Comput. Biol. Med. - Sparse Manifold Clustering and Embedding to discriminate gene expression profiles of glioblastoma and meningioma tumors.

Tópicos

{ learn(2355) train(1041) set(1003) }
{ perform(1367) use(1326) method(1137) }
{ method(1969) cluster(1462) data(1082) }
{ gene(2352) biolog(1181) express(1162) }
{ featur(3375) classif(2383) classifi(1994) }
{ imag(1947) propos(1133) code(1026) }
{ model(3480) simul(1196) paramet(876) }
{ drug(1928) target(777) effect(648) }
{ imag(2675) segment(2577) method(1081) }
{ motion(1329) object(1292) video(1091) }
{ error(1145) method(1030) estim(1020) }
{ chang(1828) time(1643) increas(1301) }
{ cancer(2502) breast(956) screen(824) }
{ estim(2440) model(1874) function(577) }
{ sequenc(1873) structur(1644) protein(1328) }
{ method(1219) similar(1157) match(930) }
{ network(2748) neural(1063) input(814) }
{ treatment(1704) effect(941) patient(846) }
{ problem(2511) optim(1539) algorithm(950) }
{ clinic(1479) use(1117) guidelin(835) }
{ method(1557) propos(1049) approach(1037) }
{ featur(1941) imag(1645) propos(1176) }
{ howev(809) still(633) remain(590) }
{ record(1888) medic(1808) patient(1693) }
{ model(2656) set(1616) predict(1553) }
{ cost(1906) reduc(1198) effect(832) }
{ data(3008) multipl(1320) sourc(1022) }
{ high(1669) rate(1365) level(1280) }
{ use(976) code(926) identifi(902) }
{ result(1111) use(1088) new(759) }
{ method(2212) result(1239) propos(1039) }
{ model(3404) distribut(989) bayesian(671) }
{ can(774) often(719) complex(702) }
{ data(1737) use(1416) pattern(1282) }
{ inform(2794) health(2639) internet(1427) }
{ system(1976) rule(880) can(841) }
{ measur(2081) correl(1212) valu(896) }
{ imag(1057) registr(996) error(939) }
{ bind(1733) structur(1185) ligand(1036) }
{ imag(2830) propos(1344) filter(1198) }
{ patient(2315) diseas(1263) diabet(1191) }
{ take(945) account(800) differ(722) }
{ studi(2440) review(1878) systemat(933) }
{ assess(1506) score(1403) qualiti(1306) }
{ surgeri(1148) surgic(1085) robot(1054) }
{ framework(1458) process(801) describ(734) }
{ concept(1167) ontolog(924) domain(897) }
{ algorithm(1844) comput(1787) effici(935) }
{ extract(1171) text(1153) clinic(932) }
{ data(1714) softwar(1251) tool(1186) }
{ design(1359) user(1324) use(1319) }
{ control(1307) perform(991) simul(935) }
{ model(2220) cell(1177) simul(1124) }
{ care(1570) inform(1187) nurs(1089) }
{ general(901) number(790) one(736) }
{ method(984) reconstruct(947) comput(926) }
{ search(2224) databas(1162) retriev(909) }
{ case(1353) use(1143) diagnosi(1136) }
{ data(3963) clinic(1234) research(1004) }
{ studi(1410) differ(1259) use(1210) }
{ risk(3053) factor(974) diseas(938) }
{ perform(999) metric(946) measur(919) }
{ research(1085) discuss(1038) issu(1018) }
{ system(1050) medic(1026) inform(1018) }
{ import(1318) role(1303) understand(862) }
{ model(2341) predict(2261) use(1141) }
{ visual(1396) interact(850) tool(830) }
{ compound(1573) activ(1297) structur(1058) }
{ studi(1119) effect(1106) posit(819) }
{ blood(1257) pressur(1144) flow(957) }
{ spatial(1525) area(1432) region(1030) }
{ health(3367) inform(1360) care(1135) }
{ monitor(1329) mobil(1314) devic(1160) }
{ ehr(2073) health(1662) electron(1139) }
{ state(1844) use(1261) util(961) }
{ research(1218) medic(880) student(794) }
{ patient(2837) hospit(1953) medic(668) }
{ data(2317) use(1299) case(1017) }
{ age(1611) year(1155) adult(843) }
{ medic(1828) order(1363) alert(1069) }
{ signal(2180) analysi(812) frequenc(800) }
{ group(2977) signific(1463) compar(1072) }
{ sampl(1606) size(1419) use(1276) }
{ first(2504) two(1366) second(1323) }
{ intervent(3218) particip(2042) group(1664) }
{ activ(1138) subject(705) human(624) }
{ time(1939) patient(1703) rate(768) }
{ patient(1821) servic(1111) care(1106) }
{ use(2086) technolog(871) perceiv(783) }
