Comput Methods Programs Biomed - An intelligent decision support algorithm for diagnosis of colorectal cancer through serum tumor markers.

Tópicos

{ cancer(2502) breast(956) screen(824) }
{ system(1976) rule(880) can(841) }
{ case(1353) use(1143) diagnosi(1136) }
{ chang(1828) time(1643) increas(1301) }
{ state(1844) use(1261) util(961) }
{ cost(1906) reduc(1198) effect(832) }
{ method(2212) result(1239) propos(1039) }
{ use(1733) differ(960) four(931) }
{ featur(3375) classif(2383) classifi(1994) }
{ general(901) number(790) one(736) }
{ research(1085) discuss(1038) issu(1018) }
{ perform(1367) use(1326) method(1137) }
{ decis(3086) make(1611) patient(1517) }
{ method(1557) propos(1049) approach(1037) }
{ use(2086) technolog(871) perceiv(783) }
{ can(774) often(719) complex(702) }
{ method(1219) similar(1157) match(930) }
{ take(945) account(800) differ(722) }
{ framework(1458) process(801) describ(734) }
{ clinic(1479) use(1117) guidelin(835) }
{ care(1570) inform(1187) nurs(1089) }
{ method(984) reconstruct(947) comput(926) }
{ featur(1941) imag(1645) propos(1176) }
{ system(1050) medic(1026) inform(1018) }
{ data(2317) use(1299) case(1017) }
{ group(2977) signific(1463) compar(1072) }
{ sampl(1606) size(1419) use(1276) }
{ can(981) present(881) function(850) }
{ analysi(2126) use(1163) compon(1037) }
{ survey(1388) particip(1329) question(1065) }
{ estim(2440) model(1874) function(577) }
{ process(1125) use(805) approach(778) }
{ method(1969) cluster(1462) data(1082) }
{ detect(2391) sensit(1101) algorithm(908) }
{ model(3404) distribut(989) bayesian(671) }
{ imag(1947) propos(1133) code(1026) }
{ data(1737) use(1416) pattern(1282) }
{ inform(2794) health(2639) internet(1427) }
{ measur(2081) correl(1212) valu(896) }
{ imag(1057) registr(996) error(939) }
{ bind(1733) structur(1185) ligand(1036) }
{ sequenc(1873) structur(1644) protein(1328) }
{ imag(2830) propos(1344) filter(1198) }
{ network(2748) neural(1063) input(814) }
{ imag(2675) segment(2577) method(1081) }
{ patient(2315) diseas(1263) diabet(1191) }
{ studi(2440) review(1878) systemat(933) }
{ motion(1329) object(1292) video(1091) }
{ assess(1506) score(1403) qualiti(1306) }
{ treatment(1704) effect(941) patient(846) }
{ surgeri(1148) surgic(1085) robot(1054) }
{ problem(2511) optim(1539) algorithm(950) }
{ error(1145) method(1030) estim(1020) }
{ learn(2355) train(1041) set(1003) }
{ concept(1167) ontolog(924) domain(897) }
{ algorithm(1844) comput(1787) effici(935) }
{ extract(1171) text(1153) clinic(932) }
{ data(1714) softwar(1251) tool(1186) }
{ design(1359) user(1324) use(1319) }
{ control(1307) perform(991) simul(935) }
{ model(2220) cell(1177) simul(1124) }
{ search(2224) databas(1162) retriev(909) }
{ howev(809) still(633) remain(590) }
{ data(3963) clinic(1234) research(1004) }
{ studi(1410) differ(1259) use(1210) }
{ risk(3053) factor(974) diseas(938) }
{ perform(999) metric(946) measur(919) }
{ import(1318) role(1303) understand(862) }
{ model(2341) predict(2261) use(1141) }
{ visual(1396) interact(850) tool(830) }
{ compound(1573) activ(1297) structur(1058) }
{ studi(1119) effect(1106) posit(819) }
{ blood(1257) pressur(1144) flow(957) }
{ spatial(1525) area(1432) region(1030) }
{ record(1888) medic(1808) patient(1693) }
{ health(3367) inform(1360) care(1135) }
{ model(3480) simul(1196) paramet(876) }
{ monitor(1329) mobil(1314) devic(1160) }
{ ehr(2073) health(1662) electron(1139) }
{ research(1218) medic(880) student(794) }
{ patient(2837) hospit(1953) medic(668) }
{ model(2656) set(1616) predict(1553) }
{ age(1611) year(1155) adult(843) }
{ medic(1828) order(1363) alert(1069) }
{ signal(2180) analysi(812) frequenc(800) }
{ gene(2352) biolog(1181) express(1162) }
{ data(3008) multipl(1320) sourc(1022) }
{ first(2504) two(1366) second(1323) }
{ intervent(3218) particip(2042) group(1664) }
{ activ(1138) subject(705) human(624) }
{ time(1939) patient(1703) rate(768) }
{ patient(1821) servic(1111) care(1106) }
{ health(1844) social(1437) communiti(874) }
{ structur(1116) can(940) graph(676) }
{ high(1669) rate(1365) level(1280) }
{ use(976) code(926) identifi(902) }
{ drug(1928) target(777) effect(648) }
{ result(1111) use(1088) new(759) }
