Comput Methods Programs Biomed - A review of thresholding strategies applied to human chromosome segmentation.

Tópicos

{ imag(2675) segment(2577) method(1081) }
{ detect(2391) sensit(1101) algorithm(908) }
{ structur(1116) can(940) graph(676) }
{ first(2504) two(1366) second(1323) }
{ analysi(2126) use(1163) compon(1037) }
{ can(774) often(719) complex(702) }
{ take(945) account(800) differ(722) }
{ surgeri(1148) surgic(1085) robot(1054) }
{ howev(809) still(633) remain(590) }
{ perform(999) metric(946) measur(919) }
{ spatial(1525) area(1432) region(1030) }
{ estim(2440) model(1874) function(577) }
{ featur(3375) classif(2383) classifi(1994) }
{ motion(1329) object(1292) video(1091) }
{ data(2317) use(1299) case(1017) }
{ time(1939) patient(1703) rate(768) }
{ can(981) present(881) function(850) }
{ high(1669) rate(1365) level(1280) }
{ imag(2830) propos(1344) filter(1198) }
{ patient(2315) diseas(1263) diabet(1191) }
{ studi(2440) review(1878) systemat(933) }
{ learn(2355) train(1041) set(1003) }
{ extract(1171) text(1153) clinic(932) }
{ control(1307) perform(991) simul(935) }
{ search(2224) databas(1162) retriev(909) }
{ case(1353) use(1143) diagnosi(1136) }
{ risk(3053) factor(974) diseas(938) }
{ research(1085) discuss(1038) issu(1018) }
{ system(1050) medic(1026) inform(1018) }
{ import(1318) role(1303) understand(862) }
{ model(2341) predict(2261) use(1141) }
{ health(3367) inform(1360) care(1135) }
{ ehr(2073) health(1662) electron(1139) }
{ state(1844) use(1261) util(961) }
{ gene(2352) biolog(1181) express(1162) }
{ data(3008) multipl(1320) sourc(1022) }
{ drug(1928) target(777) effect(648) }
{ implement(1333) system(1263) develop(1122) }
{ process(1125) use(805) approach(778) }
{ model(3404) distribut(989) bayesian(671) }
{ imag(1947) propos(1133) code(1026) }
{ data(1737) use(1416) pattern(1282) }
{ inform(2794) health(2639) internet(1427) }
{ system(1976) rule(880) can(841) }
{ measur(2081) correl(1212) valu(896) }
{ imag(1057) registr(996) error(939) }
{ bind(1733) structur(1185) ligand(1036) }
{ sequenc(1873) structur(1644) protein(1328) }
{ method(1219) similar(1157) match(930) }
{ network(2748) neural(1063) input(814) }
{ assess(1506) score(1403) qualiti(1306) }
{ treatment(1704) effect(941) patient(846) }
{ framework(1458) process(801) describ(734) }
{ problem(2511) optim(1539) algorithm(950) }
{ error(1145) method(1030) estim(1020) }
{ chang(1828) time(1643) increas(1301) }
{ concept(1167) ontolog(924) domain(897) }
{ clinic(1479) use(1117) guidelin(835) }
{ algorithm(1844) comput(1787) effici(935) }
{ method(1557) propos(1049) approach(1037) }
{ data(1714) softwar(1251) tool(1186) }
{ design(1359) user(1324) use(1319) }
{ model(2220) cell(1177) simul(1124) }
{ care(1570) inform(1187) nurs(1089) }
{ general(901) number(790) one(736) }
{ method(984) reconstruct(947) comput(926) }
{ featur(1941) imag(1645) propos(1176) }
{ data(3963) clinic(1234) research(1004) }
{ studi(1410) differ(1259) use(1210) }
{ visual(1396) interact(850) tool(830) }
{ compound(1573) activ(1297) structur(1058) }
{ perform(1367) use(1326) method(1137) }
{ studi(1119) effect(1106) posit(819) }
{ blood(1257) pressur(1144) flow(957) }
{ record(1888) medic(1808) patient(1693) }
{ model(3480) simul(1196) paramet(876) }
{ monitor(1329) mobil(1314) devic(1160) }
{ research(1218) medic(880) student(794) }
{ patient(2837) hospit(1953) medic(668) }
{ model(2656) set(1616) predict(1553) }
{ age(1611) year(1155) adult(843) }
{ medic(1828) order(1363) alert(1069) }
{ signal(2180) analysi(812) frequenc(800) }
{ cost(1906) reduc(1198) effect(832) }
{ group(2977) signific(1463) compar(1072) }
{ sampl(1606) size(1419) use(1276) }
{ intervent(3218) particip(2042) group(1664) }
{ activ(1138) subject(705) human(624) }
{ patient(1821) servic(1111) care(1106) }
{ use(2086) technolog(871) perceiv(783) }
{ health(1844) social(1437) communiti(874) }
{ cancer(2502) breast(956) screen(824) }
{ use(976) code(926) identifi(902) }
{ use(1733) differ(960) four(931) }
{ result(1111) use(1088) new(759) }
{ survey(1388) particip(1329) question(1065) }
{ decis(3086) make(1611) patient(1517) }
{ activ(1452) weight(1219) physic(1104) }
{ method(1969) cluster(1462) data(1082) }
