Comput Methods Programs Biomed - Mechanical ventilation and thoracic artificial lung assistance during mechanical circulatory support with PUCA pump: in silico study.

Tópicos

{ blood(1257) pressur(1144) flow(957) }
{ activ(1452) weight(1219) physic(1104) }
{ model(2220) cell(1177) simul(1124) }
{ monitor(1329) mobil(1314) devic(1160) }
{ featur(3375) classif(2383) classifi(1994) }
{ system(1050) medic(1026) inform(1018) }
{ chang(1828) time(1643) increas(1301) }
{ design(1359) user(1324) use(1319) }
{ model(2656) set(1616) predict(1553) }
{ activ(1138) subject(705) human(624) }
{ algorithm(1844) comput(1787) effici(935) }
{ research(1085) discuss(1038) issu(1018) }
{ visual(1396) interact(850) tool(830) }
{ age(1611) year(1155) adult(843) }
{ bind(1733) structur(1185) ligand(1036) }
{ model(3480) simul(1196) paramet(876) }
{ group(2977) signific(1463) compar(1072) }
{ use(1733) differ(960) four(931) }
{ method(2212) result(1239) propos(1039) }
{ patient(2315) diseas(1263) diabet(1191) }
{ assess(1506) score(1403) qualiti(1306) }
{ surgeri(1148) surgic(1085) robot(1054) }
{ framework(1458) process(801) describ(734) }
{ method(1557) propos(1049) approach(1037) }
{ care(1570) inform(1187) nurs(1089) }
{ state(1844) use(1261) util(961) }
{ data(3008) multipl(1320) sourc(1022) }
{ structur(1116) can(940) graph(676) }
{ high(1669) rate(1365) level(1280) }
{ use(976) code(926) identifi(902) }
{ model(3404) distribut(989) bayesian(671) }
{ can(774) often(719) complex(702) }
{ imag(1947) propos(1133) code(1026) }
{ data(1737) use(1416) pattern(1282) }
{ inform(2794) health(2639) internet(1427) }
{ system(1976) rule(880) can(841) }
{ measur(2081) correl(1212) valu(896) }
{ imag(1057) registr(996) error(939) }
{ sequenc(1873) structur(1644) protein(1328) }
{ method(1219) similar(1157) match(930) }
{ imag(2830) propos(1344) filter(1198) }
{ network(2748) neural(1063) input(814) }
{ imag(2675) segment(2577) method(1081) }
{ take(945) account(800) differ(722) }
{ studi(2440) review(1878) systemat(933) }
{ motion(1329) object(1292) video(1091) }
{ treatment(1704) effect(941) patient(846) }
{ problem(2511) optim(1539) algorithm(950) }
{ error(1145) method(1030) estim(1020) }
{ learn(2355) train(1041) set(1003) }
{ concept(1167) ontolog(924) domain(897) }
{ clinic(1479) use(1117) guidelin(835) }
{ extract(1171) text(1153) clinic(932) }
{ data(1714) softwar(1251) tool(1186) }
{ control(1307) perform(991) simul(935) }
{ general(901) number(790) one(736) }
{ method(984) reconstruct(947) comput(926) }
{ search(2224) databas(1162) retriev(909) }
{ featur(1941) imag(1645) propos(1176) }
{ case(1353) use(1143) diagnosi(1136) }
{ howev(809) still(633) remain(590) }
{ data(3963) clinic(1234) research(1004) }
{ studi(1410) differ(1259) use(1210) }
{ risk(3053) factor(974) diseas(938) }
{ perform(999) metric(946) measur(919) }
{ import(1318) role(1303) understand(862) }
{ model(2341) predict(2261) use(1141) }
{ compound(1573) activ(1297) structur(1058) }
{ perform(1367) use(1326) method(1137) }
{ studi(1119) effect(1106) posit(819) }
{ spatial(1525) area(1432) region(1030) }
{ record(1888) medic(1808) patient(1693) }
{ health(3367) inform(1360) care(1135) }
{ ehr(2073) health(1662) electron(1139) }
{ research(1218) medic(880) student(794) }
{ patient(2837) hospit(1953) medic(668) }
