vietnam. ( 0,515494534621302 )
Int J Med Inform - Prescription order risk factors for pediatric dosing alerts. ( 0,515471460920897 )
Comput Methods Programs Biomed - Physicians' responses to computerized drug-drug interaction alerts for outpatients. ( 0,515357817316024 )
J Am Med Inform Assoc - Understanding and preventing wrong-patient electronic orders: a randomized controlled trial. ( 0,51474154860564 )
AMIA Annu Symp Proc - Unexpected effects of unintended consequences: EMR prescription discrepancies and hemorrhage in patients on warfarin. ( 0,51436853703839 )
AMIA Annu Symp Proc - When you can't tell when it hurts: a preliminary algorithm to assess pain in patients who can't communicate. ( 0,513550783238659 )
J Am Med Inform Assoc - Prevalence of medication administration errors in two medical units with automated prescription and dispensing. ( 0,512407382908258 )
Comput. Biol. Med. - Inter- and intra-observer variability analysis of completely automated cIMT measurement software (AtheroEdge?) and its benchmarking against commercial ultrasound scanner and expert Readers. ( 0,510825798916369 )
J Clin Monit Comput - Non-invasive measurement of cardiac output in obese children and adolescents: comparison of electrical cardiometry and transthoracic Doppler echocardiography. ( 0,509455531412466 )
Int J Med Inform - Comparing the working time between Bar-Code Medication Administration system and traditional medication administration system: an observational study. ( 0,5092309419948 )
J Am Med Inform Assoc - Impact of clinical decision support preventing the use of QT-prolonging medications for patients at risk for torsade de pointes. ( 0,508834867317841 )
J Biomed Inform - Incorporation of expert variability into breast cancer treatment recommendation in designing clinical protocol guided fuzzy rule system models. ( 0,508615376899506 )
J Clin Monit Comput - Validation of continuous and noninvasive hemoglobin monitoring by pulse CO-oximetry in Japanese surgical patients. ( 0,507606524458088 )
Int J Med Inform - Junior doctors' prescribing work after-hours and the impact of computerized decision support. ( 0,50749162574749 )
Int J Med Inform - A trial of indication based prescribing of antihypertensive medications during computerized order entry to improve problem list documentation. ( 0,506464245241002 )
Appl Clin Inform - Matching clinicians to operative cases: a novel application of a patient acuity score. ( 0,50560758544364 )
Comput Math Methods Med - Fully automated detection of corticospinal tract damage in chronic stroke patients. ( 0,505537544993721 )
J Am Med Inform Assoc - Clinical decision support for atypical orders: detection and warning of atypical medication orders submitted to a computerized provider order entry system. ( 0,505120748368729 )
Appl Clin Inform - Drug interaction alert override rates in the Meaningful Use era: no evidence of progress. ( 0,505044539413124 )
AMIA Annu Symp Proc - Evaluating the effectiveness of clinical alerts: a signal detection approach. ( 0,50438178961567 )
J Am Med Inform Assoc - Optimization of drug-drug interaction alert rules in a pediatric hospital's electronic health record system using a visual analytics dashboard. ( 0,503859863358894 )
J Am Med Inform Assoc - Immediate financial impact of computerized clinical decision support for long-term care residents with renal insufficiency: a case study. ( 0,502765576340467 )
AMIA Annu Symp Proc - Identifying Deviations from Usual Medical Care using a Statistical Approach. ( 0,502656172404617 )
J Clin Monit Comput - The effect of desflurane versus propofol on regional cerebral oxygenation in the sitting position for shoulder arthroscopy. ( 0,502572729317729 )
J Am Med Inform Assoc - Failure to utilize functions of an electronic prescribing system and the subsequent generation of 'technically preventable' computerized alerts. ( 0,502189233432027 )
Perspect Health Inf Manag - Projected impact of the ICD-10-CM/PCS conversion on longitudinal data and the Joint Commission Core Measures. ( 0,501748235967433 )
J Am Med Inform Assoc - Sensitivity and specificity of dosing alerts for dosing errors among hospitalized pediatric patients. ( 0,501372452768708 )