Curr Protoc Bioinformatics - Using the structure-function linkage database to characterize functional domains in enzymes.

Tópicos

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{ inform(2794) health(2639) internet(1427) }
{ compound(1573) activ(1297) structur(1058) }
{ model(3480) simul(1196) paramet(876) }
{ bind(1733) structur(1185) ligand(1036) }
{ state(1844) use(1261) util(961) }
{ data(1737) use(1416) pattern(1282) }
{ featur(3375) classif(2383) classifi(1994) }
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{ featur(1941) imag(1645) propos(1176) }
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{ model(2656) set(1616) predict(1553) }
{ age(1611) year(1155) adult(843) }
{ medic(1828) order(1363) alert(1069) }
{ signal(2180) analysi(812) frequenc(800) }
{ cost(1906) reduc(1198) effect(832) }
{ group(2977) signific(1463) compar(1072) }
{ sampl(1606) size(1419) use(1276) }
{ gene(2352) biolog(1181) express(1162) }
{ data(3008) multipl(1320) sourc(1022) }
{ first(2504) two(1366) second(1323) }
{ intervent(3218) particip(2042) group(1664) }
{ activ(1138) subject(705) human(624) }
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{ patient(1821) servic(1111) care(1106) }
{ use(2086) technolog(871) perceiv(783) }
{ can(981) present(881) function(850) }
{ health(1844) social(1437) communiti(874) }
{ structur(1116) can(940) graph(676) }
{ use(976) code(926) identifi(902) }
{ use(1733) differ(960) four(931) }
{ drug(1928) target(777) effect(648) }
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{ detect(2391) sensit(1101) algorithm(908) }

Resumo

The Structure-Function Linkage Database (SFLD; http://sfld.rbvi.ucsf.edu/) is a Web-accessible database designed to link enzyme sequence, structure, and functional information. This unit describes the protocols by which a user may query the database to predict the function of uncharacterized enzymes and to correct misannotated functional assignments. The information in this unit is especially useful in helping a user discriminate functional capabilities of a sequence that is only distantly related to characterized sequences in publicly available databases. ? 2014 by John Wiley & Sons, Inc.

Resumo Limpo

structurefunct linkag databas sfld httpsfldrbviucsfedu webaccess databas design link enzym sequenc structur function inform unit describ protocol user may queri databas predict function uncharacter enzym correct misannot function assign inform unit especi use help user discrimin function capabl sequenc distant relat character sequenc public avail databas john wiley son inc

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