IEEE J Biomed Health Inform - Exploiting Semantic Web Technologies to Develop OWL-Based Clinical Practice Guideline Execution Engines.

Tópicos

{ concept(1167) ontolog(924) domain(897) }
{ medic(1828) order(1363) alert(1069) }
{ method(1219) similar(1157) match(930) }
{ howev(809) still(633) remain(590) }
{ system(1976) rule(880) can(841) }
{ cost(1906) reduc(1198) effect(832) }
{ assess(1506) score(1403) qualiti(1306) }
{ model(2656) set(1616) predict(1553) }
{ data(1714) softwar(1251) tool(1186) }
{ cancer(2502) breast(956) screen(824) }
{ intervent(3218) particip(2042) group(1664) }
{ implement(1333) system(1263) develop(1122) }
{ can(774) often(719) complex(702) }
{ treatment(1704) effect(941) patient(846) }
{ studi(1410) differ(1259) use(1210) }
{ blood(1257) pressur(1144) flow(957) }
{ result(1111) use(1088) new(759) }
{ data(1737) use(1416) pattern(1282) }
{ motion(1329) object(1292) video(1091) }
{ clinic(1479) use(1117) guidelin(835) }
{ algorithm(1844) comput(1787) effici(935) }
{ control(1307) perform(991) simul(935) }
{ model(2220) cell(1177) simul(1124) }
{ care(1570) inform(1187) nurs(1089) }
{ search(2224) databas(1162) retriev(909) }
{ case(1353) use(1143) diagnosi(1136) }
{ research(1085) discuss(1038) issu(1018) }
{ health(3367) inform(1360) care(1135) }
{ patient(2837) hospit(1953) medic(668) }
{ signal(2180) analysi(812) frequenc(800) }
{ first(2504) two(1366) second(1323) }
{ patient(1821) servic(1111) care(1106) }
{ process(1125) use(805) approach(778) }
{ model(3404) distribut(989) bayesian(671) }
{ imag(1947) propos(1133) code(1026) }
{ inform(2794) health(2639) internet(1427) }
{ measur(2081) correl(1212) valu(896) }
{ imag(1057) registr(996) error(939) }
{ bind(1733) structur(1185) ligand(1036) }
{ sequenc(1873) structur(1644) protein(1328) }
{ featur(3375) classif(2383) classifi(1994) }
{ imag(2830) propos(1344) filter(1198) }
{ network(2748) neural(1063) input(814) }
{ imag(2675) segment(2577) method(1081) }
{ patient(2315) diseas(1263) diabet(1191) }
{ take(945) account(800) differ(722) }
{ studi(2440) review(1878) systemat(933) }
{ surgeri(1148) surgic(1085) robot(1054) }
{ framework(1458) process(801) describ(734) }
{ problem(2511) optim(1539) algorithm(950) }
{ error(1145) method(1030) estim(1020) }
{ chang(1828) time(1643) increas(1301) }
{ learn(2355) train(1041) set(1003) }
{ extract(1171) text(1153) clinic(932) }
{ method(1557) propos(1049) approach(1037) }
{ design(1359) user(1324) use(1319) }
{ general(901) number(790) one(736) }
{ method(984) reconstruct(947) comput(926) }
{ featur(1941) imag(1645) propos(1176) }
{ data(3963) clinic(1234) research(1004) }
{ risk(3053) factor(974) diseas(938) }
{ perform(999) metric(946) measur(919) }
{ system(1050) medic(1026) inform(1018) }
{ import(1318) role(1303) understand(862) }
{ model(2341) predict(2261) use(1141) }
{ visual(1396) interact(850) tool(830) }
{ compound(1573) activ(1297) structur(1058) }
{ perform(1367) use(1326) method(1137) }
{ studi(1119) effect(1106) posit(819) }
{ spatial(1525) area(1432) region(1030) }
{ record(1888) medic(1808) patient(1693) }
{ model(3480) simul(1196) paramet(876) }
{ monitor(1329) mobil(1314) devic(1160) }
{ ehr(2073) health(1662) electron(1139) }
{ state(1844) use(1261) util(961) }
{ research(1218) medic(880) student(794) }
{ data(2317) use(1299) case(1017) }
{ age(1611) year(1155) adult(843) }
{ group(2977) signific(1463) compar(1072) }
{ sampl(1606) size(1419) use(1276) }
{ gene(2352) biolog(1181) express(1162) }
{ data(3008) multipl(1320) sourc(1022) }
{ activ(1138) subject(705) human(624) }
{ time(1939) patient(1703) rate(768) }
{ use(2086) technolog(871) perceiv(783) }
{ can(981) present(881) function(850) }
{ analysi(2126) use(1163) compon(1037) }
{ health(1844) social(1437) communiti(874) }
{ structur(1116) can(940) graph(676) }
{ high(1669) rate(1365) level(1280) }
{ use(976) code(926) identifi(902) }
{ use(1733) differ(960) four(931) }
{ drug(1928) target(777) effect(648) }
