Comput Methods Programs Biomed - A method for corneal nerves automatic segmentation and morphometric analysis.

Tópicos

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{ detect(2391) sensit(1101) algorithm(908) }
{ patient(2315) diseas(1263) diabet(1191) }
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Resumo

The segmentation and morphometric analysis of corneal sub-basal nerves, from corneal confocal microscopy images, has gained recently an increased interest. This interest arises from the possibility of using changes in these nerves as the basis of a simple and non-invasive method for early detection and follow-up of peripheral diabetic neuropathy, a major cause of chronic disability in diabetic patients. Here, we propose one method for automatic segmentation and analysis of corneal nerves from images obtained in vivo through corneal confocal microscopy. The method is capable of segmenting corneal nerves, with sensitivity near 90% and a percentage of false recognitions with an average of 5.3%. The nerves tortuosity was calculated and shows statistically significant differences between healthy controls and diabetic individuals, in accordance to what is reported in the literature.

Resumo Limpo

segment morphometr analysi corneal subbas nerv corneal confoc microscopi imag gain recent increas interest interest aris possibl use chang nerv basi simpl noninvas method earli detect followup peripher diabet neuropathi major caus chronic disabl diabet patient propos one method automat segment analysi corneal nerv imag obtain vivo corneal confoc microscopi method capabl segment corneal nerv sensit near percentag fals recognit averag nerv tortuos calcul show statist signific differ healthi control diabet individu accord report literatur

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