{ can(981) present(881) function(850) }
{ analysi(2126) use(1163) compon(1037) }
{ health(1844) social(1437) communiti(874) }
{ structur(1116) can(940) graph(676) }
{ use(1733) differ(960) four(931) }
{ implement(1333) system(1263) develop(1122) }
{ survey(1388) particip(1329) question(1065) }
{ decis(3086) make(1611) patient(1517) }
{ process(1125) use(805) approach(778) }
{ activ(1452) weight(1219) physic(1104) }
{ detect(2391) sensit(1101) algorithm(908) }

Resumo

Sparse Manifold Clustering and Embedding (SMCE) algorithm has been recently proposed for simultaneous clustering and dimensionality reduction of data on nonlinear manifolds using sparse representation techniques. In this work, SMCE algorithm is applied to the differential discrimination of Glioblastoma and Meningioma Tumors by means of their Gene Expression Profiles. Our purpose was to evaluate the robustness of this nonlinear manifold to classify gene expression profiles, characterized by the high-dimensionality of their representations and the low discrimination power of most of the genes. For this objective, we used SMCE to reduce the dimensionality of a preprocessed dataset of 35 single-labeling cDNA microarrays with 11500 original clones. Afterwards, supervised and unsupervised methodologies were applied to obtain the classification model: the former was based on linear discriminant analysis, the later on clustering using the SMCE embedding data. The results obtained using both approaches showed that all (100%) the samples could be correctly classified and the results of all repetitions but one formed a compatible cluster of predictive labels. Finally, the embedding dimensionality of the dataset extracted by SMCE revealed large discrimination margins between both classes.

Resumo Limpo

spars manifold cluster embed smce algorithm recent propos simultan cluster dimension reduct data nonlinear manifold use spars represent techniqu work smce algorithm appli differenti discrimin glioblastoma meningioma tumor mean gene express profil purpos evalu robust nonlinear manifold classifi gene express profil character highdimension represent low discrimin power gene object use smce reduc dimension preprocess dataset singlelabel cdna microarray origin clone afterward supervis unsupervis methodolog appli obtain classif model former base linear discrimin analysi later cluster use smce embed data result obtain use approach show sampl correct classifi result repetit one form compat cluster predict label final embed dimension dataset extract smce reveal larg discrimin margin class

Resumos Similares

Comput Math Methods Med - On multilabel classification methods of incompletely labeled biomedical text data. ( 0,843089852231713 )
IEEE Trans Image Process - Joint segmentation of images and scanned point cloud in large-scale street scenes with low-annotation cost. ( 0,820782781997477 )
Comput Math Methods Med - Correlation kernels for support vector machines classification with applications in cancer data. ( 0,811686616457539 )
Neural Comput - Reduction from cost-sensitive ordinal ranking to weighted binary classification. ( 0,808321626772774 )
Neural Comput - Computing sparse representations of multidimensional signals using Kronecker bases. ( 0,79134430967836 )
J Biomed Inform - Semi-supervised clinical text classification with Laplacian SVMs: an application to cancer case management. ( 0,788906433114359 )
Int J Neural Syst - Aggregation of sparse linear discriminant analyses for event-related potential classification in brain-computer interface. ( 0,78701818149236 )
Artif Intell Med - A classifier ensemble approach for the missing feature problem. ( 0,786068782809195 )
J Med Syst - 3D similarity-dissimilarity plot for high dimensional data visualization in the context of biomedical pattern classification. ( 0,784171936228241 )