{ survey(1388) particip(1329) question(1065) }
{ estim(2440) model(1874) function(577) }
{ decis(3086) make(1611) patient(1517) }
{ activ(1452) weight(1219) physic(1104) }
{ method(1969) cluster(1462) data(1082) }
{ method(2212) result(1239) propos(1039) }
{ detect(2391) sensit(1101) algorithm(908) }

Resumo

Computerizing paper-based CPG and then executing them can provide evidence-informed decision support to physicians at the point of care. Semantic web technologies especially Web Ontology Language (OWL) ontologies have been profusely used to represent computerized CPG. Using semantic web reasoning capabilities to execute OWL based computerized CPG unties them from a specific custom-built CPG execution engine and increases their shareability as any OWL reasoner and triple store can be utilized for CPG execution. However, existing semantic web reasoning based CPG execution engines suffer from lack of ability to execute CPG with high levels of expressivity, high cognitive load of computerization of paper-based CPG and updating their computerized versions. In order to address these limitations, we have developed three CPG execution engines based on OWL 1 DL, OWL 2 DL and OWL 2 DL + Semantic Web Rule Language (SWRL). OWL 1 DL serves as the base execution engine capable of executing a wide range of CPG constructs, however for executing highly complex CPG the OWL 2 DL and OWL 2 DL + SWRL offer additional executional capabilities. We evaluated the technical performance and medical correctness of our execution engines using a range of CPG. Technical evaluations show the efficiency of our CPG execution engines in terms of CPU time and validity of the generated recommendation in comparison to existing CPG execution engines. Medical evaluations by domain experts show the validity of the CPG-mediated therapy plans in terms of relevance, safety, and ordering for a wide range of patient scenarios.

Resumo Limpo

computer paperbas cpg execut can provid evidenceinform decis support physician point care semant web technolog especi web ontolog languag owl ontolog profus use repres computer cpg use semant web reason capabl execut owl base computer cpg unti specif custombuilt cpg execut engin increas shareabl owl reason tripl store can util cpg execut howev exist semant web reason base cpg execut engin suffer lack abil execut cpg high level express high cognit load computer paperbas cpg updat computer version order address limit develop three cpg execut engin base owl dl owl dl owl dl semant web rule languag swrl owl dl serv base execut engin capabl execut wide rang cpg construct howev execut high complex cpg owl dl owl dl swrl offer addit execut capabl evalu technic perform medic correct execut engin use rang cpg technic evalu show effici cpg execut engin term cpu time valid generat recommend comparison exist cpg execut engin medic evalu domain expert show valid cpgmediat therapi plan term relev safeti order wide rang patient scenario

Resumos Similares

Methods Inf Med - An evolutionary approach to realism-based adverse event representations. ( 0,881730961162441 )
J Biomed Inform - Development and evaluation of an ontology for guiding appropriate antibiotic prescribing. ( 0,87703030374458 )
J Biomed Inform - Integrating reasoning and clinical archetypes using OWL ontologies and SWRL rules. ( 0,868236522150708 )
J Am Med Inform Assoc - Life sciences domain analysis model. ( 0,864372080325329 )
J Biomed Inform - A federated semantic metadata registry framework for enabling interoperability across clinical research and care domains. ( 0,863909514656893 )
Methods Inf Med - An eligibility criteria query language for heterogeneous data warehouses. ( 0,843615294188281 )
BMC Med Inform Decis Mak - Querying phenotype-genotype relationships on patient datasets using semantic web technology: the example of Cerebrotendinous xanthomatosis. ( 0,839354099960228 )
