Comput. Biol. Med. - Accurate tumor localization and tracking in radiation therapy using wireless body sensor networks.

Tópicos

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Resumo

Radiation therapy is an effective method to combat cancerous tumors by killing the malignant cells or controlling their growth. Knowing the exact position of the tumor is a very critical prerequisite in radiation therapy. Since the position of the tumor changes during the process of radiation therapy due to the patients movements and respiration, a real-time tumor tracking method is highly desirable in order to deliver a sufficient dose of radiation to the tumor region without damaging the surrounding healthy tissues. In this paper, we develop a novel tumor positioning method based on spatial sparsity. We estimate the position by processing the received signals from only one implantable RF transmitter. The proposed method uses less number of sensors compared to common magnetic transponder based approaches. The performance of the proposed method is evaluated in two different cases: (1) when the tissue configuration is perfectly determined (acquired beforehand by MRI or CT) and (2) when there are some uncertainties about the tissue boundaries. The results demonstrate the high accuracy and performance of the proposed method, even when the tissue boundaries are imperfectly known.

Resumo Limpo

radiat therapi effect method combat cancer tumor kill malign cell control growth know exact posit tumor critic prerequisit radiat therapi sinc posit tumor chang process radiat therapi due patient movement respir realtim tumor track method high desir order deliv suffici dose radiat tumor region without damag surround healthi tissu paper develop novel tumor posit method base spatial sparsiti estim posit process receiv signal one implant rf transmitt propos method use less number sensor compar common magnet transpond base approach perform propos method evalu two differ case tissu configur perfect determin acquir beforehand mri ct uncertainti tissu boundari result demonstr high accuraci perform propos method even tissu boundari imperfect known

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