Comput Methods Programs Biomed - A SAS macro for target dose estimation by reinforced urn processes in phase I clinical trials.

Tópicos

{ result(1111) use(1088) new(759) }
{ system(1976) rule(880) can(841) }
{ framework(1458) process(801) describ(734) }
{ design(1359) user(1324) use(1319) }
{ model(3404) distribut(989) bayesian(671) }
{ method(1557) propos(1049) approach(1037) }
{ data(1714) softwar(1251) tool(1186) }
{ case(1353) use(1143) diagnosi(1136) }
{ first(2504) two(1366) second(1323) }
{ process(1125) use(805) approach(778) }
{ can(774) often(719) complex(702) }
{ take(945) account(800) differ(722) }
{ algorithm(1844) comput(1787) effici(935) }
{ estim(2440) model(1874) function(577) }
{ decis(3086) make(1611) patient(1517) }
{ data(1737) use(1416) pattern(1282) }
{ imag(2830) propos(1344) filter(1198) }
{ motion(1329) object(1292) video(1091) }
{ treatment(1704) effect(941) patient(846) }
{ surgeri(1148) surgic(1085) robot(1054) }
{ problem(2511) optim(1539) algorithm(950) }
{ error(1145) method(1030) estim(1020) }
{ chang(1828) time(1643) increas(1301) }
{ control(1307) perform(991) simul(935) }
{ care(1570) inform(1187) nurs(1089) }
{ studi(1410) differ(1259) use(1210) }
{ perform(999) metric(946) measur(919) }
{ research(1085) discuss(1038) issu(1018) }
{ model(2341) predict(2261) use(1141) }
{ state(1844) use(1261) util(961) }
{ patient(2837) hospit(1953) medic(668) }
{ medic(1828) order(1363) alert(1069) }
{ cost(1906) reduc(1198) effect(832) }
{ group(2977) signific(1463) compar(1072) }
{ use(2086) technolog(871) perceiv(783) }
{ drug(1928) target(777) effect(648) }
{ activ(1452) weight(1219) physic(1104) }
{ imag(1947) propos(1133) code(1026) }
{ inform(2794) health(2639) internet(1427) }
{ measur(2081) correl(1212) valu(896) }
{ imag(1057) registr(996) error(939) }
{ bind(1733) structur(1185) ligand(1036) }
{ sequenc(1873) structur(1644) protein(1328) }
{ method(1219) similar(1157) match(930) }
{ featur(3375) classif(2383) classifi(1994) }
{ network(2748) neural(1063) input(814) }
{ imag(2675) segment(2577) method(1081) }
{ patient(2315) diseas(1263) diabet(1191) }
{ studi(2440) review(1878) systemat(933) }
{ assess(1506) score(1403) qualiti(1306) }
{ learn(2355) train(1041) set(1003) }
{ concept(1167) ontolog(924) domain(897) }
{ clinic(1479) use(1117) guidelin(835) }
{ extract(1171) text(1153) clinic(932) }
{ model(2220) cell(1177) simul(1124) }
{ general(901) number(790) one(736) }
{ method(984) reconstruct(947) comput(926) }
{ search(2224) databas(1162) retriev(909) }
{ featur(1941) imag(1645) propos(1176) }
{ howev(809) still(633) remain(590) }
{ data(3963) clinic(1234) research(1004) }
{ risk(3053) factor(974) diseas(938) }
{ system(1050) medic(1026) inform(1018) }
{ import(1318) role(1303) understand(862) }
{ visual(1396) interact(850) tool(830) }
{ compound(1573) activ(1297) structur(1058) }
{ perform(1367) use(1326) method(1137) }
{ studi(1119) effect(1106) posit(819) }
{ blood(1257) pressur(1144) flow(957) }
{ spatial(1525) area(1432) region(1030) }
{ record(1888) medic(1808) patient(1693) }
{ health(3367) inform(1360) care(1135) }
{ model(3480) simul(1196) paramet(876) }
{ monitor(1329) mobil(1314) devic(1160) }
{ ehr(2073) health(1662) electron(1139) }
{ research(1218) medic(880) student(794) }
{ model(2656) set(1616) predict(1553) }
{ data(2317) use(1299) case(1017) }
{ age(1611) year(1155) adult(843) }
{ signal(2180) analysi(812) frequenc(800) }
{ sampl(1606) size(1419) use(1276) }
{ gene(2352) biolog(1181) express(1162) }
{ data(3008) multipl(1320) sourc(1022) }
{ intervent(3218) particip(2042) group(1664) }
{ activ(1138) subject(705) human(624) }
{ time(1939) patient(1703) rate(768) }
{ patient(1821) servic(1111) care(1106) }
{ can(981) present(881) function(850) }
{ analysi(2126) use(1163) compon(1037) }
{ health(1844) social(1437) communiti(874) }
