Comput. Biol. Med. - Effect of bunching of cilia and their interplay on muco-ciliary transport.

Tópicos

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{ detect(2391) sensit(1101) algorithm(908) }

Resumo

Cilia are hair-like organelles projecting from a eukaryotic cell, used either for locomotion or as sensors. Cilia commonly occur in patches. To take this into consideration, we represent cilia in multiple patches, instead of the conventional 'dense mat' representation. We focus on the combined action and interplay of these patches. The effects of varying the frequency, spacing and phase lag of the beating of one cilia bunch with respect to the beating of adjacent patches are studied. We model the Airway Surface Liquid (ASL) as a three-layer structure. The possibility of an optimum frequency of beating is noted and the change of mucous flow under different spacing and phase differences are observed.

Resumo Limpo

cilia hairlik organell project eukaryot cell use either locomot sensor cilia common occur patch take consider repres cilia multipl patch instead convent dens mat represent focus combin action interplay patch effect vari frequenc space phase lag beat one cilia bunch respect beat adjac patch studi model airway surfac liquid asl threelay structur possibl optimum frequenc beat note chang mucous flow differ space phase differ observ

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