Comput Methods Programs Biomed - Subject-specific finite element simulation of the human femur considering inhomogeneous material properties: a straightforward method and convergence study.

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Resumo

In numerical finite element (FE) simulations of human bones subject-specific models are necessary to reproduce the physiological conditions, which include the determination of inhomogeneous material properties from computed tomography (CT) scans and their implementation in the numerical model. In the present approach common software packages are directly used for the entire simulation process from segmentation of CT scans, surface reconstruction, mesh generation, calculation of mean element densities to FE simulation. The influence of the mesh discretisation level on the maximum displacement, the total system energy and the principal surface stress distribution of eight human femurs was analysed. Both the maximum displacement and the total system energy showed typical convergence behaviour towards an asymptotic value with decreasing element size. The principal surface stress distribution followed similar qualitative trends at all mesh discretisation levels studied for the same femur. However, the stress distributions did not converge with decreasing element size and still differed significantly between the two smallest element sizes studied of approximately 2mm and 1mm. The magnitude of convergence differed among the individual femurs. Thus, individual convergence studies in terms of local stress or strain distributions are necessary for accurately predicting local stress and strain values in subject-specific FE bone models.

Resumo Limpo

numer finit element fe simul human bone subjectspecif model necessari reproduc physiolog condit includ determin inhomogen materi properti comput tomographi ct scan implement numer model present approach common softwar packag direct use entir simul process segment ct scan surfac reconstruct mesh generat calcul mean element densiti fe simul influenc mesh discretis level maximum displac total system energi princip surfac stress distribut eight human femur analys maximum displac total system energi show typic converg behaviour toward asymptot valu decreas element size princip surfac stress distribut follow similar qualit trend mesh discretis level studi femur howev stress distribut converg decreas element size still differ signific two smallest element size studi approxim mm mm magnitud converg differ among individu femur thus individu converg studi term local stress strain distribut necessari accur predict local stress strain valu subjectspecif fe bone model

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