{ method(2212) result(1239) propos(1039) }

Resumo

Karyotype analysis is a widespread procedure in cytogenetics to assess the presence of genetic defects by the visualization of the structure of chromosomes. The procedure is lengthy and repetitive and an effective automatic analysis would greatly help the cytogeneticist routine work. Still, automatic segmentation and the full disentangling of chromosomes are open issues. The first step in every automatic procedure is the thresholding step, which detect blobs that represent either single chromosomes or clusters of chromosomes. The better the thresholding step, the easier is the subsequent disentanglement of chromosome clusters into single entities. We implemented eleven thresholding methods, i.e. the ones that appear in the literature as the best performers, and compared their performance in segmenting chromosomes and chromosome clusters in cytogenetic Q-band images. The images are affected by the presence of hyper- or hypo-fluorescent regions and by a contrast variability between the stained chromosomes and the background. A thorough analysis of the results highlights that, although every single algorithm shows peculiar strong/weak points, Adaptive Threshold and Region Based Level Set have the overall best performance. In order to provide the scientific community with a public dataset, the data and manual segmentation used in this paper are available for public download at http://bioimlab.dei.unipd.it.

Resumo Limpo

karyotyp analysi widespread procedur cytogenet assess presenc genet defect visual structur chromosom procedur lengthi repetit effect automat analysi great help cytogeneticist routin work still automat segment full disentangl chromosom open issu first step everi automat procedur threshold step detect blob repres either singl chromosom cluster chromosom better threshold step easier subsequ disentangl chromosom cluster singl entiti implement eleven threshold method ie one appear literatur best perform compar perform segment chromosom chromosom cluster cytogenet qband imag imag affect presenc hyper hypofluoresc region contrast variabl stain chromosom background thorough analysi result highlight although everi singl algorithm show peculiar strongweak point adapt threshold region base level set overal best perform order provid scientif communiti public dataset data manual segment use paper avail public download httpbioimlabdeiunipdit

Resumos Similares

Comput Methods Programs Biomed - Accurate detection of blood vessels improves the detection of exudates in color fundus images. ( 0,752679326071888 )
Int J Comput Assist Radiol Surg - Automated liver lesion detection in CT images based on multi-level geometric features. ( 0,747967754516749 )
Comput Methods Programs Biomed - A method for corneal nerves automatic segmentation and morphometric analysis. ( 0,74318853319693 )
Int J Comput Assist Radiol Surg - Object-based analysis of CT images for automatic detection and segmentation of hypodense liver lesions. ( 0,740520185160524 )
Int J Comput Assist Radiol Surg - Spatially adaptive active contours: a semi-automatic tumor segmentation framework. ( 0,73920744855045 )
Comput Methods Programs Biomed - Blood vessel segmentation methodologies in retinal images--a survey. ( 0,732676272799407 )
Med Biol Eng Comput - Automatic detection and segmentation of bovine corpora lutea in ultrasonographic ovarian images using genetic programming and rotation invariant local binary patterns. ( 0,730890971801876 )
Comput Math Methods Med - Automatic segmentation and measurement of vasculature in retinal fundus images using probabilistic formulation. ( 0,729811391097897 )
Comput Methods Programs Biomed - Unsupervised skin lesions border detection via two-dimensional image analysis. ( 0,727587234818688 )
Comput. Biol. Med. - Automatic detection of lung nodules in CT datasets based on stable 3D mass-spring models. ( 0,717328207089297 )
Comput Math Methods Med - Bayesian method with spatial constraint for retinal vessel segmentation. ( 0,705718399267648 )
Comput Methods Programs Biomed - An approach to localize the retinal blood vessels using bit planes and centerline detection. ( 0,705342155152146 )