{ data(2317) use(1299) case(1017) }
{ medic(1828) order(1363) alert(1069) }
{ signal(2180) analysi(812) frequenc(800) }
{ cost(1906) reduc(1198) effect(832) }
{ sampl(1606) size(1419) use(1276) }
{ gene(2352) biolog(1181) express(1162) }
{ first(2504) two(1366) second(1323) }
{ intervent(3218) particip(2042) group(1664) }
{ time(1939) patient(1703) rate(768) }
{ patient(1821) servic(1111) care(1106) }
{ use(2086) technolog(871) perceiv(783) }
{ can(981) present(881) function(850) }
{ analysi(2126) use(1163) compon(1037) }
{ health(1844) social(1437) communiti(874) }
{ cancer(2502) breast(956) screen(824) }
{ drug(1928) target(777) effect(648) }
{ result(1111) use(1088) new(759) }
{ implement(1333) system(1263) develop(1122) }
{ survey(1388) particip(1329) question(1065) }
{ estim(2440) model(1874) function(577) }
{ decis(3086) make(1611) patient(1517) }
{ process(1125) use(805) approach(778) }
{ method(1969) cluster(1462) data(1082) }
{ detect(2391) sensit(1101) algorithm(908) }

Resumo

Patients assisted with left ventricular assist device (LVAD) may require prolonged mechanical ventilatory assistance secondary to postoperative respiratory failure. The goal of this work is the study of the interdependent effects LVAD like pulsatile catheter (PUCA) pump and mechanical ventilatory support or thoracic artificial lung (TAL), by the hemodynamic point of view, using a numerical simulator of the human cardiovascular system. In the simulator, different circulatory sections are described using lumped parameter models. Lumped parameter models have been designed to describe the hydrodynamic behavior of both PUCA pump and thoracic artificial lung. Ventricular behavior atrial and septum functions were reproduced using variable elastance model. Starting from simulated pathological conditions we studied the effects produced on some hemodynamic variables by simultaneous PUCA pump, thoracic artificial lung or mechanical ventilation assistance. Thoracic artificial lung was applied in parallel or in hybrid mode. The effects of mechanical ventilation have been simulated by changing mean intrathoracic pressure value from -4 mmHg to +5 mmHg. The hemodynamic variables observed during the simulations, in different assisted conditions, were: left and right ventricular end systolic (diastolic) volume, systolic/diastolic aortic pressure, mean pulmonary arterial pressure, left and right mean atrial pressure, mean systemic venous pressure and the total blood flow. Results show that the application of PUCA (without mechanical ventilatory assistance) increases the total blood flow, reduces the left ventricular end systolic volume and increases the diastolic aortic pressure. Parallel TAL assistance increases the right ventricular end diastolic (systolic) volume reduction both when PUCA is switched "ON" and both when PUCA is switched "OFF". By switching "OFF" the PUCA pump, it seems that parallel thoracic artificial lung assistance produces a greater cardiac output (respect to hybrid TAL assistance). Results concerning PUCA and TAL interaction produced by simulations cannot be compared with "in vivo" results since they are not presented in literature. But results concerning the effects produced by LVAD and mechanical ventilation have a trend consistent with those presented in literature.

