Comput. Biol. Med. - Automatic brain extraction methods for T1 magnetic resonance images using region labeling and morphological operations.


{ imag(2675) segment(2577) method(1081) }
{ first(2504) two(1366) second(1323) }
{ learn(2355) train(1041) set(1003) }
{ can(774) often(719) complex(702) }
{ method(1219) similar(1157) match(930) }
{ result(1111) use(1088) new(759) }
{ imag(1057) registr(996) error(939) }
{ error(1145) method(1030) estim(1020) }
{ concept(1167) ontolog(924) domain(897) }
{ network(2748) neural(1063) input(814) }
{ data(3963) clinic(1234) research(1004) }
{ detect(2391) sensit(1101) algorithm(908) }
{ imag(1947) propos(1133) code(1026) }
{ algorithm(1844) comput(1787) effici(935) }
{ extract(1171) text(1153) clinic(932) }
{ method(1557) propos(1049) approach(1037) }
{ perform(1367) use(1326) method(1137) }
{ group(2977) signific(1463) compar(1072) }
{ activ(1138) subject(705) human(624) }
{ analysi(2126) use(1163) compon(1037) }
{ sequenc(1873) structur(1644) protein(1328) }
{ featur(3375) classif(2383) classifi(1994) }
{ patient(2315) diseas(1263) diabet(1191) }
{ take(945) account(800) differ(722) }
{ motion(1329) object(1292) video(1091) }
{ surgeri(1148) surgic(1085) robot(1054) }
{ problem(2511) optim(1539) algorithm(950) }
{ data(1714) softwar(1251) tool(1186) }
{ method(984) reconstruct(947) comput(926) }
{ case(1353) use(1143) diagnosi(1136) }
{ model(2341) predict(2261) use(1141) }
{ visual(1396) interact(850) tool(830) }
{ health(3367) inform(1360) care(1135) }
{ age(1611) year(1155) adult(843) }
{ time(1939) patient(1703) rate(768) }
{ patient(1821) servic(1111) care(1106) }
{ structur(1116) can(940) graph(676) }
{ high(1669) rate(1365) level(1280) }
{ estim(2440) model(1874) function(577) }
{ activ(1452) weight(1219) physic(1104) }
{ model(3404) distribut(989) bayesian(671) }
{ data(1737) use(1416) pattern(1282) }
{ inform(2794) health(2639) internet(1427) }
{ system(1976) rule(880) can(841) }
{ measur(2081) correl(1212) valu(896) }
{ bind(1733) structur(1185) ligand(1036) }
{ imag(2830) propos(1344) filter(1198) }
{ studi(2440) review(1878) systemat(933) }
{ assess(1506) score(1403) qualiti(1306) }
{ treatment(1704) effect(941) patient(846) }
{ framework(1458) process(801) describ(734) }
{ chang(1828) time(1643) increas(1301) }
{ clinic(1479) use(1117) guidelin(835) }
{ design(1359) user(1324) use(1319) }
{ control(1307) perform(991) simul(935) }
{ model(2220) cell(1177) simul(1124) }
{ care(1570) inform(1187) nurs(1089) }
{ general(901) number(790) one(736) }
{ search(2224) databas(1162) retriev(909) }
{ featur(1941) imag(1645) propos(1176) }
{ howev(809) still(633) remain(590) }
{ studi(1410) differ(1259) use(1210) }
{ risk(3053) factor(974) diseas(938) }
{ perform(999) metric(946) measur(919) }
{ research(1085) discuss(1038) issu(1018) }
{ system(1050) medic(1026) inform(1018) }
{ import(1318) role(1303) understand(862) }
{ compound(1573) activ(1297) structur(1058) }
{ studi(1119) effect(1106) posit(819) }
{ blood(1257) pressur(1144) flow(957) }
{ spatial(1525) area(1432) region(1030) }
{ record(1888) medic(1808) patient(1693) }
{ model(3480) simul(1196) paramet(876) }
{ monitor(1329) mobil(1314) devic(1160) }
{ ehr(2073) health(1662) electron(1139) }
{ state(1844) use(1261) util(961) }
{ research(1218) medic(880) student(794) }
{ patient(2837) hospit(1953) medic(668) }
{ model(2656) set(1616) predict(1553) }
{ data(2317) use(1299) case(1017) }
{ medic(1828) order(1363) alert(1069) }
{ signal(2180) analysi(812) frequenc(800) }
{ cost(1906) reduc(1198) effect(832) }
{ sampl(1606) size(1419) use(1276) }
{ gene(2352) biolog(1181) express(1162) }
{ data(3008) multipl(1320) sourc(1022) }
{ intervent(3218) particip(2042) group(1664) }
{ use(2086) technolog(871) perceiv(783) }
{ can(981) present(881) function(850) }
{ health(1844) social(1437) communiti(874) }
{ cancer(2502) breast(956) screen(824) }
{ use(976) code(926) identifi(902) }
{ use(1733) differ(960) four(931) }
{ drug(1928) target(777) effect(648) }
{ implement(1333) system(1263) develop(1122) }
{ survey(1388) particip(1329) question(1065) }
{ decis(3086) make(1611) patient(1517) }
{ process(1125) use(805) approach(778) }
{ method(1969) cluster(1462) data(1082) }
{ method(2212) result(1239) propos(1039) }