{ implement(1333) system(1263) develop(1122) }
{ activ(1452) weight(1219) physic(1104) }

Resumo

Nowadays, a wide range of serum tumor markers can be applied in the diagnosis of colorectal cancer. There exists a wide variability in the type and number of routinely used markers so that, sometimes, patients may receive redundant or insufficient checks. Furthermore, the traditional single cutoff point also hinders the efficient utilization of the continuous check value of a tumor marker. In order to improve the diagnostic accuracy (DA) and decrease the cost, it is necessary to optimize the check combinations and exploit the check values fully. To this end, focusing on colorectal cancer (CRC), an artificial intelligent algorithm entitled DS-STM (diagnosis strategy of serum tumor makers) is developed in this paper. DS-STM can provide decision support for physicians on the usage of different tumor markers and diagnosis of colorectal cancer (CRC). The study demonstrates that, instead of five or more tumor markers, two markers are already enough for diagnosis for most CRC patients. The experimental study shows, compared to the traditional serial test, DS-STM can improve DA from 67.53% to 73.87% for the same validation dataset. In addition, a significant cost reduction can be achieved with the new developed diagnosis strategy.

Resumo Limpo

nowaday wide rang serum tumor marker can appli diagnosi colorect cancer exist wide variabl type number routin use marker sometim patient may receiv redund insuffici check furthermor tradit singl cutoff point also hinder effici util continu check valu tumor marker order improv diagnost accuraci da decreas cost necessari optim check combin exploit check valu fulli end focus colorect cancer crc artifici intellig algorithm entitl dsstm diagnosi strategi serum tumor maker develop paper dsstm can provid decis support physician usag differ tumor marker diagnosi colorect cancer crc studi demonstr instead five tumor marker two marker alreadi enough diagnosi crc patient experiment studi show compar tradit serial test dsstm can improv da valid dataset addit signific cost reduct can achiev new develop diagnosi strategi

Resumos Similares

AMIA Annu Symp Proc - Logical Differential Prediction Bayes Net, improving breast cancer diagnosis for older women. ( 0,750478665472655 )
Comput Methods Programs Biomed - Ultrasound based application for intraglandular mapping of breast cancer. ( 0,74505657975046 )
J Digit Imaging - Presentation of similar images as a reference for distinction between benign and malignant masses on mammograms: analysis of initial observer study. ( 0,738197002474473 )
Med Biol Eng Comput - Measurement of bioelectric and acoustic profile of breast tissue using hybrid magnetoacoustic method for cancer detection. ( 0,73177127759799 )
J Med Syst - The effect of artificial neural network model combined with six tumor markers in auxiliary diagnosis of lung cancer. ( 0,726192519792547 )
Comput Math Methods Med - Screening for cervical cancer using automated analysis of PAP-smears. ( 0,724746527310659 )
Comput Methods Programs Biomed - Automated estimation of disease recurrence in head and neck cancer using routine healthcare data. ( 0,718008080536125 )
J Med Syst - Thermography based breast cancer detection using texture features and Support Vector Machine. ( 0,716672302902645 )
Int J Comput Assist Radiol Surg - Breast masses detection using phase portrait analysis and fuzzy inference systems. ( 0,709234472264132 )
Comput Math Methods Med - Computer implementation of a new therapeutic model for GBM tumor. ( 0,707958614745851 )
Comput Methods Programs Biomed - A coarse-to-fine approach for segmenting melanocytic skin lesions in standard camera images. ( 0,707036358069316 )
Comput. Biol. Med. - Segmentation of histopathology HER2/neu images with fuzzy decision tree and Takagi-Sugeno reasoning. ( 0,705383969546502 )
Comput Math Methods Med - Computer aided detection of breast density and mass, and visualization of other breast anatomical regions on mammograms using graph cuts. ( 0,701138786852866 )
J Med Syst - Construction the model on the breast cancer survival analysis use support vector machine, logistic regression and decision tree. ( 0,696351488664028 )