Resumo Limpo

patient assist left ventricular assist devic lvad may requir prolong mechan ventilatori assist secondari postop respiratori failur goal work studi interdepend effect lvad like pulsatil cathet puca pump mechan ventilatori support thorac artifici lung tal hemodynam point view use numer simul human cardiovascular system simul differ circulatori section describ use lump paramet model lump paramet model design describ hydrodynam behavior puca pump thorac artifici lung ventricular behavior atrial septum function reproduc use variabl elast model start simul patholog condit studi effect produc hemodynam variabl simultan puca pump thorac artifici lung mechan ventil assist thorac artifici lung appli parallel hybrid mode effect mechan ventil simul chang mean intrathorac pressur valu mmhg mmhg hemodynam variabl observ simul differ assist condit left right ventricular end systol diastol volum systolicdiastol aortic pressur mean pulmonari arteri pressur left right mean atrial pressur mean system venous pressur total blood flow result show applic puca without mechan ventilatori assist increas total blood flow reduc left ventricular end systol volum increas diastol aortic pressur parallel tal assist increas right ventricular end diastol systol volum reduct puca switch puca switch switch puca pump seem parallel thorac artifici lung assist produc greater cardiac output respect hybrid tal assist result concern puca tal interact produc simul compar vivo result sinc present literatur result concern effect produc lvad mechan ventil trend consist present literatur

Resumos Similares

Comput Math Methods Med - Numerical study for blood flow in pulmonary arteries after repair of tetralogy of Fallot. ( 0,874499903757946 )
J Clin Monit Comput - Pulmonary artery pulsatility is the main cause of cardiogenic oscillations. ( 0,855854772851495 )
Comput. Biol. Med. - The hemodynamic alterations induced by the vascular angular deformation in stent-assisted coiling of bifurcation aneurysms. ( 0,854923724401904 )
J Clin Monit Comput - Noninvasive continuous hemodynamic monitoring. ( 0,851013997033088 )
J Clin Monit Comput - Heart sounds analysis via esophageal stethoscope system in beagles. ( 0,845096030210744 )
J Clin Monit Comput - Capability of a new paediatric oesophageal Doppler monitor to detect changes in cardiac output during testing of external pacemakers after cardiac surgery. ( 0,845083174371874 )
J Clin Monit Comput - Assessment of the effect of rapid crystalloid infusion on stroke volume variation and pleth variability index after a preoperative fast. ( 0,84361675421267 )
J Clin Monit Comput - Hemodynamic volumetry using transpulmonary ultrasound dilution (TPUD) technology in a neonatal animal model. ( 0,841380887176593 )
J Clin Monit Comput - Continuous minimally invasive peri-operative monitoring of cardiac output by pulmonary capnotracking: comparison with thermodilution and transesophageal echocardiography. ( 0,840411687089374 )
Comput Math Methods Med - Mathematical analysis of non-Newtonian blood flow in stenosis narrow arteries. ( 0,839355576903557 )
J Clin Monit Comput - Transesophageal echocardiography and intraoperative phlebotomy during surgical repair of coarctation of aorta in a patient with atrial septal defect, moderately severe mitral regurgitation and severe pulmonary hypertension. ( 0,837840825921203 )
Comput. Biol. Med. - Biomechanical behaviors of curved artery with flexible wall: a numerical study using fluid-structure interaction method. ( 0,834871914815902 )
Comput Math Methods Med - Plasma volume expansion resulting from intravenous glucose tolerance test. ( 0,833088393396146 )
Comput. Biol. Med. - Simulation of a pulsatile non-Newtonian flow past a stenosed 2D artery with atherosclerosis. ( 0,832573165517586 )
J Clin Monit Comput - In-line pressure within a HOTLINE? Fluid Warmer, under various flow conditions. ( 0,832344752968106 )
Med Biol Eng Comput - Mechanical behaviour and rupture of normal and pathological human ascending aortic wall. ( 0,832082436316932 )
Comput Methods Programs Biomed - In silico study of the haemodynamic effects induced by mechanical ventilation and biventricular pacemaker. ( 0,832038201113087 )