In this work we propose two brain extraction methods (BEM) that solely depend on the brain anatomy and its intensity characteristics. Our methods are simple, unsupervised and knowledge based. Using an adaptive intensity thresholding method on the magnetic resonance images of head scans, a binary image is obtained. The binary image is labeled using the anatomical facts that the scalp is the boundary between head and background, and the skull is the boundary separating brain and scalp. A run length scheme is applied on the labeled image to get a rough brain mask. Morphological operations are then performed to obtain the fine brain on the assumption that brain is the largest connected component (LCC). But the LCC concept failed to work on some slices where brain is composed of more than one connected component. To solve this problem a 3-D approach is introduced in the BEM. Experimental results on 61 sets of T1 scans taken from MRI scan center and neuroimage web services showed that our methods give better results than the popular methods, FSL's Brain Extraction Tool (BET), BrainSuite's Brain Surface Extractor (BSE) gives results comparable to that of Model-based Level Sets (MLS) and works well even where MLS failed. The average Dice similarity index computed using the "Gold standard" and the specificity values are 0.938 and 0.992, respectively, which are higher than that for BET, BSE and MLS. The average processing time by one of our methods is ?1s/slice, which is smaller than for MLS, which is ?4s/slice. One of our methods produces the lowest false positive rate of 0.075, which is smaller than that for BSE, BET and MLS. It is independent of imaging orientation and works well for slices with abnormal features like tumor and lesion in which the existing methods fail in certain cases.

Resumo Limpo

work propos two brain extract method bem sole depend brain anatomi intens characterist method simpl unsupervis knowledg base use adapt intens threshold method magnet reson imag head scan binari imag obtain binari imag label use anatom fact scalp boundari head background skull boundari separ brain scalp run length scheme appli label imag get rough brain mask morpholog oper perform obtain fine brain assumpt brain largest connect compon lcc lcc concept fail work slice brain compos one connect compon solv problem d approach introduc bem experiment result set t scan taken mri scan center neuroimag web servic show method give better result popular method fsls brain extract tool bet brainsuit brain surfac extractor bse give result compar modelbas level set mls work well even mls fail averag dice similar index comput use gold standard specif valu respect higher bet bse mls averag process time one method sslice smaller mls sslice one method produc lowest fals posit rate smaller bse bet mls independ imag orient work well slice abnorm featur like tumor lesion exist method fail certain case

Resumos Similares

Comput Math Methods Med - A hybrid approach of using symmetry technique for brain tumor segmentation. ( 0,902206398599843 )
Comput. Biol. Med. - Refinement of lung nodule candidates based on local geometric shape analysis and Laplacian of Gaussian kernels. ( 0,893876831695437 )
Comput. Biol. Med. - Retinal vessel segmentation using a multi-scale medialness function. ( 0,889950421824276 )
Int J Comput Assist Radiol Surg - Automatic 3D segmentation of individual facial muscles using unlabeled prior information. ( 0,888931083596865 )
IEEE J Biomed Health Inform - A spatiotemporal-based scheme for efficient registration-based segmentation of thoracic 4-D MRI. ( 0,886441368347148 )
Int J Comput Assist Radiol Surg - 3D variational brain tumor segmentation using Dirichlet priors on a clustered feature set. ( 0,883350191596706 )
Comput. Biol. Med. - Nearly automated motion artifacts correction between multi breath-hold short-axis and long-axis cine CMR images. ( 0,882133218157757 )
Int J Comput Assist Radiol Surg - Computer-aided nidus segmentation and angiographic characterization of arteriovenous malformations. ( 0,877800853730104 )
Comput. Biol. Med. - 3D geometric split-merge segmentation of brain MRI datasets. ( 0,872943269399834 )
Med Biol Eng Comput - A fully automated human knee 3D MRI bone segmentation using the ray casting technique. ( 0,872558676005589 )
Int J Comput Assist Radiol Surg - Nasopharyngeal carcinoma segmentation using a region growing technique. ( 0,868956704402681 )
