Comput. Biol. Med. - Automated identification of normal and diabetes heart rate signals using nonlinear measures.

Tópicos

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Resumo

Diabetes mellitus (DM) affects considerable number of people in the world and the number of cases is increasing every year. Due to a strong link to the genetic basis of the disease, it is extremely difficult to cure. However, it can be controlled to prevent severe consequences, such as organ damage. Therefore, diabetes diagnosis and monitoring of its treatment is very important. In this paper, we have proposed a non-invasive diagnosis support system for DM. The system determines whether or not diabetes is present by determining the cardiac health of a patient using heart rate variability (HRV) analysis. This analysis was based on nine nonlinear features namely: Approximate Entropy (ApEn), largest Lyapunov exponet (LLE), detrended fluctuation analysis (DFA) and recurrence quantification analysis (RQA). Clinically significant measures were used as input to classification algorithms, namely AdaBoost, decision tree (DT), fuzzy Sugeno classifier (FSC), k-nearest neighbor algorithm (k-NN), probabilistic neural network (PNN) and support vector machine (SVM). Ten-fold stratified cross-validation was used to select the best classifier. AdaBoost, with least squares (LS) as weak learner, performed better than the other classifiers, yielding an average accuracy of 90%, sensitivity of 92.5% and specificity of 88.7%.

Resumo Limpo

diabet mellitus dm affect consider number peopl world number case increas everi year due strong link genet basi diseas extrem difficult cure howev can control prevent sever consequ organ damag therefor diabet diagnosi monitor treatment import paper propos noninvas diagnosi support system dm system determin whether diabet present determin cardiac health patient use heart rate variabl hrv analysi analysi base nine nonlinear featur name approxim entropi apen largest lyapunov exponet lle detrend fluctuat analysi dfa recurr quantif analysi rqa clinic signific measur use input classif algorithm name adaboost decis tree dt fuzzi sugeno classifi fsc knearest neighbor algorithm knn probabilist neural network pnn support vector machin svm tenfold stratifi crossvalid use select best classifi adaboost least squar ls weak learner perform better classifi yield averag accuraci sensit specif

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