J Clin Monit Comput - Impact of central hypovolemia on photoplethysmographic waveform parameters in healthy volunteers. Part 1: time domain analysis. ( 0,828708063538748 )
Med Biol Eng Comput - Assessment of dynamic cerebral autoregulation and cerebral carbon dioxide reactivity during normothermic cardiopulmonary bypass. ( 0,824030214995168 )
J Clin Monit Comput - Decrease in pulmonary artery pressure after administration of thoracic epidural anesthesia in a patient with Marfan syndrome awaiting aortic valve replacement procedure. ( 0,821837960622621 )
Med Biol Eng Comput - Model-based correction of the influence of body position on continuous segmental and hand-to-foot bioimpedance measurements. ( 0,820543203400673 )
Comput Methods Programs Biomed - A model of perfusion of the healthy human lung. ( 0,820004752884661 )
Comput Math Methods Med - Simulation of the Frank-Starling Law of the Heart. ( 0,81898867485352 )
Comput Math Methods Med - Mathematical modeling of radiofrequency ablation for varicose veins. ( 0,816239398082163 )
Med Biol Eng Comput - Coronary-aortic interaction during ventricular isovolumic contraction. ( 0,814604867999999 )
Med Biol Eng Comput - Arterial reservoir-excess pressure and ventricular work. ( 0,813863406788847 )
J Clin Monit Comput - Assessment of cerebral oxygenation using near infrared spectroscopy during isovolemic hemodilution in pediatric patients. ( 0,811573744508901 )
J Clin Monit Comput - Changes in R-Wave amplitude in DII lead is less sensitive than pulse pressure variation to detect changes in stroke volume after fluid challenge in ICU patients postoperatively to cardiac surgery. ( 0,810923567535514 )
J Clin Monit Comput - Variations in the pre-ejection period induced by deep breathing do not predict the hemodynamic response to early haemorrhage in healthy volunteers. ( 0,80933140216431 )
Med Biol Eng Comput - The effect of aortic wall and aortic leaflet stiffening on coronary hemodynamic: a fluid-structure interaction study. ( 0,806616415584304 )
J Clin Monit Comput - The changes of pulmonary blood flow in non-ventilated lung during one lung ventilation. ( 0,806481640637731 )
J Clin Monit Comput - Cardiopulmonary interactions and volume status assessment. ( 0,806122740969908 )
J Clin Monit Comput - Detection of changes in muscle oxygen saturation in the human leg: a comparison of two near-infrared spectroscopy devices. ( 0,804648234970604 )
J Clin Monit Comput - Comparison of cardiac output determined by bioimpedance and bioreactance methods at rest and during exercise. ( 0,801543973618094 )
Comput. Biol. Med. - Blood glucose level reconstruction as a function of transcapillary glucose transport. ( 0,800331946138918 )
Med Biol Eng Comput - Modeling hemodynamics in an unoccluded and partially occluded inferior vena cava under rest and exercise conditions. ( 0,798947577711636 )
J Clin Monit Comput - Fluid responsiveness is about stroke volume, and not pulse pressure Yogi: the power of Doppler fluid management and cardiovascular monitoring. ( 0,798921778654093 )
Med Biol Eng Comput - Cardiac oxygen supply is compromised during the night in hypertensive patients. ( 0,797576358087721 )
Comput. Biol. Med. - Effect of CPAP therapy on daytime cardiovascular regulations in patients with obstructive sleep apnea. ( 0,79689593796052 )
Med Biol Eng Comput - A coupled flow-acoustic computational study of bruits from a modeled stenosed artery. ( 0,794274871009894 )
Comput. Biol. Med. - Modeling of heart sound morphology and analysis of the morphological variations induced by respiration. ( 0,793517536751012 )
Comput Math Methods Med - Simulation of exercise-induced syncope in a heart model with severe aortic valve stenosis. ( 0,793224349182546 )
Comput Math Methods Med - Evaluation of a model-based hemodynamic monitoring method in a porcine study of septic shock. ( 0,792720545813404 )
Med Biol Eng Comput - Characterization of skin dermis microcirculation in flow-mediated dilation using optical sensor with pressurization mechanism. ( 0,792699657710791 )
Comput. Biol. Med. - A semi-automated computer tool for the analysis of retinal vessel diameter dynamics. ( 0,791946399029612 )
Comput Math Methods Med - Computational fluid dynamics simulations of contrast agent bolus dispersion in a coronary bifurcation: impact on MRI-based quantification of myocardial perfusion. ( 0,790932300575383 )