AMIA Annu Symp Proc - Modeling and executing electronic health records driven phenotyping algorithms using the NQF Quality Data Model and JBoss? Drools Engine. ( 0,838848834064762 )
J Biomed Inform - Natural Language Processing methods and systems for biomedical ontology learning. ( 0,837578560153547 )
Artif Intell Med - The Foundational Model of Anatomy in OWL 2 and its use. ( 0,837417559771565 )
J Biomed Inform - Reuse of termino-ontological resources and text corpora for building a multilingual domain ontology: an application to Alzheimer's disease. ( 0,835209514295187 )
Appl Clin Inform - Ontology content patterns as bridge for the semantic representation of clinical information. ( 0,834489929156982 )
J Am Med Inform Assoc - A semantic-web oriented representation of the clinical element model for secondary use of electronic health records data. ( 0,829806854078173 )
AMIA Annu Symp Proc - Evaluation of RxNorm for Representing Ambulatory Prescriptions. ( 0,828980555234112 )
AMIA Annu Symp Proc - Deriving an abstraction network to support quality assurance in OCRe. ( 0,827108303815129 )
Int J Med Inform - A modified Delphi translation strategy and challenges of International Classification for Nursing Practice (ICNP?). ( 0,826401682814998 )
Methods Inf Med - Construction of an interface terminology on SNOMED CT. Generic approach and its application in intensive care. ( 0,825030755163114 )
J Biomed Inform - Enabling international adoption of LOINC through translation. ( 0,822737883428557 )
AMIA Annu Symp Proc - Auditing SNOMED Integration into the UMLS for Duplicate Concepts. ( 0,8163582517863 )
Methods Inf Med - Evaluation of the content coverage of SNOMED CT representing ICNP seven-axis version 1 concepts. ( 0,812135338763189 )
AMIA Annu Symp Proc - Standardized mapping of nursing assessments across 59 U.S. military treatment facilities. ( 0,809944733024118 )
BMC Med Inform Decis Mak - Retrospective checking of compliance with practice guidelines for acute stroke care: a novel experiment using openEHR's Guideline Definition Language. ( 0,809409184015665 )
J Biomed Inform - An ontology-based measure to compute semantic similarity in biomedicine. ( 0,808804369914546 )
J Biomed Inform - TRAK ontology: defining standard care for the rehabilitation of knee conditions. ( 0,807071249961757 )
J Am Med Inform Assoc - Scalable quality assurance for large SNOMED CT hierarchies using subject-based subtaxonomies. ( 0,802360792035154 )
BMC Med Inform Decis Mak - Translating the Foundational Model of Anatomy into French using knowledge-based and lexical methods. ( 0,798990909502586 )
AMIA Annu Symp Proc - Fostering Multilinguality in the UMLS: A Computational Approach to Terminology Expansion for Multiple Languages. ( 0,798310765217864 )
Telemed J E Health - Construction of a clinical decision support system for undergoing surgery based on domain ontology and rules reasoning. ( 0,795469621254432 )
Inform Health Soc Care - Semantics-driven modelling of user preferences for information retrieval in the biomedical domain. ( 0,790257602730575 )
J Biomed Inform - A query integrator and manager for the query web. ( 0,788982086751135 )
J Biomed Inform - Semantic mappings and locality of nursing diagnostic concepts in UMLS. ( 0,7863049208017 )
J Biomed Inform - Cross-product extensions of the Gene Ontology. ( 0,784074212874682 )
Int J Med Inform - Semantic similarity-based alignment between clinical archetypes and SNOMED CT: an application to observations. ( 0,783922067197826 )
AMIA Annu Symp Proc - Psychological assessment instruments: a coverage analysis using SNOMED CT, LOINC and QS terminology. ( 0,78038031727837 )
J Am Med Inform Assoc - Applying knowledge-anchored hypothesis discovery methods to advance clinical and translational research: the OAMiner project. ( 0,78005013070496 )
J Biomed Inform - A framework for unifying ontology-based semantic similarity measures: a study in the biomedical domain. ( 0,77955487055614 )
J Biomed Inform - Enabling semantic similarity estimation across multiple ontologies: an evaluation in the biomedical domain. ( 0,779187047273939 )