IEEE Trans Image Process - Task-specific image partitioning. ( 0,782842531426851 )
IEEE Trans Image Process - Geodesic propagation for semantic labeling. ( 0,781521652618284 )
IEEE Trans Pattern Anal Mach Intell - Distance-Based Image Classification: Generalizing to New Classes at Near Zero Cost. ( 0,780490635003893 )
J. Comput. Biol. - Imbalanced class learning in epigenetics. ( 0,775115692146073 )
IEEE Trans Image Process - Improving Web image search by bag-based reranking. ( 0,772901206417269 )
J Am Med Inform Assoc - Learning classification models with soft-label information. ( 0,772737958534032 )
IEEE Trans Neural Netw Learn Syst - Adaptive Batch Mode Active Learning. ( 0,767404381258731 )
IEEE Trans Image Process - Manifold regularized multitask learning for semi-supervised multilabel image classification. ( 0,762004804520564 )
Neural Comput - Adaptive metric learning vector quantization for ordinal classification. ( 0,756354756442263 )
Neural Comput - Divergence-based vector quantization. ( 0,752483875925456 )
IEEE Trans Image Process - A linear support higher-order tensor machine for classification. ( 0,751545828571869 )
IEEE Trans Image Process - Multiview Hessian regularization for image annotation. ( 0,749719998025315 )
IEEE Trans Pattern Anal Mach Intell - Label Consistent K-SVD: Learning A Discriminative Dictionary for Recognition. ( 0,749085275985641 )
IEEE Trans Image Process - Learning discriminative dictionary for group sparse representation. ( 0,745938442906404 )
IEEE Trans Pattern Anal Mach Intell - Feature Selection with Conjunctions of Decision Stumps and Learning from Microarray Data. ( 0,745787745921144 )
Neural Comput - Large margin low rank tensor analysis. ( 0,744924172960181 )
IEEE Trans Neural Netw Learn Syst - ML-Tree: a tree-structure-based approach to multilabel learning. ( 0,737388774761158 )
Comput Methods Programs Biomed - Multistage approach for clustering and classification of ECG data. ( 0,737322430954016 )
Comput. Biol. Med. - Robust prediction of protein subcellular localization combining PCA and WSVMs. ( 0,734682602798856 )
J. Comput. Biol. - Locally learning biomedical data using diffusion frames. ( 0,734215182190372 )
J Biomed Inform - Learning classification models from multiple experts. ( 0,73401666407573 )
IEEE Trans Image Process - Multiple-kernel, multiple-instance similarity features for efficient visual object detection. ( 0,733423289761403 )
Artif Intell Med - A fuzzy-based data transformation for feature extraction to increase classification performance with small medical data sets. ( 0,731765298137006 )
Comput Methods Programs Biomed - An attribute weight assignment and particle swarm optimization algorithm for medical database classifications. ( 0,728833200686989 )
Neural Comput - Online learning with (multiple) kernels: a review. ( 0,725529435568835 )
IEEE Trans Neural Netw Learn Syst - A Kernel Classification Framework for Metric Learning. ( 0,725286719035253 )
Int J Neural Syst - Structurally enhanced incremental neural learning for image classification with subgraph extraction. ( 0,723459609228598 )
IEEE Trans Image Process - Structured max-margin learning for inter-related classifier training and multilabel image annotation. ( 0,722530742521524 )
IEEE J Biomed Health Inform - Systematic Poisoning Attacks on and Defenses for Machine Learning in Healthcare. ( 0,721895863427393 )
IEEE Trans Image Process - Active learning for solving the incomplete data problem in facial age classification by the furthest nearest-neighbor criterion. ( 0,721566486785344 )
J Chem Inf Model - Classifying large chemical data sets: using a regularized potential function method. ( 0,720712266469133 )
Int J Neural Syst - Online semi-supervised growing neural gas. ( 0,717701449053216 )