Comput Methods Programs Biomed - MARGA: multispectral adaptive region growing algorithm for brain extraction on axial MRI. ( 0,866446544141479 )
Comput Math Methods Med - A hybrid method for pancreas extraction from CT image based on level set methods. ( 0,865054980593638 )
IEEE Trans Image Process - Incorporating anatomical side information into PET reconstruction using nonlocal regularization. ( 0,864917273392471 )
Int J Comput Assist Radiol Surg - Fetal brain volumetry through MRI volumetric reconstruction and segmentation. ( 0,86441172497909 )
Med Biol Eng Comput - Automatic segmentation of brain MR images using an adaptive balloon snake model with fuzzy classification. ( 0,864142671997389 )
Int J Comput Assist Radiol Surg - Automatic lung segmentation method for MRI-based lung perfusion studies of patients with chronic obstructive pulmonary disease. ( 0,863737172196299 )
Comput Methods Programs Biomed - Segmentation of pituitary adenoma: a graph-based method vs. a balloon inflation method. ( 0,861147089915651 )
Comput Methods Programs Biomed - A novel method for pulmonary embolism detection in CTA images. ( 0,861103064401929 )
Comput Methods Programs Biomed - pSnakes: a new radial active contour model and its application in the segmentation of the left ventricle from echocardiographic images. ( 0,860133651506517 )
Int J Comput Assist Radiol Surg - Automated aorta segmentation in low-dose chest CT images. ( 0,856882152405929 )
Int J Comput Assist Radiol Surg - Automatic segmentation of the nasal cavity and paranasal sinuses from cone-beam CT images. ( 0,854385608323675 )
Comput. Biol. Med. - Lung nodule segmentation and recognition using SVM classifier and active contour modeling: a complete intelligent system. ( 0,852950130931773 )
Int J Comput Assist Radiol Surg - Acetabular cartilage segmentation in CT arthrography based on a bone-normalized probabilistic atlas. ( 0,852453511112586 )
Int J Comput Assist Radiol Surg - Vertebra identification using template matching modelmp and K-means clustering. ( 0,851969185563876 )
Int J Comput Assist Radiol Surg - Spatially adaptive active contours: a semi-automatic tumor segmentation framework. ( 0,848780402282465 )
Comput Methods Programs Biomed - A survey of prostate segmentation methodologies in ultrasound, magnetic resonance and computed tomography images. ( 0,847233099568137 )
IEEE J Biomed Health Inform - Segmentation of tumor and edema along with healthy tissues of brain using wavelets and neural networks. ( 0,846989138775645 )
Int J Comput Assist Radiol Surg - Segmentation of iodine brachytherapy implants in fluoroscopy. ( 0,846399708249871 )
Comput. Biol. Med. - A level-set based approach for anterior teeth segmentation in cone beam computed tomography images. ( 0,846231175957805 )
Comput Methods Programs Biomed - A review of atlas-based segmentation for magnetic resonance brain images. ( 0,846052859937707 )
Comput. Biol. Med. - Phase-based probabilistic active contour for nerve detection in ultrasound images for regional anesthesia. ( 0,845167314665852 )
IEEE Trans Image Process - Overlapping cell nuclei segmentation using a spatially adaptive active physical model. ( 0,845093570388182 )
Med Biol Eng Comput - Automatic segmentation of carotid B-mode images using fuzzy classification. ( 0,844985116504185 )
Int J Comput Assist Radiol Surg - PNist: interactive volumetric measurements of plexiform neurofibromas in MRI scans. ( 0,844893611849485 )
Int J Comput Assist Radiol Surg - Liver segmentation for contrast-enhanced MR images using partitioned probabilistic model. ( 0,844815388196932 )
Comput. Biol. Med. - Segmentation of anterior cruciate ligament in knee MR images using graph cuts with patient-specific shape constraints and label refinement. ( 0,844634841777164 )
Comput Math Methods Med - Segmentation of brain MRI using SOM-FCM-based method and 3D statistical descriptors. ( 0,842037289999631 )
Comput. Biol. Med. - Reducing redundancy in wireless capsule endoscopy videos. ( 0,841766910026654 )
Med Biol Eng Comput - Automatic segmentation of the fetal cerebellum on ultrasound volumes, using a 3D statistical shape model. ( 0,837080498264751 )
Int J Comput Assist Radiol Surg - Extreme leg motion analysis of professional ballet dancers via MRI segmentation of multiple leg postures. ( 0,835109307479669 )
