Comput. Biol. Med. - Finding splitting lines for touching cell nuclei with a shortest path algorithm.

Tópicos

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Resumo

A shortest path-based algorithm is proposed in this paper to find splitting lines for touching cell nuclei. First, an initial splitting line is obtained through the distance transform of a marker image and the watershed algorithm. The initial splitting line is then separated into different line segments as necessary, and the endpoint positions of these line segments are adjusted to the concave points on the contour. Finally, a shortest path algorithm is used to find the accurate splitting line between the starting-point and the end-point, and the final split can be achieved by the contour of the touching cell nuclei and the splitting lines. Comparisons of experimental results show that the proposed algorithm is effective for segmentation of different types of touching cell nuclei.

Resumo Limpo

shortest pathbas algorithm propos paper find split line touch cell nuclei first initi split line obtain distanc transform marker imag watersh algorithm initi split line separ differ line segment necessari endpoint posit line segment adjust concav point contour final shortest path algorithm use find accur split line startingpoint endpoint final split can achiev contour touch cell nuclei split line comparison experiment result show propos algorithm effect segment differ type touch cell nuclei

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