{ structur(1116) can(940) graph(676) }
{ high(1669) rate(1365) level(1280) }
{ cancer(2502) breast(956) screen(824) }
{ use(976) code(926) identifi(902) }
{ use(1733) differ(960) four(931) }
{ implement(1333) system(1263) develop(1122) }
{ survey(1388) particip(1329) question(1065) }
{ method(1969) cluster(1462) data(1082) }
{ method(2212) result(1239) propos(1039) }
{ detect(2391) sensit(1101) algorithm(908) }

Resumo

The reinforced urn processes (RUPs) approach can estimate the target dose on the basis of the prior distribution function precisely and conveniently without the requirements about the explicit-estimated dose-response curve and the posterior complicated inference. The application of the RUPs approach was not discussed from the perspective of phase I clinical trial in the previous studies which just focused on the theory and methodology. And the modification of the traditional RUPs design should be considered for the purposes of ethnics and efficiency. A SAS macro was designed to explore the appropriate parameter settings according to the simulation outcomes in different situations and apply the RUPs approach for two state processes in phase I clinical trail with the modified RUPs design. The posterior estimation can be obtained precisely and efficiently with application of SAS program following the appropriate workflow and determination rule which were described in the example.

Resumo Limpo

reinforc urn process rup approach can estim target dose basi prior distribut function precis conveni without requir explicitestim doserespons curv posterior complic infer applic rup approach discuss perspect phase clinic trial previous studi just focus theori methodolog modif tradit rup design consid purpos ethnic effici sas macro design explor appropri paramet set accord simul outcom differ situat appli rup approach two state process phase clinic trail modifi rup design posterior estim can obtain precis effici applic sas program follow appropri workflow determin rule describ exampl

Resumos Similares

BMC Med Inform Decis Mak - Intelligent Therapy Assistant (ITA) for cognitive rehabilitation in patients with acquired brain injury. ( 0,591352946707043 )
J Med Syst - Prediction of low back pain with two expert systems. ( 0,557282137055989 )
J Med Syst - A collaboration tool based on SNOCAP-HET. ( 0,554286967691999 )
Neural Comput - Risk-sensitive reinforcement learning. ( 0,548021599499529 )
J Chem Inf Model - APL@Voro: a Voronoi-based membrane analysis tool for GROMACS trajectories. ( 0,533703967261283 )
Med Decis Making - Bivariate random-effects meta-analysis of sensitivity and specificity with the Bayesian SAS PROC MCMC: methodology and empirical evaluation in 50 meta-analyses. ( 0,526152080439178 )
Int J Med Inform - Sirius: a web-based system for retinal image analysis. ( 0,522283193257558 )
Comput. Biol. Med. - Using experts feedback in clinical case resolution and arbitration as accuracy diagnosis methodology. ( 0,517683056457438 )
AMIA Annu Symp Proc - An Empirical Validation of Recursive Noisy OR (RNOR) Rule for Asthma Prediction. ( 0,515635568334232 )
J. Med. Internet Res. - Movement-based interaction applied to physical rehabilitation therapies. ( 0,514543079442122 )
Neural Comput - A common network architecture efficiently implements a variety of sparsity-based inference problems. ( 0,514120986101049 )
Comput Methods Programs Biomed - Design of an efficient framework for fast prototyping of customized human-computer interfaces and virtual environments for rehabilitation. ( 0,513406248274162 )
BMC Med Inform Decis Mak - The cloud paradigm applied to e-Health. ( 0,511666070813456 )
AMIA Annu Symp Proc - Medication Reconciliation: Work Domain Ontology, prototype development, and a predictive model. ( 0,507468037933237 )
Neural Comput - Conditional association. ( 0,506878363787285 )