J Biomed Inform - Validating the semantics of a medical iconic language using ontological reasoning. ( 0,777891982928222 )
J Biomed Inform - Hematopoietic cell types: prototype for a revised cell ontology. ( 0,776661630359726 )
J Biomed Inform - Using LOINC to link 10 terminology standards to one unified standard in a specialized domain. ( 0,775487135177325 )
AMIA Annu Symp Proc - Modeling patient safety incidents knowledge with the Categorial Structure method. ( 0,774338492587775 )
J. Med. Internet Res. - Development of an obesity management ontology based on the nursing process for the mobile-device domain. ( 0,774264759399589 )
Appl Clin Inform - An empiric analysis of omaha system targets. ( 0,773773420172038 )
AMIA Annu Symp Proc - Assessing the performance of LOINC? and RadLex for coverage of CT scans across three sites in a health information exchange. ( 0,771553957316589 )
Comput Methods Programs Biomed - Application of probabilistic and fuzzy cognitive approaches in semantic web framework for medical decision support. ( 0,771155762635915 )
Comput. Biol. Med. - An ontology of cancer therapies supporting interoperability and data consistency in EPRs. ( 0,770229037755293 )
J Biomed Inform - BOAT: automatic alignment of biomedical ontologies using term informativeness and candidate selection. ( 0,769639868260805 )
J Am Med Inform Assoc - Approaching semantic interoperability in Health Level Seven. ( 0,765619708178475 )
Artif Intell Med - Intra-axiom redundancies in SNOMED CT. ( 0,761027067210783 )
AMIA Annu Symp Proc - Metonymies in medical terminologies. A SNOMED CT case study. ( 0,760235114955589 )
J Biomed Inform - Cross-domain targeted ontology subsets for annotation: the case of SNOMED CORE and RxNorm. ( 0,757072665795445 )
J Biomed Inform - A methodology for extending domain coverage in SemRep. ( 0,756482780004358 )
BMC Med Inform Decis Mak - Determining correspondences between high-frequency MedDRA concepts and SNOMED: a case study. ( 0,754826277771557 )
J Biomed Inform - Acquisition and evaluation of verb subcategorization resources for biomedicine. ( 0,754324450860866 )
J Biomed Inform - vSPARQL: a view definition language for the semantic web. ( 0,752593722236994 )
J Biomed Inform - Deriving a probabilistic syntacto-semantic grammar for biomedicine based on domain-specific terminologies. ( 0,752205792226643 )
J Biomed Inform - Translating standards into practice - one Semantic Web API for Gene Expression. ( 0,74748456269755 )
Methods Inf Med - Biomedical ontologies: toward scientific debate. ( 0,747414455203273 )
J Biomed Inform - Terminology representation guidelines for biomedical ontologies in the semantic web notations. ( 0,745527256724805 )
J Chem Inf Model - Setting the record straight: the origin of the pharmacophore concept. ( 0,74335485127974 )
AMIA Annu Symp Proc - Adapting a Clinical Data Repository to ICD-10-CM through the use of a Terminology Repository. ( 0,742486007528527 )
J Med Syst - Automated mapping of clinical terms into SNOMED-CT. An application to codify procedures in pathology. ( 0,741548470544129 )
J Biomed Inform - Formalizing MedDRA to support semantic reasoning on adverse drug reaction terms. ( 0,74070493398273 )
J Med Syst - Time-related patient data retrieval for the case studies from the pharmacogenomics research network. ( 0,739792221009394 )
J Am Med Inform Assoc - Evaluating standard terminologies for encoding allergy information. ( 0,739789850220604 )
Methods Inf Med - Putting biomedical ontologies to work. ( 0,739604094246293 )
Int J Med Inform - Using ontologies for structuring organizational knowledge in Home Care assistance. ( 0,739362641237587 )
J Integr Bioinform - An ontology for description of drug discovery investigations. ( 0,738636381938284 )
AMIA Annu Symp Proc - Applying Evolutionary Terminology Auditing to SNOMED CT. ( 0,736085258031876 )
