AMIA Annu Symp Proc - Simulation Analysis Platform (SnAP): a tool for evaluation of public health surveillance and disease control strategies.

Tópicos

{ model(3480) simul(1196) paramet(876) }
{ data(1714) softwar(1251) tool(1186) }
{ data(2317) use(1299) case(1017) }
{ algorithm(1844) comput(1787) effici(935) }
{ analysi(2126) use(1163) compon(1037) }
{ control(1307) perform(991) simul(935) }
{ howev(809) still(633) remain(590) }
{ studi(1410) differ(1259) use(1210) }
{ implement(1333) system(1263) develop(1122) }
{ method(1969) cluster(1462) data(1082) }
{ inform(2794) health(2639) internet(1427) }
{ framework(1458) process(801) describ(734) }
{ extract(1171) text(1153) clinic(932) }
{ featur(1941) imag(1645) propos(1176) }
{ research(1085) discuss(1038) issu(1018) }
{ import(1318) role(1303) understand(862) }
{ age(1611) year(1155) adult(843) }
{ model(3404) distribut(989) bayesian(671) }
{ imag(1057) registr(996) error(939) }
{ take(945) account(800) differ(722) }
{ studi(2440) review(1878) systemat(933) }
{ treatment(1704) effect(941) patient(846) }
{ clinic(1479) use(1117) guidelin(835) }
{ compound(1573) activ(1297) structur(1058) }
{ perform(1367) use(1326) method(1137) }
{ blood(1257) pressur(1144) flow(957) }
{ ehr(2073) health(1662) electron(1139) }
{ can(981) present(881) function(850) }
{ use(1733) differ(960) four(931) }
{ method(2212) result(1239) propos(1039) }
{ can(774) often(719) complex(702) }
{ imag(1947) propos(1133) code(1026) }
{ data(1737) use(1416) pattern(1282) }
{ system(1976) rule(880) can(841) }
{ measur(2081) correl(1212) valu(896) }
{ bind(1733) structur(1185) ligand(1036) }
{ sequenc(1873) structur(1644) protein(1328) }
{ method(1219) similar(1157) match(930) }
{ featur(3375) classif(2383) classifi(1994) }
{ imag(2830) propos(1344) filter(1198) }
{ network(2748) neural(1063) input(814) }
{ imag(2675) segment(2577) method(1081) }
{ patient(2315) diseas(1263) diabet(1191) }
{ motion(1329) object(1292) video(1091) }
{ assess(1506) score(1403) qualiti(1306) }
{ surgeri(1148) surgic(1085) robot(1054) }
{ problem(2511) optim(1539) algorithm(950) }
{ error(1145) method(1030) estim(1020) }
{ chang(1828) time(1643) increas(1301) }
{ learn(2355) train(1041) set(1003) }
{ concept(1167) ontolog(924) domain(897) }
{ method(1557) propos(1049) approach(1037) }
{ design(1359) user(1324) use(1319) }
{ model(2220) cell(1177) simul(1124) }
{ care(1570) inform(1187) nurs(1089) }
{ general(901) number(790) one(736) }
{ method(984) reconstruct(947) comput(926) }
{ search(2224) databas(1162) retriev(909) }
{ case(1353) use(1143) diagnosi(1136) }
{ data(3963) clinic(1234) research(1004) }
{ risk(3053) factor(974) diseas(938) }
{ perform(999) metric(946) measur(919) }
{ system(1050) medic(1026) inform(1018) }
{ model(2341) predict(2261) use(1141) }
{ visual(1396) interact(850) tool(830) }
{ studi(1119) effect(1106) posit(819) }
{ spatial(1525) area(1432) region(1030) }
{ record(1888) medic(1808) patient(1693) }
{ health(3367) inform(1360) care(1135) }
{ monitor(1329) mobil(1314) devic(1160) }
{ state(1844) use(1261) util(961) }
{ research(1218) medic(880) student(794) }
{ patient(2837) hospit(1953) medic(668) }
{ model(2656) set(1616) predict(1553) }
{ medic(1828) order(1363) alert(1069) }
{ signal(2180) analysi(812) frequenc(800) }
{ cost(1906) reduc(1198) effect(832) }
{ group(2977) signific(1463) compar(1072) }
{ sampl(1606) size(1419) use(1276) }
{ gene(2352) biolog(1181) express(1162) }
{ data(3008) multipl(1320) sourc(1022) }
{ first(2504) two(1366) second(1323) }
{ intervent(3218) particip(2042) group(1664) }
{ activ(1138) subject(705) human(624) }
{ time(1939) patient(1703) rate(768) }
{ patient(1821) servic(1111) care(1106) }
{ use(2086) technolog(871) perceiv(783) }
{ health(1844) social(1437) communiti(874) }
{ structur(1116) can(940) graph(676) }
{ high(1669) rate(1365) level(1280) }
{ cancer(2502) breast(956) screen(824) }
{ use(976) code(926) identifi(902) }
{ drug(1928) target(777) effect(648) }
{ result(1111) use(1088) new(759) }
{ survey(1388) particip(1329) question(1065) }
{ estim(2440) model(1874) function(577) }
{ decis(3086) make(1611) patient(1517) }
{ process(1125) use(805) approach(778) }
{ activ(1452) weight(1219) physic(1104) }
{ detect(2391) sensit(1101) algorithm(908) }

