Comput. Biol. Med. - Atherosclerotic indicators for blood-like fluids in 90-degree arterial-like bifurcations.


{ blood(1257) pressur(1144) flow(957) }
{ data(1737) use(1416) pattern(1282) }
{ studi(1119) effect(1106) posit(819) }
{ activ(1138) subject(705) human(624) }
{ can(774) often(719) complex(702) }
{ imag(2675) segment(2577) method(1081) }
{ model(2220) cell(1177) simul(1124) }
{ visual(1396) interact(850) tool(830) }
{ imag(2830) propos(1344) filter(1198) }
{ general(901) number(790) one(736) }
{ risk(3053) factor(974) diseas(938) }
{ cancer(2502) breast(956) screen(824) }
{ estim(2440) model(1874) function(577) }
{ bind(1733) structur(1185) ligand(1036) }
{ chang(1828) time(1643) increas(1301) }
{ method(984) reconstruct(947) comput(926) }
{ import(1318) role(1303) understand(862) }
{ compound(1573) activ(1297) structur(1058) }
{ signal(2180) analysi(812) frequenc(800) }
{ sampl(1606) size(1419) use(1276) }
{ high(1669) rate(1365) level(1280) }
{ network(2748) neural(1063) input(814) }
{ studi(2440) review(1878) systemat(933) }
{ treatment(1704) effect(941) patient(846) }
{ error(1145) method(1030) estim(1020) }
{ concept(1167) ontolog(924) domain(897) }
{ method(1557) propos(1049) approach(1037) }
{ featur(1941) imag(1645) propos(1176) }
{ howev(809) still(633) remain(590) }
{ studi(1410) differ(1259) use(1210) }
{ spatial(1525) area(1432) region(1030) }
{ group(2977) signific(1463) compar(1072) }
{ data(3008) multipl(1320) sourc(1022) }
{ analysi(2126) use(1163) compon(1037) }
{ use(1733) differ(960) four(931) }
{ decis(3086) make(1611) patient(1517) }
{ process(1125) use(805) approach(778) }
{ activ(1452) weight(1219) physic(1104) }
{ detect(2391) sensit(1101) algorithm(908) }
{ model(3404) distribut(989) bayesian(671) }
{ imag(1947) propos(1133) code(1026) }
{ inform(2794) health(2639) internet(1427) }
{ system(1976) rule(880) can(841) }
{ measur(2081) correl(1212) valu(896) }
{ imag(1057) registr(996) error(939) }
{ sequenc(1873) structur(1644) protein(1328) }
{ method(1219) similar(1157) match(930) }
{ featur(3375) classif(2383) classifi(1994) }
{ patient(2315) diseas(1263) diabet(1191) }
{ take(945) account(800) differ(722) }
{ motion(1329) object(1292) video(1091) }
{ assess(1506) score(1403) qualiti(1306) }
{ surgeri(1148) surgic(1085) robot(1054) }
{ framework(1458) process(801) describ(734) }
{ problem(2511) optim(1539) algorithm(950) }
{ learn(2355) train(1041) set(1003) }
{ clinic(1479) use(1117) guidelin(835) }
{ algorithm(1844) comput(1787) effici(935) }
{ extract(1171) text(1153) clinic(932) }
{ data(1714) softwar(1251) tool(1186) }
{ design(1359) user(1324) use(1319) }
{ control(1307) perform(991) simul(935) }
{ care(1570) inform(1187) nurs(1089) }
{ search(2224) databas(1162) retriev(909) }
{ case(1353) use(1143) diagnosi(1136) }
{ data(3963) clinic(1234) research(1004) }
{ perform(999) metric(946) measur(919) }
{ research(1085) discuss(1038) issu(1018) }
{ system(1050) medic(1026) inform(1018) }
{ model(2341) predict(2261) use(1141) }
{ perform(1367) use(1326) method(1137) }
{ record(1888) medic(1808) patient(1693) }
{ health(3367) inform(1360) care(1135) }
{ model(3480) simul(1196) paramet(876) }
{ monitor(1329) mobil(1314) devic(1160) }
{ ehr(2073) health(1662) electron(1139) }
{ state(1844) use(1261) util(961) }
{ research(1218) medic(880) student(794) }
{ patient(2837) hospit(1953) medic(668) }
{ model(2656) set(1616) predict(1553) }
{ data(2317) use(1299) case(1017) }
{ age(1611) year(1155) adult(843) }
{ medic(1828) order(1363) alert(1069) }
{ cost(1906) reduc(1198) effect(832) }
{ gene(2352) biolog(1181) express(1162) }
{ first(2504) two(1366) second(1323) }
{ intervent(3218) particip(2042) group(1664) }
{ time(1939) patient(1703) rate(768) }