AMIA Annu Symp Proc - A family-based framework for supporting quality assurance of biomedical ontologies in BioPortal. ( 0,735478082519041 )
Brief. Bioinformatics - Semantic Web meets Integrative Biology: a survey. ( 0,734561782400287 )
Comput Methods Programs Biomed - Searching biosignal databases by content and context: Research Oriented Integration System for ECG Signals (ROISES). ( 0,734539476171109 )
IEEE Trans Image Process - Structure-preserving sparse decomposition for facial expression analysis. ( 0,733194693968358 )
AMIA Annu Symp Proc - Reasoning based quality assurance of medical ontologies: a case study. ( 0,732182453783758 )
J Biomed Inform - OntoVIP: an ontology for the annotation of object models used for medical image simulation. ( 0,730042965420204 )
AMIA Annu Symp Proc - Representation of nursing terminologies in UMLS. ( 0,729872342084927 )
Methods Inf Med - Toward a view-oriented approach for aligning RDF-based biomedical repositories. ( 0,729038878031242 )
J Am Med Inform Assoc - Evaluation of the NCPDP Structured and Codified Sig Format for e-prescriptions. ( 0,727992488748474 )
AMIA Annu Symp Proc - Quality assurance in LOINC using Description Logic. ( 0,724637037284118 )
AMIA Annu Symp Proc - Towards the creation of a visual ontology of biomedical imaging entities. ( 0,724366267906144 )
Perspect Health Inf Manag - Personal health records: is rapid adoption hindering interoperability? ( 0,724278977029679 )
J Biomed Inform - A network-theoretic approach for decompositional translation across Open Biological Ontologies. ( 0,724061832911028 )
AMIA Annu Symp Proc - Looking for Anemia (and Other Disorders) in SNOMED CT: Comparison of Three Approaches and Practical Implications. ( 0,723189136251863 )
J Am Med Inform Assoc - Using the wisdom of the crowds to find critical errors in biomedical ontologies: a study of SNOMED CT. ( 0,722689122125277 )
Artif Intell Med - A four stage approach for ontology-based health information system design. ( 0,718208811924461 )
J Biomed Inform - NanoParticle Ontology for cancer nanotechnology research. ( 0,715620806300874 )
J Biomed Inform - Abstraction of complex concepts with a refined partial-area taxonomy of SNOMED. ( 0,712556751235998 )
J Biomed Inform - OWL-based reasoning methods for validating archetypes. ( 0,712198096171044 )
J Biomed Inform - COnto-Diff: generation of complex evolution mappings for life science ontologies. ( 0,710780863607877 )
AMIA Annu Symp Proc - Clinical information system services and capabilities desired for scalable, standards-based, service-oriented decision support: consensus assessment of the Health Level 7 clinical decision support Work Group. ( 0,710476863325722 )
AMIA Annu Symp Proc - Identifying Granularity Differences between Large Biomedical Ontologies through Rules. ( 0,706432804456907 )
J Am Med Inform Assoc - An adaptable architecture for patient cohort identification from diverse data sources. ( 0,706422662911911 )
J Biomed Inform - Semantic mapping to simplify deployment of HL7 v3 Clinical Document Architecture. ( 0,70583744376993 )
IEEE J Biomed Health Inform - Providing semantic interoperability between clinical care and clinical research domains. ( 0,705423617242053 )
J Biomed Inform - Understanding semantic mapping evolution by observing changes in biomedical ontologies. ( 0,705216002851372 )
J Am Med Inform Assoc - The National Center for Biomedical Ontology. ( 0,704246182527906 )
J Am Med Inform Assoc - A unified structural/terminological interoperability framework based on LexEVS: application to TRANSFoRm. ( 0,702239871619554 )
Artif Intell Med - Cue-based assertion classification for Swedish clinical text--developing a lexicon for pyConTextSwe. ( 0,699953291727749 )
J Am Med Inform Assoc - Mapping clinical phenotype data elements to standardized metadata repositories and controlled terminologies: the eMERGE Network experience. ( 0,696601307699023 )
Comput Methods Programs Biomed - BiOSS: A system for biomedical ontology selection. ( 0,695998626811992 )