Resumo

Increasingly, researchers use simulation to generate realistic population health data to evaluate surveillance and disease control methods. This evaluation approach is attractive because real data are often not available to describe the full range of population health trajectories that may occur. Simulation models, especially agent-based models, tend to have many parameters and it is often difficult for researchers to evaluate the effect of the multiple parameter values on model outcomes. In this paper, we describe Simulation Analysis Platform (SnAP) - a software infrastructure for automatically deploying and analyzing multiple runs of a simulation model in a manner that efficiently explores the influence of parameter uncertainty and random error on model outcomes. SnAP is designed to be efficient, scalable, extensible, and portable. We describe the design decisions taken to meet these requirements, present the design of the platform, and describe results from an example application of SnAP.

Resumo Limpo

increas research use simul generat realist popul health data evalu surveil diseas control method evalu approach attract real data often avail describ full rang popul health trajectori may occur simul model especi agentbas model tend mani paramet often difficult research evalu effect multipl paramet valu model outcom paper describ simul analysi platform snap softwar infrastructur automat deploy analyz multipl run simul model manner effici explor influenc paramet uncertainti random error model outcom snap design effici scalabl extens portabl describ design decis taken meet requir present design platform describ result exampl applic snap

Resumos Similares

Comput Methods Programs Biomed - Facilitating pharmacometric workflow with the metrumrg package for R. ( 0,777779756214234 )
Comput Math Methods Med - Spongiosa primary development: a biochemical hypothesis by Turing patterns formations. ( 0,751173708920188 )
Comput Math Methods Med - ModeLang: a new approach for experts-friendly viral infections modeling. ( 0,69142638281973 )
Comput Math Methods Med - Uncertainty quantification in simulations of epidemics using polynomial chaos. ( 0,690719499933336 )
Comput Methods Programs Biomed - Simulating and analysing infectious disease data in a heterogeneous population with migration. ( 0,689601461756236 )
Brief. Bioinformatics - Choosing appropriate models for protein-protein interaction networks: a comparison study. ( 0,687220241858085 )
Comput Methods Programs Biomed - Numerical framework to model temporally resolved multi-stage dynamic systems. ( 0,681825354004805 )
Comput Math Methods Med - Analytical solutions for the mathematical model describing the formation of liver zones via Adomian's method. ( 0,675975353260607 )
Comput Math Methods Med - Computational modeling of microabscess formation. ( 0,672525936096568 )
Comput Math Methods Med - Numerical stability of partitioned approach in fluid-structure interaction for a deformable thin-walled vessel. ( 0,672453773309368 )
Comput Methods Programs Biomed - Graphical simulation environments for modelling and simulation of integrative physiology. ( 0,667990833229237 )
Comput Math Methods Med - Modeling innate immune response to early Mycobacterium infection. ( 0,665712451127522 )
Comput Math Methods Med - Dynamics analysis and simulation of a modified HIV infection model with a saturated infection rate. ( 0,664358867601533 )
J. Comput. Biol. - An overview of population genetic data simulation. ( 0,658124374089319 )
Comput Biol Chem - An efficient nonlinear finite-difference approach in the computational modeling of the dynamics of a nonlinear diffusion-reaction equation in microbial ecology. ( 0,654091679220276 )
Comput. Biol. Med. - Biomechanical simulation of anterior cruciate ligament strain for sports injury prevention. ( 0,646868963687031 )
Wiley Interdiscip Rev Syst Biol Med - Influenza A virus infection kinetics: quantitative data and models. ( 0,646002110815346 )
Comput. Biol. Med. - ODE/PDE analysis of corneal curvature. ( 0,640862696722295 )
Comput Biol Chem - A stochastic evolution model for residue Insertion-Deletion Independent from Substitution. ( 0,640108038089359 )
Comput Math Methods Med - Modeling schistosomiasis and HIV/AIDS codynamics. ( 0,63689387092113 )
Comput Math Methods Med - Numerical solutions for a model of tissue invasion and migration of tumour cells. ( 0,634820213624307 )
J Integr Bioinform - An advanced environment for hybrid modeling of biological systems based on modelica. ( 0,634455801527861 )