{ patient(1821) servic(1111) care(1106) }
{ use(2086) technolog(871) perceiv(783) }
{ can(981) present(881) function(850) }
{ health(1844) social(1437) communiti(874) }
{ structur(1116) can(940) graph(676) }
{ use(976) code(926) identifi(902) }
{ drug(1928) target(777) effect(648) }
{ result(1111) use(1088) new(759) }
{ implement(1333) system(1263) develop(1122) }
{ survey(1388) particip(1329) question(1065) }
{ method(1969) cluster(1462) data(1082) }
{ method(2212) result(1239) propos(1039) }


The identification of regions prone to atherogenesis in the arterial network is compounded by the complex, slow interaction of mechanical and biomechanical processes. In recent times simplifications to the analysis of the near wall hemodynamics have been sought-after to identify plaque prone regions. Mean parameters have been defined to analyze the common fluid mechanical hypotheses considering the role of wall shear stress (WSS) variations in the pathological changes to the endothelium. In this study well known WSS indicators are applied to varying flow conditions of blood-like fluids in a 90-degree arterial bifurcation. The conventional indicators identify two distinct, focal regions that correlate with a known plaque prone location near arterial bifurcations. The results however demonstrate that the interpretation of the indicators can be difficult under varying flow conditions unless complementary parameters are considered simultaneously. A new indicator is also suggested that extracts the peaks of the temporal WSS gradients (PTWSSGs) and is shown to co-incide well with plaque prone regions. The PTWSSG could be used as a complimentary atherogenic indicator in bifurcating arteries, thereby expanding cardiovascular disease studies to the consideration of alternative fluid mechanical hypotheses. The inclusion of a non-Newtonian model is important in predicting the WSS and temporal WSS gradient distributions near the bifurcation due to the separation bubble induced fluctuations in the shear. Atherogenic indicators could be misleading if non-Newtonian effects are excluded.

Resumo Limpo

identif region prone atherogenesi arteri network compound complex slow interact mechan biomechan process recent time simplif analysi near wall hemodynam soughtaft identifi plaqu prone region mean paramet defin analyz common fluid mechan hypothes consid role wall shear stress wss variat patholog chang endothelium studi well known wss indic appli vari flow condit bloodlik fluid degre arteri bifurc convent indic identifi two distinct focal region correl known plaqu prone locat near arteri bifurc result howev demonstr interpret indic can difficult vari flow condit unless complementari paramet consid simultan new indic also suggest extract peak tempor wss gradient ptwssgs shown coincid well plaqu prone region ptwssg use complimentari atherogen indic bifurc arteri therebi expand cardiovascular diseas studi consider altern fluid mechan hypothes inclus nonnewtonian model import predict wss tempor wss gradient distribut near bifurc due separ bubbl induc fluctuat shear atherogen indic mislead nonnewtonian effect exclud

Resumos Similares

J Clin Monit Comput - Impact of central hypovolemia on photoplethysmographic waveform parameters in healthy volunteers. Part 1: time domain analysis. ( 0,80776551748905 )
Wiley Interdiscip Rev Syst Biol Med - Integration of cardiovascular regulation by the blood/endothelium cell-free layer. ( 0,776244060837771 )
Med Biol Eng Comput - Cardiac oxygen supply is compromised during the night in hypertensive patients. ( 0,758398739747113 )
Comput Methods Programs Biomed - Computer simulation of MHD blood conveying gold nanoparticles as a third grade non-Newtonian nanofluid in a hollow porous vessel. ( 0,750382913447688 )
