Curr Comput Aided Drug Des - Recent Progress on Computer-Aided Inhibitor Design of H5N1 Influenza A Virus.

Tópicos

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{ detect(2391) sensit(1101) algorithm(908) }

Resumo

Design of novel H5N1 inhibitors is currently a research topic of vital importance owing to both a recent pandemic threat by the worldwide spread of H5N1 avian influenza and the high resistance of H5N1 virus to the most widely used commercial drug, oseltamivir-OTV (Tamiflu). There has been much progress in this field recently. This review covers recent work on bioinformatics studies, structure based design, computer modeling and molecular dynamics simulations.

Resumo Limpo

design novel hn inhibitor current research topic vital import owe recent pandem threat worldwid spread hn avian influenza high resist hn virus wide use commerci drug oseltamivirotv tamiflu much progress field recent review cover recent work bioinformat studi structur base design comput model molecular dynam simul

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