Comput Methods Programs Biomed - Geometrical methods for level set based abdominal aortic aneurysm thrombus and outer wall 2D image segmentation.

Tópicos

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Resumo

Abdominal aortic aneurysm (AAA) is a localized dilatation of the aortic wall. Accurate measurements of its geometric characteristics are critical for a reliable estimate of AAA rupture risk. However, current imaging modalities do not provide sufficient contrast to distinguish thrombus from surrounding tissue thus making the task of segmentation quite challenging. The main objective of this paper is to address this problem and accurately extract the thrombus and outer wall boundaries from cross sections of a 3D AAA image data set (CTA). This is achieved by new geometrical methods applied to the boundary curves obtained by a Level Set Method (LSM). Such methods address the problem of leakage of a moving front into sectors of similar intensity and that of the presence of calcifications. The versatility of the methods is tested by creating artificial images which simulate the real cases. Segmentation quality is quantified by comparing the results with a manual segmentation of the slices of ten patient data sets. Sensitivity to the parameter settings and reproducibility are analyzed. This is the first work to our knowledge that utilizes the level set framework to extract both the thrombus and external AAA wall boundaries.

Resumo Limpo

abdomin aortic aneurysm aaa local dilat aortic wall accur measur geometr characterist critic reliabl estim aaa ruptur risk howev current imag modal provid suffici contrast distinguish thrombus surround tissu thus make task segment quit challeng main object paper address problem accur extract thrombus outer wall boundari cross section d aaa imag data set cta achiev new geometr method appli boundari curv obtain level set method lsm method address problem leakag move front sector similar intens presenc calcif versatil method test creat artifici imag simul real case segment qualiti quantifi compar result manual segment slice ten patient data set sensit paramet set reproduc analyz first work knowledg util level set framework extract thrombus extern aaa wall boundari

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