IEEE Trans Pattern Anal Mach Intell - Feature Selection and Kernel Learning for Local Learning-Based Clustering. ( 0,71702681233781 )
Neural Comput - Metacognitive learning in a fully complex-valued radial basis function neural network. ( 0,71664776926073 )
J Am Med Inform Assoc - Supervised machine learning and active learning in classification of radiology reports. ( 0,716002577535189 )
J Biomed Inform - Applying active learning to assertion classification of concepts in clinical text. ( 0,715612634511042 )
J Am Med Inform Assoc - Missing values in deduplication of electronic patient data. ( 0,712712973190001 )
Int J Neural Syst - Span: spike pattern association neuron for learning spatio-temporal spike patterns. ( 0,711675934608736 )
IEEE Trans Image Process - Unsupervised amplitude and texture classification of SAR images with multinomial latent model. ( 0,711209874210365 )
J Biomed Inform - Portable automatic text classification for adverse drug reaction detection via multi-corpus training. ( 0,708594045656965 )
Comput Methods Programs Biomed - Comparison of machine learning methods for classifying aphasic and non-aphasic speakers. ( 0,708401612487422 )
J Biomed Inform - Class proximity measures--dissimilarity-based classification and display of high-dimensional data. ( 0,707857543403718 )
Int J Neural Syst - Linear time relational prototype based learning. ( 0,703880198800034 )
IEEE Trans Image Process - Hyperspectral image classification through bilayer graph-based learning. ( 0,699744294976212 )
Neural Comput - Feature selection for ordinal text classification. ( 0,69662866844544 )
J Biomed Inform - Incremental Gaussian Discriminant Analysis based on Graybill and Deal weighted combination of estimators for brain tumour diagnosis. ( 0,693646536432053 )
IEEE Trans Image Process - Design of non-linear kernel dictionaries for object recognition. ( 0,693609161660376 )
IEEE Trans Image Process - Cross-Device Automated Prostate Cancer Localization With Multiparametric MRI. ( 0,692583012837616 )
Artif Intell Med - Screening nonrandomized studies for medical systematic reviews: a comparative study of classifiers. ( 0,690794335319998 )
IEEE Trans Image Process - Incremental training of a detector using online sparse eigendecomposition. ( 0,690300411474575 )
IEEE Trans Neural Netw Learn Syst - Learning Stable Multilevel Dictionaries for Sparse Representations. ( 0,690146049382454 )
J Chem Inf Model - Training based on ligand efficiency improves prediction of bioactivities of ligands and drug target proteins in a machine learning approach. ( 0,686320154359931 )
IEEE Trans Pattern Anal Mach Intell - The Effect of Model Misspecification on Semi-Supervised Classification. ( 0,684607363487533 )
J Biomed Inform - Multi-label classification of chronically ill patients with bag of words and supervised dimensionality reduction algorithms. ( 0,683243532807617 )
IEEE Trans Pattern Anal Mach Intell - Weakly Supervised Recognition of Daily Life Activities with Wearable Sensors. ( 0,68038706110509 )
IEEE Trans Image Process - Self-supervised online metric learning with low rank constraint for scene categorization. ( 0,680020971502849 )
Comput Methods Programs Biomed - Modified CC-LR algorithm with three diverse feature sets for motor imagery tasks classification in EEG based brain-computer interface. ( 0,678667495723372 )
IEEE Trans Image Process - Saliency and gist features for target detection in satellite images. ( 0,678483032105707 )
IEEE Trans Image Process - Enhancing training collections for image annotation: an instance-weighted mixture modeling approach. ( 0,678438916999458 )
Int J Comput Assist Radiol Surg - Statistical shape model of a liver for autopsy imaging. ( 0,677613392944996 )
IEEE Trans Pattern Anal Mach Intell - Learning Categories from Few Examples with Multi Model Knowledge Transfer. ( 0,677530083623206 )