Comput Math Methods Med - Implementation of a low-cost mobile devices to support medical diagnosis. ( 0,506784920325267 )
Artif Intell Med - NICeSim: an open-source simulator based on machine learning techniques to support medical research on prenatal and perinatal care decision making. ( 0,506453401767344 )
Comput Methods Programs Biomed - A Kinect-based system for cognitive rehabilitation exercises monitoring. ( 0,50395263067897 )
Methods Inf Med - A business rules design framework for a pharmaceutical validation and alert system. ( 0,502258440272113 )
Comput Methods Programs Biomed - Consultation system for determining the patients' readiness for weaning from long-term mechanical ventilation. ( 0,49806492501269 )
IEEE J Biomed Health Inform - A statistical characterization of the finger tapping test: modeling, estimation, and applications. ( 0,496403447059506 )
J. Comput. Biol. - On the inference of dirichlet mixture priors for protein sequence comparison. ( 0,495781046683224 )
Comput Methods Programs Biomed - An experimental comparison of fuzzy logic and analytic hierarchy process for medical decision support systems. ( 0,495368370604851 )
Comput. Aided Surg. - Surgical workflow analysis with Gaussian mixture multivariate autoregressive (GMMAR) models: a simulation study. ( 0,494166211107401 )
J Med Syst - A meta-composite software development approach for translational research. ( 0,489269660785357 )
Comput Methods Programs Biomed - GelClust: a software tool for gel electrophoresis images analysis and dendrogram generation. ( 0,48814781397471 )
Med Decis Making - Quantitative benefit-risk assessment using only qualitative information on utilities. ( 0,487476081423143 )
Res Synth Methods - Bayesian meta-analysis of coefficient alpha. ( 0,485945510928247 )
J Med Syst - Comparing four softwares based on ISO 9241 part 10. ( 0,485907498472498 )
Comput Methods Programs Biomed - The methodology of Dynamic Uncertain Causality Graph for intelligent diagnosis of vertigo. ( 0,48320072883296 )
Int J Comput Assist Radiol Surg - MITK-ToF--range data within MITK. ( 0,478945302221502 )
Spat Spatiotemporal Epidemiol - Supervised learning and prediction of spatial epidemics. ( 0,477995841999477 )
BMC Med Inform Decis Mak - GliomaPredict: a clinically useful tool for assigning glioma patients to specific molecular subtypes. ( 0,477954097117148 )
J Am Med Inform Assoc - An ontology-driven, diagnostic modeling system. ( 0,477894436286412 )
Lifetime Data Anal - A class of semiparametric transformation models for survival data with a cured proportion. ( 0,47473667942565 )
IEEE Trans Image Process - A marked point process for modeling lidar waveforms. ( 0,474258661020393 )
J Biomed Inform - Developing an expert panel process to refine health outcome definitions in observational data. ( 0,470090060576122 )
J Biomed Inform - TURF: toward a unified framework of EHR usability. ( 0,469305940432734 )
Lifetime Data Anal - Semiparametric analysis of recurrent events: artificial censoring, truncation, pairwise estimation and inference. ( 0,468509480999956 )
Int J Neural Syst - Principal polynomial analysis. ( 0,46807299833294 )
IEEE Trans Image Process - A Kullback-Leibler divergence approach to blind image restoration. ( 0,467936847482643 )
IEEE Trans Image Process - Measuring the quality of quality measures. ( 0,466611123904149 )
Int J Comput Assist Radiol Surg - The LiverSurgeryTrainer: training of computer-based planning in liver resection surgery. ( 0,46501990951304 )
Comput Math Methods Med - A computationally efficient, exploratory approach to brain connectivity incorporating false discovery rate control, a priori knowledge, and group inference. ( 0,464730534412412 )
Comput. Biol. Med. - The impact of fine-tuning of optical recognition system on database reliability. ( 0,464042722330766 )
J Med Syst - Privacy and security in mobile health apps: a review and recommendations. ( 0,4625 )
