Comput Methods Programs Biomed - Debris removal in Pap-smear images.

Tópicos

{ detect(2391) sensit(1101) algorithm(908) }
{ sampl(1606) size(1419) use(1276) }
{ can(774) often(719) complex(702) }
{ model(2220) cell(1177) simul(1124) }
{ howev(809) still(633) remain(590) }
{ implement(1333) system(1263) develop(1122) }
{ process(1125) use(805) approach(778) }
{ featur(3375) classif(2383) classifi(1994) }
{ imag(2675) segment(2577) method(1081) }
{ surgeri(1148) surgic(1085) robot(1054) }
{ algorithm(1844) comput(1787) effici(935) }
{ method(1557) propos(1049) approach(1037) }
{ first(2504) two(1366) second(1323) }
{ analysi(2126) use(1163) compon(1037) }
{ method(1969) cluster(1462) data(1082) }
{ sequenc(1873) structur(1644) protein(1328) }
{ method(1219) similar(1157) match(930) }
{ patient(2315) diseas(1263) diabet(1191) }
{ motion(1329) object(1292) video(1091) }
{ framework(1458) process(801) describ(734) }
{ chang(1828) time(1643) increas(1301) }
{ care(1570) inform(1187) nurs(1089) }
{ risk(3053) factor(974) diseas(938) }
{ compound(1573) activ(1297) structur(1058) }
{ ehr(2073) health(1662) electron(1139) }
{ drug(1928) target(777) effect(648) }
{ measur(2081) correl(1212) valu(896) }
{ problem(2511) optim(1539) algorithm(950) }
{ concept(1167) ontolog(924) domain(897) }
{ clinic(1479) use(1117) guidelin(835) }
{ data(1714) softwar(1251) tool(1186) }
{ system(1050) medic(1026) inform(1018) }
{ visual(1396) interact(850) tool(830) }
{ cost(1906) reduc(1198) effect(832) }
{ data(3008) multipl(1320) sourc(1022) }
{ cancer(2502) breast(956) screen(824) }
{ use(1733) differ(960) four(931) }
{ method(2212) result(1239) propos(1039) }
{ model(3404) distribut(989) bayesian(671) }
{ imag(1947) propos(1133) code(1026) }
{ data(1737) use(1416) pattern(1282) }
{ inform(2794) health(2639) internet(1427) }
{ system(1976) rule(880) can(841) }
{ imag(1057) registr(996) error(939) }
{ bind(1733) structur(1185) ligand(1036) }
{ imag(2830) propos(1344) filter(1198) }
{ network(2748) neural(1063) input(814) }
{ take(945) account(800) differ(722) }
{ studi(2440) review(1878) systemat(933) }
{ assess(1506) score(1403) qualiti(1306) }
{ treatment(1704) effect(941) patient(846) }
{ error(1145) method(1030) estim(1020) }
{ learn(2355) train(1041) set(1003) }
{ extract(1171) text(1153) clinic(932) }
{ design(1359) user(1324) use(1319) }
{ control(1307) perform(991) simul(935) }
{ general(901) number(790) one(736) }
{ method(984) reconstruct(947) comput(926) }
{ search(2224) databas(1162) retriev(909) }
{ featur(1941) imag(1645) propos(1176) }
{ case(1353) use(1143) diagnosi(1136) }
{ data(3963) clinic(1234) research(1004) }
{ studi(1410) differ(1259) use(1210) }
{ perform(999) metric(946) measur(919) }
{ research(1085) discuss(1038) issu(1018) }
{ import(1318) role(1303) understand(862) }
{ model(2341) predict(2261) use(1141) }
{ perform(1367) use(1326) method(1137) }
{ studi(1119) effect(1106) posit(819) }
{ blood(1257) pressur(1144) flow(957) }
{ spatial(1525) area(1432) region(1030) }
{ record(1888) medic(1808) patient(1693) }
{ health(3367) inform(1360) care(1135) }
{ model(3480) simul(1196) paramet(876) }
{ monitor(1329) mobil(1314) devic(1160) }
{ state(1844) use(1261) util(961) }
{ research(1218) medic(880) student(794) }
{ patient(2837) hospit(1953) medic(668) }
{ model(2656) set(1616) predict(1553) }
{ data(2317) use(1299) case(1017) }
{ age(1611) year(1155) adult(843) }
{ medic(1828) order(1363) alert(1069) }
{ signal(2180) analysi(812) frequenc(800) }
{ group(2977) signific(1463) compar(1072) }
{ gene(2352) biolog(1181) express(1162) }
{ intervent(3218) particip(2042) group(1664) }
{ activ(1138) subject(705) human(624) }
{ time(1939) patient(1703) rate(768) }
{ patient(1821) servic(1111) care(1106) }
{ use(2086) technolog(871) perceiv(783) }
{ can(981) present(881) function(850) }
{ health(1844) social(1437) communiti(874) }
{ structur(1116) can(940) graph(676) }
{ high(1669) rate(1365) level(1280) }
{ use(976) code(926) identifi(902) }
{ result(1111) use(1088) new(759) }
{ survey(1388) particip(1329) question(1065) }
{ estim(2440) model(1874) function(577) }
{ decis(3086) make(1611) patient(1517) }
{ activ(1452) weight(1219) physic(1104) }

Resumo