J Clin Monit Comput - The relationship between the area of peripherally-derived pressure volume loops and systemic vascular resistance. ( 0,790182732962069 )
Med Biol Eng Comput - Electropermeabilization of endocytotic vesicles in B16 F1 mouse melanoma cells. ( 0,788965874836271 )
J Clin Monit Comput - Arterial pressure waveform derived cardiac output FloTrac/Vigileo system (third generation software): comparison of two monitoring sites with the thermodilution cardiac output. ( 0,788435890665551 )
Comput Math Methods Med - Computational fluid dynamics analysis of the effect of plaques in the left coronary artery. ( 0,78785322085687 )
IEEE J Biomed Health Inform - Experimental investigation of the influence of the aortic stiffness on hemodynamics in the ascending aorta. ( 0,78781963066877 )
J Clin Monit Comput - Combination of continuous pulse pressure variation monitoring and cardiac filling pressure to predict fluid responsiveness. ( 0,787740809221152 )
Comput Math Methods Med - Evaluating the hemodynamical response of a cardiovascular system under support of a continuous flow left ventricular assist device via numerical modeling and simulations. ( 0,787039135959888 )
Comput Math Methods Med - Impact of competitive flow on hemodynamics in coronary surgery: numerical study of ITA-LAD model. ( 0,786637374533283 )
Comput Methods Programs Biomed - Measurements of the left atrium and pulmonary veins for analysis of reverse structural remodeling following cardiac ablation therapy. ( 0,786458395566801 )
Med Biol Eng Comput - Determinants of vascular and cardiac baroreflex sensitivity values in a random population sample. ( 0,784857645551841 )
J Clin Monit Comput - Pleth variability index-directed fluid management in abdominal surgery under combined general and epidural anesthesia. ( 0,784393385841538 )
Comput. Biol. Med. - Numerical investigation of blood flow in three-dimensional porcine left anterior descending artery with various stenoses. ( 0,782870762542164 )
Comput Methods Programs Biomed - A model of ventilation of the healthy human lung. ( 0,776468050219312 )
J Clin Monit Comput - Impact of skin incision on the pleth variability index. ( 0,776331177384235 )
J Clin Monit Comput - Radial artery cannulation decreases the distal arterial blood flow measured by power Doppler ultrasound. ( 0,77579874466663 )
J Clin Monit Comput - Transthoracic electrical bioimpedence cardiac output: comparison with multigated equillibrium radionuclide cardiography. ( 0,774936739057508 )
J Clin Monit Comput - The use of a noninvasive hemoglobin monitor for determining fluid distribution and elimination in pediatric patients undergoing minor surgery. ( 0,774644212994881 )
Wiley Interdiscip Rev Syst Biol Med - Integration of cardiovascular regulation by the blood/endothelium cell-free layer. ( 0,771363504020386 )
Med Biol Eng Comput - The consequences of the mechanical environment of peripheral arteries for nitinol stenting. ( 0,771088378152717 )
J Clin Monit Comput - Arterial line for monitoring SpO2 in patients with ischemic peripheries. ( 0,770827890952723 )
Comput. Biol. Med. - A general model for continuous noninvasive pulmonary artery pressure estimation. ( 0,769749147251294 )
Med Biol Eng Comput - Computational model for estimating the short- and long-term cardiac response to arteriovenous fistula creation for hemodialysis. ( 0,767431211796731 )
Med Biol Eng Comput - Aortic pressure wave reconstruction during exercise is improved by adaptive filtering: a pilot study. ( 0,765423116786658 )
J Clin Monit Comput - The effect of endotracheal tube cuff pressure change during gynecological laparoscopic surgery on postoperative sore throat: a control study. ( 0,764599394968866 )
J Clin Monit Comput - Impact of central hypovolemia on photoplethysmographic waveform parameters in healthy volunteers part 2: frequency domain analysis. ( 0,764191371514607 )
Med Biol Eng Comput - Timing and size of flow impingement in a giant intracranial aneurysm at the internal carotid artery. ( 0,763192842325583 )
Telemed J E Health - The informative contribution of the virtual medical visit in a new heart failure telemedicine integrated system. ( 0,762581134899464 )