J Chem Inf Model - Characterizing the strength of individual hydrogen bonds in DNA base pairs. ( 0,4623665935557 )
Med Decis Making - Assessing personalized medicines in Australia: a national framework for reviewing codependent technologies. ( 0,46178481512031 )
Med Biol Eng Comput - Binary optimization for source localization in the inverse problem of ECG. ( 0,461684845415387 )
IEEE Trans Image Process - On preserving original variables in Bayesian PCA with application to image analysis. ( 0,460798697594848 )
Comput Methods Programs Biomed - PopED: an extended, parallelized, nonlinear mixed effects models optimal design tool. ( 0,460380998033061 )
Comput Math Methods Med - Segmentation of intensity inhomogeneous brain MR images using active contours. ( 0,459717947563256 )
Int J Med Inform - A novel report generation approach for medical applications: the SISDS methodology and its applications. ( 0,459398977503789 )
Int J Comput Assist Radiol Surg - A method for segmentation of dental implants and crestal bone. ( 0,458971236680773 )
Comput Methods Programs Biomed - A multi-task learning approach for the extraction of single-trial evoked potentials. ( 0,458798465282995 )
Spat Spatiotemporal Epidemiol - The use of sampling weights in Bayesian hierarchical models for small area estimation. ( 0,458698482041524 )
Brief. Bioinformatics - From miRNA regulation to miRNA-TF co-regulation: computational approaches and challenges. ( 0,457935820197002 )
Artif Intell Med - Classification integration and reclassification using constraint databases. ( 0,457816909846771 )
J Clin Monit Comput - Automatic control of the NMB level in general anaesthesia with a switching total system mass control strategy. ( 0,457403907237855 )
Lifetime Data Anal - Efficient estimation of the distribution of time to composite endpoint when some endpoints are only partially observed. ( 0,456697974645302 )
AMIA Annu Symp Proc - Online deviation detection for medical processes. ( 0,456460474064909 )
Med Biol Eng Comput - A poisson process model for hip fracture risk. ( 0,456414884102708 )
Comput Methods Programs Biomed - A web-based system for clinical decision support and knowledge maintenance for deterioration monitoring of hemato-oncological patients. ( 0,45619988497732 )
Artif Intell Med - A quantifier-based fuzzy classification system for breast cancer patients. ( 0,456108635874501 )
Artif Intell Med - Artificial intelligence framework for simulating clinical decision-making: a Markov decision process approach. ( 0,455854388012662 )
Brief. Bioinformatics - CaliBayes and BASIS: integrated tools for the calibration, simulation and storage of biological simulation models. ( 0,45370102344415 )
IEEE Trans Image Process - Tomographic reconstruction of gated data acquisition using DFT basis functions. ( 0,453479419295484 )
J Am Med Inform Assoc - Comparison of two kinds of interface, based on guided navigation or usability principles, for improving the adoption of computerized decision support systems: application to the prescription of antibiotics. ( 0,452712101368865 )
J Chem Inf Model - XenoSite: accurately predicting CYP-mediated sites of metabolism with neural networks. ( 0,452437010113342 )
IEEE Trans Vis Comput Graph - Property and Lighting Manipulations for Static Volume Stylization Using a Painting Metaphor. ( 0,452331273031901 )
Methods Inf Med - Objectifying user critique. A means of continuous quality assurance for physician discharge letter composition. ( 0,45139230660292 )
BMC Med Inform Decis Mak - User needs elicitation via analytic hierarchy process (AHP). A case study on a Computed Tomography (CT) scanner. ( 0,450432967524991 )
Comput Methods Programs Biomed - Whole-body isometric force/torque measurements for functional assessment in neuro-rehabilitation: user interface and data pre-processing techniques. ( 0,450387277533006 )
