Comput. Biol. Med. - Segmentation of anterior cruciate ligament in knee MR images using graph cuts with patient-specific shape constraints and label refinement.

Tópicos

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Resumo

We propose a graph-cut-based segmentation method for the anterior cruciate ligament (ACL) in knee MRI with a novel shape prior and label refinement. As the initial seeds for graph cuts, candidates for the ACL and the background are extracted from knee MRI roughly by means of adaptive thresholding with Gaussian mixture model fitting. The extracted ACL candidate is segmented iteratively by graph cuts with patient-specific shape constraints. Two shape constraints termed fence and neighbor costs are suggested such that the graph cuts prevent any leakage into adjacent regions with similar intensity. The segmented ACL label is refined by means of superpixel classification. Superpixel classification makes the segmented label propagate into missing inhomogeneous regions inside the ACL. In the experiments, the proposed method segmented the ACL with Dice similarity coefficient of 66.47?7.97%, average surface distance of 2.247?0.869, and root mean squared error of 3.538?1.633, which increased the accuracy by 14.8%, 40.3%, and 37.6% from the Boykov model, respectively.

Resumo Limpo

propos graphcutbas segment method anterior cruciat ligament acl knee mri novel shape prior label refin initi seed graph cut candid acl background extract knee mri rough mean adapt threshold gaussian mixtur model fit extract acl candid segment iter graph cut patientspecif shape constraint two shape constraint term fenc neighbor cost suggest graph cut prevent leakag adjac region similar intens segment acl label refin mean superpixel classif superpixel classif make segment label propag miss inhomogen region insid acl experi propos method segment acl dice similar coeffici averag surfac distanc root mean squar error increas accuraci boykov model respect

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