J Med Syst - Breast alert: an on-line tool for predicting the lifetime risk of women breast cancer. ( 0,693942979850558 )
Comput Methods Programs Biomed - Critical laboratory result reporting system in cancer patients. ( 0,691180368290711 )
Lifetime Data Anal - Group sequential tests for long-term survival comparisons. ( 0,686761228196137 )
Comput Methods Programs Biomed - The classification of cancer stage microarray data. ( 0,68304671381702 )
AMIA Annu Symp Proc - Alignment and clustering of breast cancer patients by longitudinal treatment history. ( 0,672138520391236 )
Med Biol Eng Comput - Biomedical application of fuzzy association rules for identifying breast cancer biomarkers. ( 0,669464827366019 )
BMC Med Inform Decis Mak - An improved survivability prognosis of breast cancer by using sampling and feature selection technique to solve imbalanced patient classification data. ( 0,669063876753097 )
Comput Math Methods Med - Evaluation of the diagnostic power of thermography in breast cancer using Bayesian network classifiers. ( 0,668923883937894 )
Med Decis Making - Decision Regret following Treatment for Localized Breast Cancer: Is Regret Stable Over Time? ( 0,668246745691649 )
Comput Methods Programs Biomed - Breast density classification to reduce false positives in CADe systems. ( 0,665602639908882 )
J Med Syst - Application of intelligent systems in asthma disease: designing a fuzzy rule-based system for evaluating level of asthma exacerbation. ( 0,656901102474975 )
J Med Syst - An expert support system for breast cancer diagnosis using color wavelet features. ( 0,655332595467775 )
Comput Math Methods Med - Risk-adaptive volumetric modulated arc therapy using biological objective functions for subvolume boosting in radiotherapy. ( 0,654264574881207 )
Comput Math Methods Med - Modeling the spatial distribution of chronic tumor hypoxia: implications for experimental and clinical studies. ( 0,653068934249679 )
J. Med. Internet Res. - Do cancer patients tweet? Examining the twitter use of cancer patients in Japan. ( 0,650701063993367 )
Comput Math Methods Med - Optimal treatment strategy for a tumor model under immune suppression. ( 0,64993660162886 )
Comput Math Methods Med - Assessing the effects of estrogen on the dynamics of breast cancer. ( 0,649309640015031 )
Int J Comput Assist Radiol Surg - Value of CT, FDG PET-CT and serum tumor markers in staging recurrent colorectal cancer. ( 0,64717622714929 )
BMC Med Inform Decis Mak - Factors influencing the surgery intentions and choices of women with early breast cancer: the predictive utility of an extended theory of planned behaviour. ( 0,644658371220304 )
J Med Syst - Classification of benign and malignant breast masses based on shape and texture features in sonography images. ( 0,642154411316529 )
Med Decis Making - Patients' preferences and priorities regarding colorectal cancer screening. ( 0,639341273294149 )
Comput Math Methods Med - An estrogen model: the relationship between body mass index, menopausal status, estrogen replacement therapy, and breast cancer risk. ( 0,63754310925934 )
J Med Syst - An improved decision support system for detection of lesions in mammograms using Differential Evolution Optimized Wavelet Neural Network. ( 0,636543574540971 )
J Med Syst - A hybrid automatic system for the diagnosis of lung cancer based on genetic algorithm and fuzzy extreme learning machines. ( 0,626089552696835 )
Comput Math Methods Med - Artificial neural networks in mammography interpretation and diagnostic decision making. ( 0,624894353655878 )
BMC Med Inform Decis Mak - Essential pre-treatment imaging examinations in patients with endoscopically-diagnosed early gastric cancer. ( 0,624142888088466 )
AMIA Annu Symp Proc - Integrating machine learning and physician knowledge to improve the accuracy of breast biopsy. ( 0,623309952488946 )
J Am Med Inform Assoc - Automatic glaucoma diagnosis through medical imaging informatics. ( 0,621872387833437 )
Wiley Interdiscip Rev Syst Biol Med - Intercellular adhesion: mechanisms for growth and metastasis of epithelial cancers. ( 0,620722428707674 )