Int J Comput Assist Radiol Surg - Vertebra identification using template matching modelmp and K-means clustering. ( 0,70099284257552 )
Int J Comput Assist Radiol Surg - Automatic lung segmentation method for MRI-based lung perfusion studies of patients with chronic obstructive pulmonary disease. ( 0,688956806614114 )
Int J Comput Assist Radiol Surg - Detection and quantification of intracerebral and intraventricular hemorrhage from computed tomography images with adaptive thresholding and case-based reasoning. ( 0,68811827779126 )
Methods Inf Med - Automatic correction of gaps in cerebrovascular segmentations extracted from 3D time-of-flight MRA datasets. ( 0,684108877974054 )
IEEE Trans Image Process - Fast video shot boundary detection based on SVD and pattern matching. ( 0,683865975401945 )
Comput Methods Programs Biomed - Wavelets and fuzzy relational classifiers: a novel diffusion-weighted image analysis system for pediatric metabolic brain diseases. ( 0,682958944739758 )
IEEE Trans Pattern Anal Mach Intell - Paired Regions for Shadow Detection and Removal. ( 0,680301668077509 )
Comput Methods Programs Biomed - Automatic model-based tracing algorithm for vessel segmentation and diameter estimation. ( 0,678559984339471 )
Int J Comput Assist Radiol Surg - Automatic definition of the central-chest lymph-node stations. ( 0,678327192333933 )
IEEE Trans Image Process - Connectivity-enforcing Hough transform for the robust extraction of line segments. ( 0,675335596875313 )
J Digit Imaging - Dual-pass feature extraction on human vessel images. ( 0,675033486255193 )
Comput Methods Programs Biomed - A novel method for pulmonary embolism detection in CTA images. ( 0,67418777385414 )
J Med Syst - Automated identification of exudates and optic disc based on inverse surface thresholding. ( 0,672392647302243 )
Comput Methods Programs Biomed - Automated detection of proliferative diabetic retinopathy using a modified line operator and dual classification. ( 0,671771504548604 )
Comput Methods Programs Biomed - Segmentation of pituitary adenoma: a graph-based method vs. a balloon inflation method. ( 0,671227301778281 )
Comput Math Methods Med - Assessment of feasibility to use computer aided texture analysis based tool for parametric images of suspicious lesions in DCE-MR mammography. ( 0,669056472582205 )
Comput Math Methods Med - Diabetic retinopathy grading by digital curvelet transform. ( 0,668637250029928 )
Comput Methods Programs Biomed - Obtaining optic disc center and pixel region by automatic thresholding methods on morphologically processed fundus images. ( 0,662721429608419 )
Comput. Biol. Med. - A review on segmentation of positron emission tomography images. ( 0,662711159851606 )
Comput. Biol. Med. - Automatic brain extraction methods for T1 magnetic resonance images using region labeling and morphological operations. ( 0,659273103579751 )
Comput. Biol. Med. - Refinement of lung nodule candidates based on local geometric shape analysis and Laplacian of Gaussian kernels. ( 0,657982714362683 )
IEEE J Biomed Health Inform - Adaptive shape prior constrained level sets for bladder MR image segmentation. ( 0,656174226479616 )
J Med Syst - Bleeding detection in Wireless Capsule Endoscopy based on Probabilistic Neural Network. ( 0,655689329612809 )
J Med Syst - Accurate automated detection of autism related corpus callosum abnormalities. ( 0,654901064874614 )
Int J Comput Assist Radiol Surg - Delineation of blood vessels in pediatric retinal images using decision trees-based ensemble classification. ( 0,653775716102734 )
IEEE Trans Vis Comput Graph - Supervised Manifold Distance Segmentation. ( 0,648061166882279 )
Int J Comput Assist Radiol Surg - MRI-compatible positioning device for guiding a focused ultrasound system for transrectal treatment of prostate cancer. ( 0,645823927064267 )
Med Biol Eng Comput - Automatic segmentation of brain MR images using an adaptive balloon snake model with fuzzy classification. ( 0,642754455329264 )
Comput. Biol. Med. - Feasibility of quantitative analysis of regional left ventricular function in the post-infarct mouse by magnetic resonance imaging with retrospective gating. ( 0,642379808772314 )