Int J Comput Assist Radiol Surg - Automated segmentation of basal ganglia and deep brain structures in MRI of Parkinson's disease. ( 0,834291845627998 )
Int J Comput Assist Radiol Surg - Voxel classification and graph cuts for automated segmentation of pathological periprosthetic hip anatomy. ( 0,831099690559901 )
Comput. Biol. Med. - Accurate tumor localization and tracking in radiation therapy using wireless body sensor networks. ( 0,830946765011441 )
Comput Math Methods Med - Diabetic retinopathy grading by digital curvelet transform. ( 0,828414353159604 )
Int J Comput Assist Radiol Surg - Statistical model-based segmentation of the proximal femur in digital antero-posterior (AP) pelvic radiographs. ( 0,827939181188714 )
Int J Comput Assist Radiol Surg - Automatic left ventricle segmentation in volumetric SPECT data set by variational level set. ( 0,827414911565075 )
Int J Comput Assist Radiol Surg - GPU accelerated segmentation and centerline extraction of tubular structures from medical images. ( 0,82579529834264 )
IEEE J Biomed Health Inform - Segmentation of the blood vessels and optic disk in retinal images. ( 0,825204473773176 )
Int J Comput Assist Radiol Surg - Carotid vasculature modeling from patient CT angiography studies for interventional procedures simulation. ( 0,825201459268237 )
BMC Med Inform Decis Mak - Automatic segmentation of meningioma from non-contrasted brain MRI integrating fuzzy clustering and region growing. ( 0,823365571524303 )
Int J Comput Assist Radiol Surg - Expert-driven label fusion in multi-atlas-based segmentation of the prostate using weighted atlases. ( 0,821819079356177 )
Comput Methods Programs Biomed - Automatic multiple sclerosis lesion detection in brain MRI by FLAIR thresholding. ( 0,821785324146347 )
Comput Math Methods Med - Esophagus segmentation from 3D CT data using skeleton prior-based graph cut. ( 0,821325598364757 )
Int J Comput Assist Radiol Surg - Automated liver lesion detection in CT images based on multi-level geometric features. ( 0,820070849778691 )
Artif Intell Med - A segmentation framework for abdominal organs from CT scans. ( 0,819555023140391 )
Int J Comput Assist Radiol Surg - A 3D active model framework for segmentation of proximal femur in MR images. ( 0,817362565512868 )
Comput Math Methods Med - A new multistage medical segmentation method based on superpixel and fuzzy clustering. ( 0,816106877627945 )
Comput Methods Programs Biomed - Image registration and atlas-based segmentation of cardiac outflow velocity profiles. ( 0,815929970276611 )
Med Biol Eng Comput - Multiplane spectroscopic whole-body photoacoustic imaging of small animals in vivo. ( 0,815772429220828 )
Med Biol Eng Comput - Automatic detection and segmentation of bovine corpora lutea in ultrasonographic ovarian images using genetic programming and rotation invariant local binary patterns. ( 0,815493311623092 )
Med Biol Eng Comput - Detection of the intima and media layer thickness of ultrasound common carotid artery image using efficient active contour segmentation technique. ( 0,812168006895458 )
IEEE Trans Image Process - 3D superalloy grain segmentation using a multichannel edge-weighted centroidal Voronoi tessellation algorithm. ( 0,808652536043225 )
Comput. Biol. Med. - A review on segmentation of positron emission tomography images. ( 0,807591549957233 )
Comput Methods Programs Biomed - Enhancing classification accuracy utilizing globules and dots features in digital dermoscopy. ( 0,805456780008631 )
J Med Syst - Automated bleeding detection in capsule endoscopy videos using statistical features and region growing. ( 0,805316181266302 )
Int J Comput Assist Radiol Surg - Local noise estimation in low-dose chest CT images. ( 0,804943720262829 )
Int J Comput Assist Radiol Surg - A computerized MRI biomarker quantification scheme for a canine model of Duchenne muscular dystrophy. ( 0,80453145023317 )
Int J Comput Assist Radiol Surg - Brain tumor detection and segmentation in a CRF (conditional random fields) framework with pixel-pairwise affinity and superpixel-level features. ( 0,804157205787224 )
J Med Syst - Brain MR image segmentation with spatial constrained K-mean algorithm and dual-tree complex wavelet transform. ( 0,803916978875318 )
