IEEE Trans Image Process - Incorporating anatomical side information into PET reconstruction using nonlocal regularization.

Tópicos

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Resumo

With the introduction of combined positron emission tomography (PET)/computed tomography (CT) or PET/magnetic resonance imaging (MRI) scanners, there is an increasing emphasis on reconstructing PET images with the aid of the anatomical side information obtained from X-ray CT or MRI scanners. In this paper, we propose a new approach to incorporating prior anatomical information into PET reconstruction using the nonlocal regularization method. The nonlocal regularizer developed for this application is designed to selectively consider the anatomical information only when it is reliable. As our proposed nonlocal regularization method does not directly use anatomical edges or boundaries which are often used in conventional methods, it is not only free from additional processes to extract anatomical boundaries or segmented regions, but also more robust to the signal mismatch problem that is caused by the indirect relationship between the PET image and the anatomical image. We perform simulations with digital phantoms. According to our experimental results, compared to the conventional method based on the traditional local regularization method, our nonlocal regularization method performs well even with the imperfect prior anatomical information or in the presence of signal mismatch between the PET image and the anatomical image.

Resumo Limpo

introduct combin positron emiss tomographi petcomput tomographi ct petmagnet reson imag mri scanner increas emphasi reconstruct pet imag aid anatom side inform obtain xray ct mri scanner paper propos new approach incorpor prior anatom inform pet reconstruct use nonloc regular method nonloc regular develop applic design select consid anatom inform reliabl propos nonloc regular method direct use anatom edg boundari often use convent method free addit process extract anatom boundari segment region also robust signal mismatch problem caus indirect relationship pet imag anatom imag perform simul digit phantom accord experiment result compar convent method base tradit local regular method nonloc regular method perform well even imperfect prior anatom inform presenc signal mismatch pet imag anatom imag

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