Since its introduction in the 1940s the Pap-smear test has helped reduce the incidence of cervical cancer dramatically in countries where regular screening is standard. The automation of this procedure is an open problem that has been ongoing for over fifty years without reaching satisfactory results. Existing systems are discouragingly expensive and yet they are only able to make a correct distinction between normal and abnormal samples in a fraction of cases. Therefore, they are limited to acting as support for the cytotechnicians as they perform their manual screening. The main reason for the current limitations is that the automated systems struggle to overcome the complexity of the cell structures. Samples are covered in artefacts such as blood cells, overlapping and folded cells, and bacteria, that hamper the segmentation processes and generate large number of suspicious objects. The classifiers designed to differentiate between normal cells and pre-cancerous cells produce unpredictable results when classifying artefacts. In this paper, we propose a sequential classification scheme focused on removing unwanted objects, debris, from an initial segmentation result, intended to be run before the actual normal/abnormal classifier. The method has been evaluated using three separate datasets obtained from cervical samples prepared using both the standard Pap-smear approach as well as the more recent liquid based cytology sample preparation technique. We show success in removing more than 99% of the debris without loosing more than around one percent of the epithelial cells detected by the segmentation process.

Resumo Limpo

sinc introduct s papsmear test help reduc incid cervic cancer dramat countri regular screen standard autom procedur open problem ongo fifti year without reach satisfactori result exist system discourag expens yet abl make correct distinct normal abnorm sampl fraction case therefor limit act support cytotechnician perform manual screen main reason current limit autom system struggl overcom complex cell structur sampl cover artefact blood cell overlap fold cell bacteria hamper segment process generat larg number suspici object classifi design differenti normal cell precancer cell produc unpredict result classifi artefact paper propos sequenti classif scheme focus remov unwant object debri initi segment result intend run actual normalabnorm classifi method evalu use three separ dataset obtain cervic sampl prepar use standard papsmear approach well recent liquid base cytolog sampl prepar techniqu show success remov debri without loos around one percent epitheli cell detect segment process

Resumos Similares

Comput. Biol. Med. - Automatic detection of lung nodules in CT datasets based on stable 3D mass-spring models. ( 0,62818450476679 )
Comput Math Methods Med - Smart spotting of pulmonary TB cavities using CT images. ( 0,62369580075657 )
J. Med. Internet Res. - FluBreaks: early epidemic detection from Google flu trends. ( 0,61390309154359 )
Comput Methods Programs Biomed - Automated detection of microaneurysms using scale-adapted blob analysis and semi-supervised learning. ( 0,613697048015413 )
J Am Med Inform Assoc - A benchmark comparison of deterministic and probabilistic methods for defining manual review datasets in duplicate records reconciliation. ( 0,604064034351917 )
J Clin Monit Comput - Detection of endobronchial intubation by monitoring the CO2 level above the endotracheal cuff. ( 0,602618081452392 )
Med Biol Eng Comput - Quasi real-time gait event detection using shank-attached gyroscopes. ( 0,600413783019617 )
Comput Methods Programs Biomed - A review of thresholding strategies applied to human chromosome segmentation. ( 0,598247306225092 )
IEEE Trans Image Process - Fast video shot boundary detection based on SVD and pattern matching. ( 0,598091619258033 )
Comput. Biol. Med. - A statistical approach for determination of time plane features from digitized ECG. ( 0,596706171312441 )
Comput Methods Programs Biomed - Blood vessel segmentation methodologies in retinal images--a survey. ( 0,59614959961604 )
Comput. Biol. Med. - Myocardial border detection from ventriculograms using support vector machines and real-coded genetic algorithms. ( 0,592011011787208 )