J Clin Monit Comput - Impact of skin incision on the pleth variability index. ( 0,745939156337325 )
IEEE J Biomed Health Inform - Experimental investigation of the influence of the aortic stiffness on hemodynamics in the ascending aorta. ( 0,744149748328598 )
Med Biol Eng Comput - Model-based correction of the influence of body position on continuous segmental and hand-to-foot bioimpedance measurements. ( 0,743398768549397 )
Int J Med Robot - Haemodynamics and cardiac function during robotic-assisted laparoscopic prostatectomy in steep Trendelenburg position. ( 0,742963721484226 )
J Clin Monit Comput - USCOM-window to the circulation: utility of supra-sternal Doppler in an elderly anaesthetized patient for a robotic cystectomy. ( 0,738220165273332 )
Comput Math Methods Med - A new high-resolution spectral approach to noninvasively evaluate wall deformations in arteries. ( 0,735987675411725 )
J Clin Monit Comput - The effect of endotracheal tube cuff pressure change during gynecological laparoscopic surgery on postoperative sore throat: a control study. ( 0,729421309847831 )
J Clin Monit Comput - Transesophageal echocardiography and intraoperative phlebotomy during surgical repair of coarctation of aorta in a patient with atrial septal defect, moderately severe mitral regurgitation and severe pulmonary hypertension. ( 0,72672620674444 )
Med Biol Eng Comput - A coupled flow-acoustic computational study of bruits from a modeled stenosed artery. ( 0,72463818146143 )
J Clin Monit Comput - Pulmonary artery pulsatility is the main cause of cardiogenic oscillations. ( 0,724487582242994 )
Comput Math Methods Med - Numerical study for blood flow in pulmonary arteries after repair of tetralogy of Fallot. ( 0,724355822800294 )
Comput. Biol. Med. - Biomechanical behaviors of curved artery with flexible wall: a numerical study using fluid-structure interaction method. ( 0,72375070403295 )
J Clin Monit Comput - Continuous measurement of cardiac output with the electrical velocimetry method in patients under spinal anesthesia for cesarean delivery. ( 0,723380661963749 )
Med Biol Eng Comput - The consequences of the mechanical environment of peripheral arteries for nitinol stenting. ( 0,722402627527299 )
J Clin Monit Comput - Changes in R-Wave amplitude in DII lead is less sensitive than pulse pressure variation to detect changes in stroke volume after fluid challenge in ICU patients postoperatively to cardiac surgery. ( 0,721655334696363 )
Comput. Biol. Med. - A semi-automated computer tool for the analysis of retinal vessel diameter dynamics. ( 0,72026169397325 )
J Clin Monit Comput - Noninvasive continuous hemodynamic monitoring. ( 0,719631544035687 )
Comput Methods Programs Biomed - Simulation of transport and extravasation of nanoparticles in tumors which exhibit enhanced permeability and retention effect. ( 0,71927581206953 )
Comput. Biol. Med. - Simulation of a pulsatile non-Newtonian flow past a stenosed 2D artery with atherosclerosis. ( 0,717630313593662 )
J Clin Monit Comput - Assessment of the effect of rapid crystalloid infusion on stroke volume variation and pleth variability index after a preoperative fast. ( 0,714268245630986 )
J Clin Monit Comput - Detection of changes in muscle oxygen saturation in the human leg: a comparison of two near-infrared spectroscopy devices. ( 0,712518812505579 )
J Clin Monit Comput - A model-based decision support system for critiquing mechanical ventilation treatments. ( 0,712511913475156 )
Comput Math Methods Med - Simulation of the Frank-Starling Law of the Heart. ( 0,712382110515258 )
Med Biol Eng Comput - Computational model for estimating the short- and long-term cardiac response to arteriovenous fistula creation for hemodialysis. ( 0,710618162490366 )