Comput Methods Programs Biomed - Computer simulation of MHD blood conveying gold nanoparticles as a third grade non-Newtonian nanofluid in a hollow porous vessel. ( 0,760776237219448 )
J Clin Monit Comput - Bedside assessment of passive leg raising effects on venous return. ( 0,760359694871419 )
J Clin Monit Comput - Continuous measurement of cardiac output with the electrical velocimetry method in patients under spinal anesthesia for cesarean delivery. ( 0,756969445170491 )
J Clin Monit Comput - Thoracic impedance measures tissue characteristics in the vicinity of the electrodes, not intervening lung water: implications for heart failure monitoring. ( 0,756558547143995 )
J Clin Monit Comput - Continuous real time endotracheal tube cuff pressure waveform. ( 0,755997805305956 )
J Clin Monit Comput - Reference values for volumetric capnography-derived non-invasive parameters in healthy individuals. ( 0,755853055026418 )
J Clin Monit Comput - Non-invasive cardiac output and oxygen delivery measurement in an infant with critical anemia. ( 0,755823410522264 )
J Clin Monit Comput - The effects of cardiac output and pulmonary arterial hypertension on volumetric capnography derived-variables during normoxia and hypoxia. ( 0,755025524552578 )
J Clin Monit Comput - Evaluation of mean systemic filling pressure from pulse contour cardiac output and central venous pressure. ( 0,754306817633535 )
Comput. Biol. Med. - Computational analysis of the importance of flow synchrony for cardiac ventricular assist devices. ( 0,753734795125269 )
J Clin Monit Comput - A model-based decision support system for critiquing mechanical ventilation treatments. ( 0,75163727988752 )
J Clin Monit Comput - Tako-tsubo cardiomyopathy and microcirculation. ( 0,751349517513714 )
Med Biol Eng Comput - Monitoring intracellular, interstitial, and intravascular volume changes during fluid management procedures. ( 0,750824621986058 )
Comput Math Methods Med - Influence of distal resistance and proximal stiffness on hemodynamics and RV afterload in progression and treatments of pulmonary hypertension: a computational study with validation using animal models. ( 0,749046060027881 )
J Clin Monit Comput - Additional hemodynamic measurements with an esophageal Doppler monitor: a preliminary report of compliance, force, kinetic energy, and afterload in the clinical setting. ( 0,747696014623738 )
Med Biol Eng Comput - Non-invasive monitoring of central blood pressure by electrical impedance tomography: first experimental evidence. ( 0,747116719931195 )
J Med Syst - Mathematical models of real geometrical factors in restricted blood vessels for the analysis of CAD (coronary artery diseases) using Legendre, Boubaker and Bessel polynomials. ( 0,745428177299021 )
J Clin Monit Comput - Analysis of plethysmographic waveform changes induced by beach chair positioning under general anesthesia. ( 0,741680234785234 )
Med Biol Eng Comput - Transesophageal left ventricular electrogram-recording and temporary pacing to improve patient selection for cardiac resynchronization. ( 0,739960586859338 )
Med Biol Eng Comput - Effect of respiration on Korotkoff sounds and oscillometric cuff pressure pulses during blood pressure measurement. ( 0,738876709995384 )
J Clin Monit Comput - Continuous non-invasive monitoring improves blood pressure stability in upright position: randomized controlled trial. ( 0,738402685655057 )
J Clin Monit Comput - Radial-femoral concordance in time and frequency domain-based estimates of systemic arterial respiratory variation. ( 0,737280814892288 )
Comput Methods Programs Biomed - Quantitative analysis of digital subtraction angiography using optical flow method on occlusive cerebrovascular disease. ( 0,734224764212092 )
J Clin Monit Comput - Monitoring oxygenation. ( 0,733762913643123 )
Med Biol Eng Comput - Investigation of photoplethysmographic signals and blood oxygen saturation values on healthy volunteers during cuff-induced hypoperfusion using a multimode PPG/SpO2 sensor. ( 0,732695259507388 )
J Clin Monit Comput - Elucidating the fuzziness in physician decision making in ARDS. ( 0,730030467895246 )
Med Biol Eng Comput - Haemodynamic forces on in vitro thrombi: a numerical analysis. ( 0,72852329337697 )