Comput Methods Programs Biomed - A method for corneal nerves automatic segmentation and morphometric analysis. ( 0,590311698061458 )
IEEE J Biomed Health Inform - Automatic identification and classification of muscle spasms in long-term EMG recordings. ( 0,590247023589578 )
Comput. Biol. Med. - Classification and retrieval on macroinvertebrate image databases. ( 0,587506899533587 )
Int J Neural Syst - Automated seizure detection using EKG. ( 0,582136718460882 )
IEEE Trans Pattern Anal Mach Intell - Robust Text Detection in Natural Scene Images. ( 0,581072394869754 )
Comput Methods Programs Biomed - Unsupervised skin lesions border detection via two-dimensional image analysis. ( 0,576428295231749 )
Int J Comput Assist Radiol Surg - Detection and quantification of intracerebral and intraventricular hemorrhage from computed tomography images with adaptive thresholding and case-based reasoning. ( 0,572445142215517 )
AMIA Annu Symp Proc - Optimized dual threshold entity resolution for electronic health record databases--training set size and active learning. ( 0,571372327538737 )
IEEE Trans Image Process - Lightweight detection of additive watermarking in the DWT-domain. ( 0,566817628329611 )
Comput Math Methods Med - Higuchi fractal properties of onset epilepsy electroencephalogram. ( 0,565264982169445 )
Artif Intell Med - Leucocyte classification for leukaemia detection using image processing techniques. ( 0,562466811225991 )
Comput Methods Programs Biomed - Influence of QRS complex detection errors on entropy algorithms. Application to heart rate variability discrimination. ( 0,560716000608609 )
IEEE J Biomed Health Inform - Robust and sensitive video motion detection for sleep analysis. ( 0,560359383466242 )
Comput Math Methods Med - Automatic detection and quantification of WBCs and RBCs using iterative structured circle detection algorithm. ( 0,558694089910791 )
Comput Methods Programs Biomed - Automated detection of exudates and macula for grading of diabetic macular edema. ( 0,55839796646816 )
Med Biol Eng Comput - Analysis of retinal fundus images for grading of diabetic retinopathy severity. ( 0,557837919333522 )
BMC Med Inform Decis Mak - Outbreak detection algorithms for seasonal disease data: a case study using Ross River virus disease. ( 0,555362383821594 )
Comput. Biol. Med. - Automated detection of the osseous acetabular rim using three-dimensional models of the pelvis. ( 0,554964915240533 )
Int J Comput Assist Radiol Surg - Hybrid method for the detection of pulmonary nodules using positron emission tomography/computed tomography: a preliminary study. ( 0,55376037306653 )
Comput Methods Programs Biomed - Automated detection of proliferative diabetic retinopathy using a modified line operator and dual classification. ( 0,553208555347277 )
BMC Med Inform Decis Mak - Automated systems to identify relevant documents in product risk management. ( 0,546587073042413 )
J. Comput. Biol. - Feature detection with controlled error rates in LC/MS images. ( 0,544638506455121 )
IEEE Trans Pattern Anal Mach Intell - Automatic and Accurate Shadow Detection using Near-Infrared Information. ( 0,543776290522969 )
Int J Neural Syst - Kernel collaborative representation-based automatic seizure detection in intracranial EEG. ( 0,542816090443962 )
Med Biol Eng Comput - Abnormal localization of immature precursors (ALIP) detection for early prediction of acute myelocytic leukemia (AML) relapse. ( 0,540844776173479 )
Comput Methods Programs Biomed - Automatic multi-modal intelligent seizure acquisition (MISA) system for detection of motor seizures from electromyographic data and motion data. ( 0,540477406344322 )
Int J Neural Syst - Multi-instance dictionary learning for detecting abnormal events in surveillance videos. ( 0,539511732895598 )
J Am Med Inform Assoc - Phenotyping for patient safety: algorithm development for electronic health record based automated adverse event and medical error detection in neonatal intensive care. ( 0,538166170563946 )
Artif Intell Med - Automatic detection of solitary lung nodules using quality threshold clustering, genetic algorithm and diversity index. ( 0,537915136500182 )