Comput Methods Programs Biomed - Pectoral muscle segmentation: a review. ( 0,619969154262855 )
J Am Med Inform Assoc - Automatic classification of mammography reports by BI-RADS breast tissue composition class. ( 0,619151990691404 )
Comput. Biol. Med. - Thermal analysis of a three-dimensional breast model with embedded tumour using the transmission line matrix (TLM) method. ( 0,615232634608784 )
BMC Med Inform Decis Mak - Public stated preferences and predicted uptake for genome-based colorectal cancer screening. ( 0,613279336211676 )
Int J Health Geogr - Estrogen receptor positive breast cancers and their association with environmental factors. ( 0,608993428150265 )
Med Decis Making - Comparison of surveillance strategies for low-risk bladder cancer patients. ( 0,608643762060506 )
Comput Methods Programs Biomed - Mammogram retrieval on similar mass lesions. ( 0,608301837341048 )
Med Biol Eng Comput - In vitro electroretinogram for the study of the functionality of differentiated retinal pigment epithelium cells. ( 0,607578035744147 )
Med Decis Making - Deceiving numbers: survival rates and their impact on doctors' risk communication. ( 0,606973716262449 )
J Am Med Inform Assoc - Validating drug repurposing signals using electronic health records: a case study of metformin associated with reduced cancer mortality. ( 0,604789193832623 )
Comput. Biol. Med. - Risk classification of cancer survival using ANN with gene expression data from multiple laboratories. ( 0,60402086888335 )
Comput. Biol. Med. - Computer simulations on multiprobe freezing of irregularly shaped tumors. ( 0,602039766433406 )
Wiley Interdiscip Rev Syst Biol Med - Gut stem cells in tissue renewal and disease: methods, markers, and myths. ( 0,601868559729547 )
J Med Syst - Breast cancer classification based on advanced multi dimensional fuzzy neural network. ( 0,599657199948204 )
BMC Med Inform Decis Mak - Accuracy validation of adjuvant! online in Taiwanese breast cancer patients--a 10-year analysis. ( 0,598235329028673 )
J Med Syst - Mammographic image based breast tissue classification with kernel self-optimized fisher discriminant for breast cancer diagnosis. ( 0,597747250875508 )
Int J Health Geogr - Correlation of the ratio of metastatic to non-metastatic cancer cases with the degree of socioeconomic deprivation among Texas counties. ( 0,595562327420084 )
Med Biol Eng Comput - Automated mechanical ventilation: adapting decision making to different disease states. ( 0,595382763631345 )
Comput Methods Programs Biomed - Breast mass contour segmentation algorithm in digital mammograms. ( 0,594335543888795 )
J Med Syst - Support vector machine based diagnostic system for breast cancer using swarm intelligence. ( 0,593863833779057 )
Comput Math Methods Med - Modeling of non-small cell lung cancer volume changes during CT-based image guided radiotherapy: patterns observed and clinical implications. ( 0,591713074590601 )
J Med Syst - Prediction of breast cancer using artificial neural networks. ( 0,58799871836707 )
Comput. Biol. Med. - A DIAMOND method of inducing classification rules for biological data. ( 0,585857226224952 )
Med Decis Making - The Understanding of Terminal Cancer and Its Relationship with Attitudes toward End-of-Life Care Issues. ( 0,585757016550583 )
Comput. Biol. Med. - Automatic segmentation of lung nodules with growing neural gas and support vector machine. ( 0,58375501584217 )
J Clin Monit Comput - Potential of surface acoustic wave biosensors for early sepsis diagnosis. ( 0,583570392994379 )
Med Decis Making - Optimization of PSA screening policies: a comparison of the patient and societal perspectives. ( 0,582798279993592 )
Comput. Biol. Med. - Modeling and predicting the occurrence of brain metastasis from lung cancer by Bayesian network: a case study of Taiwan. ( 0,582448383750805 )
J Biomed Inform - Mutual information-based template matching scheme for detection of breast masses: from mammography to digital breast tomosynthesis. ( 0,582283267267331 )
J Med Syst - A swarm optimized neural network system for classification of microcalcification in mammograms. ( 0,581712460753337 )