Int J Med Inform - LERM (Logical Elements Rule Method): a method for assessing and formalizing clinical rules for decision support. ( 0,450357490765432 )
J Biomed Inform - Multi-View Interaction Modelling of human collaboration processes: a business process study of head and neck cancer care in a Dutch academic hospital. ( 0,449030766867833 )
Comput Methods Programs Biomed - SAS macro programs for geographically weighted generalized linear modeling with spatial point data: applications to health research. ( 0,448751049640816 )
Artif Intell Med - Fuzzy Arden Syntax: A fuzzy programming language for medicine. ( 0,448326678000915 )
J Med Syst - Enhanced UHF RFID tags for drug tracing. ( 0,447954629306452 )
J Biomed Inform - From expert-derived user needs to user-perceived ease of use and usefulness: a two-phase mixed-methods evaluation framework. ( 0,447458158288352 )
IEEE Trans Image Process - Hyperconnections and hierarchical representations for grayscale and multiband image processing. ( 0,447086344063661 )
BMC Med Inform Decis Mak - Presenting quantitative information about decision outcomes: a risk communication primer for patient decision aid developers. ( 0,446026440890903 )
J Biomed Inform - Incorporation of expert variability into breast cancer treatment recommendation in designing clinical protocol guided fuzzy rule system models. ( 0,445929603198951 )
IEEE Trans Pattern Anal Mach Intell - Reading 1D Barcodes with Mobile Phones Using Deformable Templates. ( 0,445925893545231 )
IEEE Trans Image Process - A study of multiplicative watermark detection in the contourlet domain using alpha-stable distributions. ( 0,445776807119281 )
IEEE Trans Vis Comput Graph - Importance Driven Environment Map Sampling. ( 0,445181086636134 )
Artif Intell Med - Performance of a dermoscopy-based computer vision system for the diagnosis of pigmented skin lesions compared with visual evaluation by experienced dermatologists. ( 0,444500444500667 )
J Chem Inf Model - Improving protocols for protein mapping through proper comparison to crystallography data. ( 0,444478318492315 )
J Med Syst - Design of a fuzzy-based decision support system for coronary heart disease diagnosis. ( 0,444448609009307 )
J Am Med Inform Assoc - Adoption of a wiki within a large internal medicine residency program: a 3-year experience. ( 0,443829286773265 )
Comput Methods Programs Biomed - The extensible open-source rigid and affine image registration module of the Medical Imaging Interaction Toolkit (MITK). ( 0,443820309453844 )
J Med Syst - Evaluation of computerized physician order entry system-a satisfaction survey in Taiwan. ( 0,443606975367134 )
Int J Comput Assist Radiol Surg - The Medical Imaging Interaction Toolkit: challenges and advances : 10 years of open-source development. ( 0,44350872806733 )
Neural Comput - The basal ganglia optimize decision making over general perceptual hypotheses. ( 0,44289968471309 )
J Clin Monit Comput - Closed loop mechanical ventilation. ( 0,44263136810739 )
IEEE Trans Vis Comput Graph - Translucent Radiosity: Efficiently Combining Diffuse Inter-reflection and Subsurface Scattering. ( 0,442442432263979 )
Med Biol Eng Comput - Foot trajectory approximation using the pendulum model of walking. ( 0,442390553368177 )
BMC Med Inform Decis Mak - Quality of human-computer interaction--results of a national usability survey of hospital-IT in Germany. ( 0,442334400903007 )
IEEE J Biomed Health Inform - An ultrasonographic risk score for detecting symptomatic carotid atherosclerotic plaques. ( 0,442067796082261 )
Comput. Biol. Med. - Fuzzy logic based anaesthesia monitoring systems for the detection of absolute hypovolaemia. ( 0,441958160892171 )
IEEE Trans Neural Netw Learn Syst - Two-Stage Regularized Linear Discriminant Analysis for 2-D Data. ( 0,440581976517009 )