Comput Methods Programs Biomed - Accurate detection of blood vessels improves the detection of exudates in color fundus images. ( 0,537628158842317 )
J Med Syst - An improved retinal vessel segmentation method based on high level features for pathological images. ( 0,53708686323642 )
Comput Biol Chem - Effect of sampling on the extent and accuracy of the inferred genetic history of recombining genome. ( 0,536726388553906 )
Comput. Biol. Med. - Automatic exudate detection by fusing multiple active contours and regionwise classification. ( 0,535853438382948 )
Comput Methods Programs Biomed - An automated decision-support system for non-proliferative diabetic retinopathy disease based on MAs and HAs detection. ( 0,534720408308117 )
Med Biol Eng Comput - GPU-based real-time detection and analysis of biological targets using solid-state nanopores. ( 0,534637392128127 )
IEEE Trans Image Process - Environmentally robust motion detection for video surveillance. ( 0,531229091976 )
Comput Math Methods Med - Automatic segmentation and measurement of vasculature in retinal fundus images using probabilistic formulation. ( 0,530777628088565 )
IEEE J Biomed Health Inform - Fast and adaptive detection of pulmonary nodules in thoracic CT images using a hierarchical vector quantization scheme. ( 0,530544140569798 )
Comput. Biol. Med. - Early detection of epileptic seizures based on parameter identification of neural mass model. ( 0,529906973710688 )
J Med Syst - Detection and localization of myocardial infarction using K-nearest neighbor classifier. ( 0,528310123905678 )
Comput. Biol. Med. - A correlation analysis-based detection and delineation of ECG characteristic events using template waveforms extracted by ensemble averaging of clustered heart cycles. ( 0,527412175556973 )
J Med Syst - Bleeding detection in Wireless Capsule Endoscopy based on Probabilistic Neural Network. ( 0,527338164679122 )
Res Synth Methods - Methods for the joint meta-analysis of multiple tests. ( 0,52664802456137 )
Comput. Biol. Med. - Towards a social and context-aware multi-sensor fall detection and risk assessment platform. ( 0,526509169334979 )
J Am Med Inform Assoc - Use of computerized algorithm to identify individuals in need of testing for celiac disease. ( 0,525994757629125 )
Int J Comput Assist Radiol Surg - Automated MR morphometry to predict Alzheimer's disease in mild cognitive impairment. ( 0,52519599606202 )
AMIA Annu Symp Proc - Methods for identifying suicide or suicidal ideation in EHRs. ( 0,525058869018827 )
Artif Intell Med - Using a multi-agent system approach for microaneurysm detection in fundus images. ( 0,524465129580919 )
AMIA Annu Symp Proc - Automatic Prediction of Conversion from Mild Cognitive Impairment to Probable Alzheimer's Disease using Structural Magnetic Resonance Imaging. ( 0,524169822615175 )
J Med Syst - Field programmable gate array based fuzzy neural signal processing system for differential diagnosis of QRS complex tachycardia and tachyarrhythmia in noisy ECG signals. ( 0,521670499284417 )
J Am Med Inform Assoc - Adjusting outbreak detection algorithms for surveillance during epidemic and non-epidemic periods. ( 0,521241425863697 )
Comput Methods Programs Biomed - Automated pulmonary nodule detection based on three-dimensional shape-based feature descriptor. ( 0,520791490926971 )
Comput. Biol. Med. - A user-operated test of suprathreshold acuity in noise for adult hearing screening: The SUN (Speech Understanding in Noise) test. ( 0,520779508994932 )
IEEE Trans Image Process - Automatic virus particle selection--the entropy approach. ( 0,519198709481292 )
Comput Biol Chem - ProteinLasso: A Lasso regression approach to protein inference problem in shotgun proteomics. ( 0,518685279005284 )
IEEE Trans Pattern Anal Mach Intell - Online Learning and Sequential Anomaly Detection in Trajectories. ( 0,517921870025758 )
Comput. Biol. Med. - Automatic identification of fetal breathing movements in fetal RR interval time series. ( 0,512879784297249 )
AMIA Annu Symp Proc - Computer surveillance of patients at high risk for and with venous thromboembolism. ( 0,512450832357194 )