Comput Math Methods Med - A hybrid method for pancreas extraction from CT image based on level set methods. ( 0,641508851009976 )
Comput. Biol. Med. - An automated lung segmentation approach using bidirectional chain codes to improve nodule detection accuracy. ( 0,640489833280363 )
Comput. Biol. Med. - Application of vascular bundle displacement in the optic disc for glaucoma detection using fundus images. ( 0,640242861323856 )
Int J Comput Assist Radiol Surg - Automatic 3D segmentation of individual facial muscles using unlabeled prior information. ( 0,639272235802833 )
Comput. Biol. Med. - Tumor segmentation from computed tomography image data using a probabilistic pixel selection approach. ( 0,638621206702368 )
Comput Methods Programs Biomed - Automatic multiple sclerosis lesion detection in brain MRI by FLAIR thresholding. ( 0,638403421663611 )
Comput Math Methods Med - Constructing benchmark databases and protocols for medical image analysis: diabetic retinopathy. ( 0,637096447902424 )
Comput Methods Programs Biomed - A survey of prostate segmentation methodologies in ultrasound, magnetic resonance and computed tomography images. ( 0,636235743436247 )
Med Biol Eng Comput - Automatic segmentation of the fetal cerebellum on ultrasound volumes, using a 3D statistical shape model. ( 0,633015256738782 )
Comput. Biol. Med. - Lung nodule segmentation and recognition using SVM classifier and active contour modeling: a complete intelligent system. ( 0,632445893106982 )
Comput Math Methods Med - A new multistage medical segmentation method based on superpixel and fuzzy clustering. ( 0,631728228906784 )
J Med Syst - Automated bleeding detection in capsule endoscopy videos using statistical features and region growing. ( 0,63095530115573 )
Comput Math Methods Med - Smart spotting of pulmonary TB cavities using CT images. ( 0,630951241644191 )
Comput. Biol. Med. - Myocardial border detection from ventriculograms using support vector machines and real-coded genetic algorithms. ( 0,630700884215832 )
J Med Syst - An improved retinal vessel segmentation method based on high level features for pathological images. ( 0,629177123920168 )
Med Biol Eng Comput - Interactive segmentation of plexiform neurofibroma tissue: method and preliminary performance evaluation. ( 0,626996681378419 )
IEEE Trans Image Process - VE-LLI-VO: vessel enhancement using local line integrals and variational optimization. ( 0,626057298792329 )
J Med Syst - Automated detection of dark and bright lesions in retinal images for early detection of diabetic retinopathy. ( 0,62406784230936 )
Int J Comput Assist Radiol Surg - Fusion of coronary angiography and stress echocardiography for myocardial viability evaluation. ( 0,623968575343719 )
J Med Syst - Manual refinement system for graph-based segmentation results in the medical domain. ( 0,623759611166305 )
Comput. Biol. Med. - Automatic exudate detection by fusing multiple active contours and regionwise classification. ( 0,623490779076395 )
Comput. Biol. Med. - 3D geometric split-merge segmentation of brain MRI datasets. ( 0,622747888102552 )
Int J Comput Assist Radiol Surg - Determination of the curling behavior of a preformed cochlear implant electrode array. ( 0,622484137508656 )
Int J Comput Assist Radiol Surg - 3D variational brain tumor segmentation using Dirichlet priors on a clustered feature set. ( 0,619930736671011 )
Int J Comput Assist Radiol Surg - Segmentation of iodine brachytherapy implants in fluoroscopy. ( 0,617423650799706 )
Comput. Biol. Med. - Phase-based probabilistic active contour for nerve detection in ultrasound images for regional anesthesia. ( 0,615513658490671 )
Comput Math Methods Med - Multimodal brain-tumor segmentation based on Dirichlet process mixture model with anisotropic diffusion and Markov random field prior. ( 0,61470956168229 )
Int J Comput Assist Radiol Surg - Intraoperative segmentation of iodine and palladium radioactive sources in C-arm images. ( 0,61246749056373 )
Comput Methods Programs Biomed - Gold-standard and improved framework for sperm head segmentation. ( 0,612343508586697 )
Comput. Biol. Med. - An automatic patient-specific seizure onset detection method in intracranial EEG based on incremental nonlinear dimensionality reduction. ( 0,611783876822131 )