Inform Health Soc Care - Spontaneously published illness stories on a website for young women with breast cancer: do writers and themes reflect the wider population? ( 0,581508318136369 )
J Med Syst - Microwave tomography analysis system for breast tumor detection. ( 0,581015021922754 )
Comput Methods Programs Biomed - Computer aided detection system for micro calcifications in digital mammograms. ( 0,580574027522263 )
Comput Math Methods Med - The value of private patient information in the physician-patient relationship: a game-theoretic account. ( 0,57888129545644 )
J Med Syst - Breast tissue image classification based on Semi-supervised Locality Discriminant Projection with Kernels. ( 0,576774082707548 )
J Med Syst - A new hybrid case-based reasoning approach for medical diagnosis systems. ( 0,576670733917217 )
J. Med. Internet Res. - An online resource of digital stories about cancer genetics: qualitative study of patient preferences and information needs. ( 0,574728291415897 )
Artif Intell Med - Characterization of spatiotemporal changes for the classification of dynamic contrast-enhanced magnetic-resonance breast lesions. ( 0,574326444185182 )
Med Decis Making - A review and meta-analysis of utility values for lung cancer. ( 0,571398606943214 )
Int J Med Robot - Robotic surgery for staging of serous papillary and clear cell carcinoma of the endometrium. ( 0,571372457528638 )
J Med Syst - Evaluation of the efficiency of biofield diagnostic system in breast cancer detection using clinical study results and classifiers. ( 0,570232247509671 )
Comput Math Methods Med - Breast cancer characterization based on image classification of tissue sections visualized under low magnification. ( 0,56499776286873 )
Comput Methods Programs Biomed - A new algorithm for automatic vascular mapping of DCE-MRI of the breast: Clinical application of a potential new biomarker. ( 0,563576091341518 )
Comput Math Methods Med - Development of an expert system as a diagnostic support of cervical cancer in atypical glandular cells, based on fuzzy logics and image interpretation. ( 0,562921784414032 )
J Am Med Inform Assoc - Applying operations research to optimize a novel population management system for cancer screening. ( 0,56072617665111 )
Med Decis Making - How does early detection by screening affect disease progression? Modeling estimated benefits in prostate cancer screening. ( 0,560307480120284 )
J Med Syst - Automated detection of breast cancer in thermal infrared images, based on independent component analysis. ( 0,560208621920621 )
Comput. Biol. Med. - A non-linear morphometric feature selection approach for breast tumor contour from ultrasonic images. ( 0,559445359386735 )
AMIA Annu Symp Proc - Analysis of Breast Contour using Rotated Catenary. ( 0,558216895761044 )
J Am Med Inform Assoc - An interactive Bayesian model for prediction of lymph node ratio and survival in pancreatic cancer patients. ( 0,557581614641231 )
Comput Methods Programs Biomed - A novel automatic suspicious mass regions identification using Havrda & Charvat entropy and Otsu's N thresholding. ( 0,557387457234614 )
Comput Methods Programs Biomed - A hybrid fuzzy-ontology based intelligent system to determine level of severity and treatment recommendation for Benign Prostatic Hyperplasia. ( 0,556244930277924 )
Int J Med Inform - Evaluation of different features of an eHealth application for personalized illness management support: cancer patients' use and appraisal of usefulness. ( 0,555563806465248 )
Comput Math Methods Med - Using the K-nearest neighbor algorithm for the classification of lymph node metastasis in gastric cancer. ( 0,555425132198684 )
BMC Med Inform Decis Mak - Testing a Spanish-language colorectal cancer screening decision aid in Latinos with limited English proficiency: results from a pre-post trial and four month follow-up survey. ( 0,55468786593262 )
Comput. Biol. Med. - A novel approach for detection and classification of mammographic microcalcifications using wavelet analysis and extreme learning machine. ( 0,55369945966579 )
Comput. Biol. Med. - Computer-aided diagnosis of breast cancer based on fine needle biopsy microscopic images. ( 0,5528541013468 )