IEEE J Biomed Health Inform - Automated recovery of the center of rotation in optical projection tomography in the presence of scattering.

Tópicos

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Resumo

Finding the center of rotation is an essential step for accurate three-dimensional reconstruction in optical projection tomography (OPT). Unfortunately current methods are not convenient since they require either prior scanning of a reference phantom, small structures of high intensity existing in the specimen, or active participation during the centering procedure. To solve these problems this paper proposes a fast and automatic center of rotation search method making use of parallel programming in graphics processing units (GPUs). Our method is based on a two step search approach making use only of those sections of the image with high signal to noise ratio. We have tested this method both in non-scattering ex vivo samples and in in vivo specimens with a considerable contribution of scattering such as Drosophila melanogaster pupae, recovering in all cases the center of rotation with a precision 1/4 pixel or less.

Resumo Limpo

find center rotat essenti step accur threedimension reconstruct optic project tomographi opt unfortun current method conveni sinc requir either prior scan refer phantom small structur high intens exist specimen activ particip center procedur solv problem paper propos fast automat center rotat search method make use parallel program graphic process unit gpus method base two step search approach make use section imag high signal nois ratio test method nonscatt ex vivo sampl vivo specimen consider contribut scatter drosophila melanogast pupa recov case center rotat precis pixel less

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