Comput. Biol. Med. - Computing the stability of steady-state solutions of mathematical models of the electrical activity in the heart. ( 0,632135972368016 )
Comput Methods Programs Biomed - Reprint of Pharmacokinetic modelling of the anti-malarial drug artesunate and its active metabolite dihydroartemisinin. ( 0,627663036690807 )
Wiley Interdiscip Rev Syst Biol Med - A conceptual framework for computational models of Achilles tendon homeostasis. ( 0,627072051743007 )
Neural Comput - Analytical integrate-and-fire neuron models with conductance-based dynamics and realistic postsynaptic potential time course for event-driven simulation strategies. ( 0,625227619912461 )
Comput Methods Programs Biomed - Development of a computer algorithm for feedback controlled electrical nerve fiber stimulation. ( 0,624723900065313 )
J Chem Inf Model - ThermoData Engine (TDE): software implementation of the dynamic data evaluation concept. 8. Properties of material streams and solvent design. ( 0,622806592631423 )
Comput Biol Chem - Parameter sensitivity analysis of stochastic models: application to catalytic reaction networks. ( 0,622620952259126 )
Brief. Bioinformatics - High performance cellular level agent-based simulation with FLAME for the GPU. ( 0,621965723680499 )
J Chem Inf Model - Full and partial agonism of ionotropic glutamate receptors indicated by molecular dynamics simulations. ( 0,62160089131034 )
Comput Methods Programs Biomed - Functionality of the baroreceptor nerves in heart rate regulation. ( 0,620686869826024 )
Med Biol Eng Comput - CSF dynamic analysis of a predictive pulsatility-based infusion test for normal pressure hydrocephalus. ( 0,620619211235379 )
Comput Methods Programs Biomed - A Java simulator of Rescorla and Wagner's prediction error model and configural cue extensions. ( 0,620429927784328 )
Comput. Biol. Med. - epiModel: a system to build automatically systems of differential equations of compartmental type-epidemiological models. ( 0,618416863976626 )
Comput. Biol. Med. - Modelling and simulating reaction-diffusion systems using coloured Petri nets. ( 0,617461308936969 )
Comput Methods Programs Biomed - An efficient passive planar micromixer with ellipse-like micropillars for continuous mixing of human blood. ( 0,615486595886351 )
J Chem Inf Model - DockoMatic 2.0: high throughput inverse virtual screening and homology modeling. ( 0,61511909904224 )
Comput. Biol. Med. - Examples of testing global identifiability of biological and biomedical models with the DAISY software. ( 0,615002066272207 )
Comput. Biol. Med. - Modeling stroke rehabilitation processes using the Unified Modeling Language (UML). ( 0,614724784400097 )
Comput Math Methods Med - Solutions of a linearized mathematical model for capillary formation in tumor angiogenesis: an initial data perturbation approximation. ( 0,612007011970556 )
Comput Methods Programs Biomed - A model of cerebral cortex formation during fetal development using reaction-diffusion-convection equations with Turing space parameters. ( 0,610894114269319 )
J Biomed Inform - Chronic disease modeling and simulation software. ( 0,607773239407236 )
Neural Comput - Effect of phase response curve skewness on synchronization of electrically coupled neuronal oscillators. ( 0,605457576595071 )
Brief. Bioinformatics - RegScan: a GWAS tool for quick estimation of allele effects on continuous traits and their combinations. ( 0,603183040786501 )
J Chem Inf Model - ThermoData Engine (TDE): software implementation of the dynamic data evaluation concept. 9. Extensible thermodynamic constraints for pure compounds and new model developments. ( 0,602637222818631 )
J Clin Monit Comput - The standard strong ion difference, standard total titratable base, and their relationship to the Boston compensation rules and the Van Slyke equation for extracellular fluid. ( 0,601464544830382 )
Neural Comput - Computing confidence intervals for point process models. ( 0,601266157030572 )
Comput Methods Programs Biomed - Solving delay differential equations in S-ADAPT by method of steps. ( 0,601183189341567 )
Brief. Bioinformatics - Investigating biocomplexity through the agent-based paradigm. ( 0,600307884997593 )
IEEE Trans Vis Comput Graph - Paraglide: Interactive Parameter Space Partitioning for Computer Simulations. ( 0,598969215278547 )
Neural Comput - Cross-talk induces bifurcations in nonlinear models of synaptic plasticity. ( 0,597657374153376 )
Neural Comput - MOSAIC for multiple-reward environments. ( 0,596522156052806 )