BMC Med Inform Decis Mak - Learning to improve medical decision making from imbalanced data without a priori cost. ( 0,675535520353108 )
Neural Comput - Multiple spectral kernel learning and a gaussian complexity computation. ( 0,673011279128958 )
Neural Comput - Extended robust support vector machine based on financial risk minimization. ( 0,672649192264081 )
Neural Comput - Adaptive multiclass classification for brain computer interfaces. ( 0,669782670919617 )
IEEE Trans Pattern Anal Mach Intell - Good Practice in Large-Scale Learning for Image Classification. ( 0,66913825619382 )
Comput. Biol. Med. - Relabeling algorithm for retrieval of noisy instances and improving prediction quality. ( 0,665401147206944 )
Neural Comput - Unsupervised learning of generative and discriminative weights encoding elementary image components in a predictive coding model of cortical function. ( 0,664822264718779 )
J Med Syst - A new data preparation method based on clustering algorithms for diagnosis systems of heart and diabetes diseases. ( 0,663727636925152 )
J Chem Inf Model - Note on naive Bayes based on binary descriptors in cheminformatics. ( 0,66351803536663 )
Comput Methods Programs Biomed - Biomedical system based on the Discrete Hidden Markov Model using the Rocchio-Genetic approach for the classification of internal carotid artery Doppler signals. ( 0,660469085217653 )
J Biomed Inform - Learning Bayesian networks from survival data using weighting censored instances. ( 0,66027864140251 )
IEEE Trans Image Process - Data-dependent hashing based on p-stable distribution. ( 0,660056374176875 )
J Chem Inf Model - Atom environment kernels on molecules. ( 0,659846795897758 )
J Am Med Inform Assoc - Active learning for clinical text classification: is it better than random sampling? ( 0,65935556770217 )
IEEE Trans Pattern Anal Mach Intell - Facial Age Estimation by Learning from Label Distributions. ( 0,654846075766617 )
IEEE Trans Pattern Anal Mach Intell - Latent Dirichlet Allocation Models for Image Classification. ( 0,654843654658132 )
Artif Intell Med - Vicinal support vector classifier using supervised kernel-based clustering. ( 0,650848428047459 )
AMIA Annu Symp Proc - Comparison and combination of several MeSH indexing approaches. ( 0,650504987881977 )
IEEE Trans Neural Netw Learn Syst - Ordinal Distance Metric Learning for Image Ranking. ( 0,648583688943861 )
IEEE Trans Pattern Anal Mach Intell - A Bag-of-Features Framework to Classify Time Series. ( 0,645804896591039 )
Neural Comput - Representing objects, relations, and sequences. ( 0,645424384779378 )
IEEE Trans Neural Netw Learn Syst - Partially shared latent factor learning with multiview data. ( 0,642635843504106 )
IEEE Trans Image Process - Unified structured learning for simultaneous human pose estimation and garment attribute classification. ( 0,642018486954202 )
J Med Syst - 3D matrix pattern based Support Vector Machines for identifying pulmonary cancer in CT scanned images. ( 0,641080999940607 )
IEEE Trans Neural Netw Learn Syst - Evolutionary fuzzy ARTMAP neural networks for classification of semiconductor defects. ( 0,6393126862348 )
J Med Syst - Diagnosis of several diseases by using combined kernels with Support Vector Machine. ( 0,638788972529243 )
AMIA Annu Symp Proc - Sample-efficient learning with auxiliary class-label information. ( 0,638742148516175 )
IEEE Trans Neural Netw Learn Syst - An Experimentation Platform for On-Chip Integration of Analog Neural Networks: A Pathway to Trusted and Robust Analog/RF ICs. ( 0,63847164300004 )
IEEE Trans Neural Netw Learn Syst - An efficient topological distance-based tree kernel. ( 0,63798841063111 )
IEEE Trans Pattern Anal Mach Intell - Scene-Specific Pedestrian Detection for Static Video Surveillance. ( 0,637808894427626 )