Comput Methods Programs Biomed - Elastic image registration for guiding focal laser ablation of prostate cancer: preliminary results.

Tópicos

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Resumo

RPOSE: To guide ultrasound-driven prostate photodynamic therapy using information from MRI-based treatment planning.METHODS: Robust points matching (RPM) and thin plate splines (TPS) are used to solve correspondences and to map optimally positioned landmarks from MR images to transrectal ultrasound (TRUS) images. The algorithm uses a reduced number of anatomical markers that are initialized on the images.RESULTS: Both phantom and patient data were used to evaluate precision and robustness of the method. Mean registration error (?standard deviation) was of 2.18?0.25 mm and 1.55?0.31 mm for patient prostate and urethra, respectively. Repeated tests with different markers initialization conditions showed that the quality of registration was neither influenced by the number of markers nor to the human observer.CONCLUSION: This method allows for satisfyingly accurate and robust non rigid registration of MRI and TRUS and provides practitioners with substantial help in mapping treatment planning from pre-operative MRI to interventional TRUS.

Resumo Limpo

rpose guid ultrasounddriven prostat photodynam therapi use inform mribas treatment planningmethod robust point match rpm thin plate spline tps use solv correspond map optim posit landmark mr imag transrect ultrasound trus imag algorithm use reduc number anatom marker initi imagesresult phantom patient data use evalu precis robust method mean registr error standard deviat mm mm patient prostat urethra respect repeat test differ marker initi condit show qualiti registr neither influenc number marker human observerconclus method allow satisfi accur robust non rigid registr mri trus provid practition substanti help map treatment plan preoper mri intervent trus

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