Comput Methods Programs Biomed - MARGA: multispectral adaptive region growing algorithm for brain extraction on axial MRI. ( 0,610772443569834 )
Int J Comput Assist Radiol Surg - Automated measurement of mandibular cortical width on dental panoramic radiographs. ( 0,610769259144922 )
IEEE Trans Image Process - Overlapping cell nuclei segmentation using a spatially adaptive active physical model. ( 0,610591449177123 )
IEEE J Biomed Health Inform - A comparison of US- versus MR-based 3-D Prostate Shapes Using Radial Basis Function Interpolation and Statistical Shape Models. ( 0,610212866615615 )
Int J Comput Assist Radiol Surg - Expert-driven label fusion in multi-atlas-based segmentation of the prostate using weighted atlases. ( 0,610145062549344 )
AMIA Annu Symp Proc - Automatic detection of dilated cardiomyopathy in cardiac ultrasound videos. ( 0,610107413218586 )
Sci Data - A high-resolution 7-Tesla fMRI dataset from complex natural stimulation with an audio movie. ( 0,60973940782678 )
Comput. Biol. Med. - Fast segmentation of bone in CT images using 3D adaptive thresholding. ( 0,609354951477056 )
Int J Comput Assist Radiol Surg - Fetal brain volumetry through MRI volumetric reconstruction and segmentation. ( 0,608878230283996 )
IEEE J Biomed Health Inform - Fast and adaptive detection of pulmonary nodules in thoracic CT images using a hierarchical vector quantization scheme. ( 0,608855023571434 )
Int J Comput Assist Radiol Surg - A geodesic deformable model for automatic segmentation of image sequences applied to radiation therapy. ( 0,608715012967039 )
Comput. Biol. Med. - Nearly automated motion artifacts correction between multi breath-hold short-axis and long-axis cine CMR images. ( 0,60858421285372 )
Comput Methods Programs Biomed - Automated detection of microaneurysms using scale-adapted blob analysis and semi-supervised learning. ( 0,608141660674367 )
Int J Comput Assist Radiol Surg - Complete fully automatic model-based segmentation of normal and pathological lymph nodes in CT data. ( 0,608017256691345 )
Int J Comput Assist Radiol Surg - Voxel classification and graph cuts for automated segmentation of pathological periprosthetic hip anatomy. ( 0,607676919905104 )
Med Biol Eng Comput - A fully automated human knee 3D MRI bone segmentation using the ray casting technique. ( 0,60707620240505 )
Comput Math Methods Med - A hybrid approach of using symmetry technique for brain tumor segmentation. ( 0,604881984520356 )
Int J Comput Assist Radiol Surg - Automated aorta segmentation in low-dose chest CT images. ( 0,603592842848285 )
Comput Methods Programs Biomed - Segmentation of ultrasound images of the carotid using RANSAC and cubic splines. ( 0,603066560164748 )
Int J Comput Assist Radiol Surg - Computer-aided nidus segmentation and angiographic characterization of arteriovenous malformations. ( 0,602096490438484 )
Artif Intell Med - Segmentation of nerve fibers using multi-level gradient watershed and fuzzy systems. ( 0,601940921589325 )
Int J Comput Assist Radiol Surg - Automatic left ventricle segmentation in volumetric SPECT data set by variational level set. ( 0,601504647153183 )
Int J Comput Assist Radiol Surg - GPU accelerated segmentation and centerline extraction of tubular structures from medical images. ( 0,600741632791172 )
Int J Comput Assist Radiol Surg - Ameliorating slice gaps in multislice magnetic resonance images: an interpolation scheme. ( 0,599814914019145 )
Comput Math Methods Med - Tract-based Bayesian multivariate analysis of mild traumatic brain injury. ( 0,59869609621715 )
Comput Methods Programs Biomed - Debris removal in Pap-smear images. ( 0,598247306225092 )
IEEE Trans Image Process - Shortest-path constraints for 3D multiobject semiautomatic segmentation via clustering and Graph Cut. ( 0,598173515981735 )
Med Biol Eng Comput - Machine vision-based localization of nucleic and cytoplasmic injection sites on low-contrast adherent cells. ( 0,596536447487347 )
Int J Comput Assist Radiol Surg - Shoulder motion during tennis serve: dynamic and radiological evaluation based on motion capture and magnetic resonance imaging. ( 0,596501003288225 )