Wiley Interdiscip Rev Syst Biol Med - Multiscale models of thrombogenesis. ( 0,709726823839597 )
Comput Methods Programs Biomed - In silico study of the haemodynamic effects induced by mechanical ventilation and biventricular pacemaker. ( 0,709438457830032 )
J Clin Monit Comput - Comparison of cardiac output determined by bioimpedance and bioreactance methods at rest and during exercise. ( 0,707946962684747 )
J Clin Monit Comput - Radial-femoral concordance in time and frequency domain-based estimates of systemic arterial respiratory variation. ( 0,707609542684464 )
Comput. Biol. Med. - The hemodynamic alterations induced by the vascular angular deformation in stent-assisted coiling of bifurcation aneurysms. ( 0,707362527774058 )
Comput Math Methods Med - Computational fluid dynamics analysis of the effect of plaques in the left coronary artery. ( 0,707353031161342 )
Comput Methods Programs Biomed - Impact of pulmonary vascular stiffness and vasodilator treatment in pediatric pulmonary hypertension: 21 patient-specific fluid-structure interaction studies. ( 0,706752245895146 )
J Clin Monit Comput - Heart sounds analysis via esophageal stethoscope system in beagles. ( 0,705903957726641 )
Comput. Biol. Med. - Computational study of thermal effects of large blood vessels in human knee joint. ( 0,705401926763294 )
J Clin Monit Comput - Thoracic impedance measures tissue characteristics in the vicinity of the electrodes, not intervening lung water: implications for heart failure monitoring. ( 0,705158858045102 )
Methods Inf Med - Extraction of response waveforms of heartbeat and blood pressure to swallowing. Using mixed signal processing of time domain and respiratory phase domain. ( 0,704805342461408 )
Comput Math Methods Med - Mathematical modeling of radiofrequency ablation for varicose veins. ( 0,703927139134201 )
J Clin Monit Comput - Evaluation of mean systemic filling pressure from pulse contour cardiac output and central venous pressure. ( 0,703679087186758 )
J Clin Monit Comput - Assessment of cerebral oxygenation using near infrared spectroscopy during isovolemic hemodilution in pediatric patients. ( 0,702372503181062 )
Med Biol Eng Comput - Evaluation of the hemodynamics in straight 6-mm and tapered 6- to 8-mm grafts as upper arm hemodialysis vascular access. ( 0,702335624339896 )
Comput Math Methods Med - Computational fluid dynamics simulations of contrast agent bolus dispersion in a coronary bifurcation: impact on MRI-based quantification of myocardial perfusion. ( 0,702097822363884 )
J Med Syst - Mathematical models of real geometrical factors in restricted blood vessels for the analysis of CAD (coronary artery diseases) using Legendre, Boubaker and Bessel polynomials. ( 0,701795496046914 )
Med Biol Eng Comput - Arterial reservoir-excess pressure and ventricular work. ( 0,701675950497564 )
Comput Methods Programs Biomed - Measurements of the left atrium and pulmonary veins for analysis of reverse structural remodeling following cardiac ablation therapy. ( 0,701099009482529 )
J Clin Monit Comput - Hemodynamic volumetry using transpulmonary ultrasound dilution (TPUD) technology in a neonatal animal model. ( 0,700447419077311 )
J Clin Monit Comput - Combination of continuous pulse pressure variation monitoring and cardiac filling pressure to predict fluid responsiveness. ( 0,699577511964191 )
J Clin Monit Comput - Continuous minimally invasive peri-operative monitoring of cardiac output by pulmonary capnotracking: comparison with thermodilution and transesophageal echocardiography. ( 0,699046061366036 )
Med Biol Eng Comput - Timing and size of flow impingement in a giant intracranial aneurysm at the internal carotid artery. ( 0,698973672212729 )