Int J Comput Assist Radiol Surg - Object-based analysis of CT images for automatic detection and segmentation of hypodense liver lesions. ( 0,511697467653316 )
Med Biol Eng Comput - CFS-SMO based classification of breast density using multiple texture models. ( 0,510285114650859 )
IEEE Trans Pattern Anal Mach Intell - Video Event Detection: From Subvolume Localization To Spatio-Temporal Path Search. ( 0,509940798744701 )
Comput. Biol. Med. - Detection and classification of retinal lesions for grading of diabetic retinopathy. ( 0,509775293135406 )
Int J Comput Assist Radiol Surg - Combination of computer-aided detection algorithms for automatic lung nodule identification. ( 0,50898310373707 )
Med Decis Making - A framework for evaluating markers used to select patient treatment. ( 0,506447123619339 )
J Clin Monit Comput - Pulse oximetry saturation patterns detect repetitive reductions in airflow. ( 0,504889060298226 )
IEEE Trans Pattern Anal Mach Intell - Understanding Blind Deconvolution Algorithms. ( 0,503130758532162 )
IEEE Trans Image Process - Unified framework for automated iris segmentation using distantly acquired face images. ( 0,502354793866308 )
Int J Med Inform - Validating an ontology-based algorithm to identify patients with type 2 diabetes mellitus in electronic health records. ( 0,502199460579105 )
BMC Med Inform Decis Mak - Evaluation of syndromic algorithms for detecting patients with potentially transmissible infectious diseases based on computerised emergency-department data. ( 0,501771699034408 )
J Med Syst - Three-dimensional SVM with latent variable: application for detection of lung lesions in CT images. ( 0,501032653041066 )
J Biomed Inform - Computer-aided detection of breast cancer on mammograms: a swarm intelligence optimized wavelet neural network approach. ( 0,500641103034603 )
Int J Comput Assist Radiol Surg - Diffusion tensor tractography of normal facial and vestibulocochlear nerves. ( 0,500142442503292 )
IEEE Trans Image Process - Dynamically removing false features in pyramidal lucas-kanade registration. ( 0,500061335754743 )
Methods Inf Med - Detection algorithm for single motor unit firing in surface EMG of the trapezius muscle. ( 0,499413283429022 )
Artif Intell Med - Detecting rare events using extreme value statistics applied to epileptic convulsions in children. ( 0,49906535157214 )
Comput Methods Programs Biomed - Human fall detection on embedded platform using depth maps and wireless accelerometer. ( 0,498427856736779 )
Comput. Biol. Med. - Feasibility of quantitative analysis of regional left ventricular function in the post-infarct mouse by magnetic resonance imaging with retrospective gating. ( 0,498069570833502 )
BMC Med Inform Decis Mak - Adverse drug events with hyperkalaemia during inpatient stays: evaluation of an automated method for retrospective detection in hospital databases. ( 0,497519553472117 )
Comput Math Methods Med - Power and stability properties of resampling-based multiple testing procedures with applications to gene oncology studies. ( 0,496866143257717 )
Comput Methods Programs Biomed - Detection of heartbeat and respiration from optical interferometric signal by using wavelet transform. ( 0,496114101760528 )
Comput. Biol. Med. - Automatic segmentation of lung nodules with growing neural gas and support vector machine. ( 0,495649283692647 )
J Biomed Inform - Predictive combinations of monitor alarms preceding in-hospital code blue events. ( 0,495513132042484 )
Neural Comput - A multiscale correlation of wavelet coefficients approach to spike detection. ( 0,495502764711165 )
J Med Syst - Compressed ECG biometric: a fast, secured and efficient method for identification of CVD patient. ( 0,495259947613416 )
J Biomed Inform - Automation of a high risk medication regime algorithm in a home health care population. ( 0,494753120198785 )
Brief. Bioinformatics - Bioinformatics tools and challenges in structural analysis of lipidomics MS/MS data. ( 0,494590643699786 )
Med Decis Making - A concise equation that captures the essential elements of one-way sensitivity analyses in health economic models. ( 0,493683645060754 )
Comput Math Methods Med - A fuzzy model to interpret data of drive performances from patients with sleep deprivation. ( 0,493246716724751 )