Comput. Biol. Med. - Strain measurement from 3D micro-CT images of a breast-mimicking phantom.

Tópicos

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Resumo

Strain distribution in compressed tissues gives information about elasticity of the tissues. We have measured strain from two sets of 3D micro-CT images of a breast-mimicking phantom; one obtained without compressing the phantom and the other with compressing it. To measure strain, we first calculated compression-induced displacements of high-intensity feature patterns in the image. In measuring displacement of a pixel of interest, we searched the pixel in the compressed-phantom image, whose surrounding resembles the uncompressed-phantom image most closely, using the image correlation technique. From the displacement data, we calculated average strain at a region of interest. With the calculated average strains, we could distinguish the hard inclusion in the phantom which was not distinguishable from the background body of the phantom in the ordinary micro-CT images. The calculated strains account for stiffness of the tissue of interest, one of the important parameters for diagnosing malignant tissues. We present experimental results of the displacement and strain measurement along with FEM analysis results.

Resumo Limpo

strain distribut compress tissu give inform elast tissu measur strain two set d microct imag breastmimick phantom one obtain without compress phantom compress measur strain first calcul compressioninduc displac highintens featur pattern imag measur displac pixel interest search pixel compressedphantom imag whose surround resembl uncompressedphantom imag close use imag correl techniqu displac data calcul averag strain region interest calcul averag strain distinguish hard inclus phantom distinguish background bodi phantom ordinari microct imag calcul strain account stiff tissu interest one import paramet diagnos malign tissu present experiment result displac strain measur along fem analysi result

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