Med Biol Eng Comput - The effect of aortic wall and aortic leaflet stiffening on coronary hemodynamic: a fluid-structure interaction study. ( 0,698637204618596 )
Comput Math Methods Med - Evaluation of a model-based hemodynamic monitoring method in a porcine study of septic shock. ( 0,698169944181477 )
Med Biol Eng Comput - Mechanical behaviour and rupture of normal and pathological human ascending aortic wall. ( 0,695892497745069 )
J Clin Monit Comput - Decrease in pulmonary artery pressure after administration of thoracic epidural anesthesia in a patient with Marfan syndrome awaiting aortic valve replacement procedure. ( 0,695322669360202 )
Comput. Biol. Med. - Effects of blood in veins of dragonfly wing on the vibration characteristics. ( 0,69449295490858 )
J Clin Monit Comput - Transthoracic electrical bioimpedence cardiac output: comparison with multigated equillibrium radionuclide cardiography. ( 0,692118408140229 )
Comput. Aided Surg. - Kinematics and laxity of a linked total elbow arthroplasty following computer navigated implant positioning. ( 0,691675671399913 )
Int J Comput Assist Radiol Surg - High-sensitive fluorescence endoscope using electrocardiograph-synchronized multiple exposure. ( 0,690251887398118 )
J Clin Monit Comput - Cardiopulmonary interactions and volume status assessment. ( 0,688662391456163 )
Med Biol Eng Comput - Characterization of skin dermis microcirculation in flow-mediated dilation using optical sensor with pressurization mechanism. ( 0,688627935371017 )
J Clin Monit Comput - States of low pulmonary blood flow can be detected non-invasively at the bedside measuring alveolar dead space. ( 0,688478104837282 )
J Clin Monit Comput - Arterial pressure waveform derived cardiac output FloTrac/Vigileo system (third generation software): comparison of two monitoring sites with the thermodilution cardiac output. ( 0,687715608231584 )
Comput Math Methods Med - Mathematical analysis of non-Newtonian blood flow in stenosis narrow arteries. ( 0,687712670368372 )
J Clin Monit Comput - Tako-tsubo cardiomyopathy and microcirculation. ( 0,686487542402796 )
J Clin Monit Comput - Bedside assessment of passive leg raising effects on venous return. ( 0,685741280548974 )
Comput Methods Programs Biomed - A model of perfusion of the healthy human lung. ( 0,685671390005246 )
Med Biol Eng Comput - Determinants of vascular and cardiac baroreflex sensitivity values in a random population sample. ( 0,685180103677066 )
Comput Math Methods Med - Plasma volume expansion resulting from intravenous glucose tolerance test. ( 0,68442121470456 )
Comput. Biol. Med. - Computational estimation of fluid mechanical benefits from a fluid deflector at the distal end of artificial vascular grafts. ( 0,683235492807839 )
Comput Methods Programs Biomed - Mechanical ventilation and thoracic artificial lung assistance during mechanical circulatory support with PUCA pump: in silico study. ( 0,681670135876085 )
J Clin Monit Comput - Fluid responsiveness is about stroke volume, and not pulse pressure Yogi: the power of Doppler fluid management and cardiovascular monitoring. ( 0,6796241332123 )
J Clin Monit Comput - Respiratory and non-respiratory sinus arrhythmia: implications for heart rate variability. ( 0,679268126505302 )
Med Biol Eng Comput - Electropermeabilization of endocytotic vesicles in B16 F1 mouse melanoma cells. ( 0,678642142091219 )
Med Biol Eng Comput - Coronary-aortic interaction during ventricular isovolumic contraction. ( 0,678420092932327 )
Comput. Biol. Med. - Numerical investigation of blood flow in three-dimensional porcine left anterior descending artery with various stenoses. ( 0,677510843760859 )
J Clin Monit Comput - Hemodynamic management of cardiovascular failure by using PCO(2) venous-arterial difference. ( 0,6772127133309 )