Int J Comput Assist Radiol Surg - Left ventricular myocardium segmentation on delayed phase of multi-detector row computed tomography. ( 0,802691799787565 )
IEEE Trans Image Process - Automatic craniofacial structure detection on cephalometric images. ( 0,801528671604246 )
Int J Comput Assist Radiol Surg - 3D ultrasound centerline tracking of abdominal vessels for?endovascular navigation. ( 0,801084093906653 )
Comput. Biol. Med. - Estimating contrast agent motion from ultrasound images using an anisotropic diffusion-based optical flow technique. ( 0,799843682706411 )
IEEE Trans Image Process - Adaptive image registration via hierarchical Voronoi subdivision. ( 0,799435688972352 )
IEEE J Biomed Health Inform - Accurate segmentation of partially overlapping cervical cells based on dynamic sparse contour searching and GVF snake model. ( 0,796868894886579 )
J Digit Imaging - Anatomically anchored template-based level set segmentation: application to quadriceps muscles in MR images from the Osteoarthritis Initiative. ( 0,795768883241735 )
Methods Inf Med - A fast, automatic segmentation algorithm for locating and delineating touching cell boundaries in imaged histopathology. ( 0,794170483728796 )
Comput Methods Programs Biomed - Carotid artery image segmentation using modified spatial fuzzy c-means and ensemble clustering. ( 0,793302637243232 )
IEEE Trans Image Process - Segmentation of intracranial vessels and aneurysms in phase contrast magnetic resonance angiography using multirange filters and local variances. ( 0,791798968218524 )
IEEE Trans Pattern Anal Mach Intell - Paired Regions for Shadow Detection and Removal. ( 0,789380079445206 )
Comput Math Methods Med - Retrieval of brain tumors with region-specific bag-of-visual-words representations in contrast-enhanced MRI images. ( 0,786846692085993 )
Comput Methods Programs Biomed - Jaw tissues segmentation in dental 3D CT images using fuzzy-connectedness and morphological processing. ( 0,786382820984001 )
Comput Methods Programs Biomed - A fast seed detection using local geometrical feature for automatic tracking of coronary arteries in CTA. ( 0,786051143113653 )
Int J Comput Assist Radiol Surg - A two-stage rule-constrained seedless region growing approach for mandibular body segmentation in MRI. ( 0,785910581778573 )
IEEE J Biomed Health Inform - A comparison of US- versus MR-based 3-D Prostate Shapes Using Radial Basis Function Interpolation and Statistical Shape Models. ( 0,785732187961209 )
Comput Math Methods Med - Multimodal brain-tumor segmentation based on Dirichlet process mixture model with anisotropic diffusion and Markov random field prior. ( 0,785008013232085 )
Int J Comput Assist Radiol Surg - Ameliorating slice gaps in multislice magnetic resonance images: an interpolation scheme. ( 0,784665270796465 )
Comput. Biol. Med. - Gallbladder shape extraction from ultrasound images using active contour models. ( 0,783639479242854 )
Methods Inf Med - ML segmentation strategies for object interference compensation in FDG-PET lesion quantification. ( 0,783127611806448 )
Int J Neural Syst - Self-supervised MRI tissue segmentation by discriminative clustering. ( 0,782495831730804 )
J Med Syst - Computer assisted diagnostic system in tumor radiography. ( 0,78217626373921 )
Int J Comput Assist Radiol Surg - Segmentation of radiographic images under topological constraints: application to the femur. ( 0,780644814620835 )
Int J Comput Assist Radiol Surg - Delineation of blood vessels in pediatric retinal images using decision trees-based ensemble classification. ( 0,780608128634821 )
Comput. Biol. Med. - Optic disc segmentation using the sliding band filter. ( 0,780415552540836 )
Int J Comput Assist Radiol Surg - A cost-sensitive extension of AdaBoost with markov random field priors for automated segmentation of breast tumors in ultrasonic images. ( 0,77973585370903 )
Comput Methods Programs Biomed - Automatic segmentation of human facial tissue by MRI-CT fusion: a feasibility study. ( 0,779115263183909 )
Comput Methods Programs Biomed - Automatic selection of arterial input function on dynamic contrast-enhanced MR images. ( 0,778883696155024 )
Methods Inf Med - A statistical cerebroarterial atlas derived from 700 MRA datasets. ( 0,778689621109881 )
IEEE J Biomed Health Inform - Adaptive shape prior constrained level sets for bladder MR image segmentation. ( 0,775752131216516 )