Comput Math Methods Med - Therapeutic vascular compliance change may cause significant variation in coronary perfusion: a numerical study. ( 0,677060533627853 )
Med Biol Eng Comput - Monitoring intracellular, interstitial, and intravascular volume changes during fluid management procedures. ( 0,676802040613538 )
Med Biol Eng Comput - On the reliability of frequency components in systolic arterial pressure in patients with atrial fibrillation. ( 0,675729507213534 )
J Clin Monit Comput - In-line pressure within a HOTLINE? Fluid Warmer, under various flow conditions. ( 0,674935363070893 )
J Clin Monit Comput - Capability of a new paediatric oesophageal Doppler monitor to detect changes in cardiac output during testing of external pacemakers after cardiac surgery. ( 0,674851742310541 )
J Clin Monit Comput - Impact of central hypovolemia on photoplethysmographic waveform parameters in healthy volunteers part 2: frequency domain analysis. ( 0,674799070726773 )
Comput. Biol. Med. - Fluid-dynamics modelling of the human left ventricle with dynamic mesh for normal and myocardial infarction: preliminary study. ( 0,674746546575439 )
J Clin Monit Comput - Validation of the new Complior sensor to record pressure signals non-invasively. ( 0,67470778971887 )
J Clin Monit Comput - Variations in the pre-ejection period induced by deep breathing do not predict the hemodynamic response to early haemorrhage in healthy volunteers. ( 0,672989350671184 )
Med Biol Eng Comput - Effect of respiration on Korotkoff sounds and oscillometric cuff pressure pulses during blood pressure measurement. ( 0,672557061517466 )
Med Biol Eng Comput - Effects of a carotid covered stent with a novel membrane design on the blood flow regime and hemodynamic parameters distribution at the carotid artery bifurcation. ( 0,671812941866951 )
Med Biol Eng Comput - Investigation of photoplethysmographic signals and blood oxygen saturation values on healthy volunteers during cuff-induced hypoperfusion using a multimode PPG/SpO2 sensor. ( 0,670798413448007 )
Comput. Biol. Med. - Computational analysis of the importance of flow synchrony for cardiac ventricular assist devices. ( 0,670439958098735 )
Med Biol Eng Comput - The influence of intraluminal thrombus on noninvasive abdominal aortic aneurysm wall distensibility measurement. ( 0,670382377928504 )
J Clin Monit Comput - Bench test assessment of mainstream capnography during high frequency oscillatory ventilation. ( 0,669455175800288 )
J Clin Monit Comput - An evaluation and comparison of intraventricular, intraparenchymal, and fluid-coupled techniques for intracranial pressure monitoring in patients with severe traumatic brain injury. ( 0,668814872693277 )
J Clin Monit Comput - The changes of pulmonary blood flow in non-ventilated lung during one lung ventilation. ( 0,667620432459055 )
Comput Math Methods Med - Evaluating the hemodynamical response of a cardiovascular system under support of a continuous flow left ventricular assist device via numerical modeling and simulations. ( 0,66715762646507 )
Wiley Interdiscip Rev Syst Biol Med - Lymphatic vessels in health and disease. ( 0,666996128839813 )
J Clin Monit Comput - Non-invasive cardiac output and oxygen delivery measurement in an infant with critical anemia. ( 0,665213255143222 )
Med Biol Eng Comput - Assessment of dynamic cerebral autoregulation and cerebral carbon dioxide reactivity during normothermic cardiopulmonary bypass. ( 0,663499546506885 )
J Med Syst - Human cardiovascular model and applications. ( 0,662856228107901 )
Comput Methods Programs Biomed - Quantitative analysis of digital subtraction angiography using optical flow method on occlusive cerebrovascular disease. ( 0,662831748375997 )