J Integr Bioinform - WIBL: Workbench for Integrative Biological Learning. ( 0,594730126093935 )
Comput Math Methods Med - Global hopf bifurcation on two-delays leslie-gower predator-prey system with a prey refuge. ( 0,592342743211194 )
J Chem Inf Model - JGromacs: a Java package for analyzing protein simulations. ( 0,590192141260625 )
Comput Methods Programs Biomed - Using off-the-shelf tools for terabyte-scale waveform recording in intensive care: computer system design, database description and lessons learned. ( 0,588141659619347 )
Comput. Biol. Med. - Modeling multiple experiments using regularized optimization: A case study on bacterial glucose utilization dynamics. ( 0,584492640432228 )
Comput Methods Programs Biomed - Design of a framework for modeling, integration and simulation of physiological models. ( 0,582075974779204 )
Comput. Biol. Med. - A compartment model of alveolar-capillary oxygen diffusion with ventilation-perfusion gradient and dynamics of air transport through the respiratory tract. ( 0,581074653487351 )
J Chem Inf Model - Carbohydrate structure generalization scheme for database-driven simulation of experimental observables, such as NMR chemical shifts. ( 0,580753542277437 )
Comput Math Methods Med - Optimal control of HIV/AIDS in the workplace in the presence of careless individuals. ( 0,579928021544177 )
Comput Methods Programs Biomed - Quantitative thermodynamic predication of interactions between nucleic acid and non-nucleic acid species using Microsoft excel. ( 0,579631041755549 )
Comput. Biol. Med. - SITDEM: a simulation tool for disease/endpoint models of association studies based on single nucleotide polymorphism genotypes. ( 0,579568287218499 )
IEEE Trans Image Process - Efficiency of semi-implicit schemes for anisotropic diffusion in the hypercube. ( 0,572494072127344 )
Med Biol Eng Comput - A fluid-structure interaction model of the aortic valve with coaptation and compliant aortic root. ( 0,570209419278723 )
Methods Inf Med - An epidemiological modeling and data integration framework. ( 0,569672856100646 )
Comput. Biol. Med. - Network and Nakamura tridiagonal computational simulation of electrically-conducting biopolymer micro-morphic transport phenomena. ( 0,568093607087058 )
Comput. Biol. Med. - Numerical investigation into blood clotting at the bone-dental implant interface in the presence of an electrical stimulus. ( 0,567576976344439 )
J Biomed Inform - Cloud-based bioinformatics workflow platform for large-scale next-generation sequencing analyses. ( 0,567019499043511 )
Comput Math Methods Med - A numerical method of reduced complexity for simulating vascular hemodynamics using coupled 0D lumped and 1D wave propagation models. ( 0,565637583731972 )
Comput Math Methods Med - Towards patient-specific modeling of coronary hemodynamics in healthy and diseased state. ( 0,564669359526507 )
Comput Math Methods Med - Comparing statistical models to predict dengue fever notifications. ( 0,563149263493108 )
Comput Math Methods Med - Theorems and application of local activity of CNN with five state variables and one port. ( 0,562241277044991 )
Neural Comput - A principled dimension-reduction method for the population density approach to modeling networks of neurons with synaptic dynamics. ( 0,561522705357911 )
Comput. Biol. Med. - IVUSAngio tool: a publicly available software for fast and accurate 3D reconstruction of coronary arteries. ( 0,560349052531178 )
J Chem Inf Model - CYANOS: a data management system for natural product drug discovery efforts using cultured microorganisms. ( 0,560199123624032 )
J. Comput. Biol. - Is an intuitive convergence definition of molecular dynamics simulations solely based on the root mean square deviation possible? ( 0,560144705068239 )
Comput Methods Programs Biomed - A therapy parameter-based model for predicting blood glucose concentrations in patients with type 1 diabetes. ( 0,559226029905805 )
IEEE Trans Image Process - Box relaxation schemes in staggered discretizations for the dual formulation of total variation minimization. ( 0,558313981880762 )
J Chem Inf Model - Multiscale macromolecular simulation: role of evolving ensembles. ( 0,557853508147658 )
Comput. Biol. Med. - Mathematical modeling of brain glioma growth using modified reaction-diffusion equation on brain MR images. ( 0,557439088727485 )
Neural Comput - A systematic method for configuring VLSI networks of spiking neurons. ( 0,555416811645053 )
Comput Methods Programs Biomed - A theoretical model of dentinogenesis: dentin and dentinal tubule formation. ( 0,553238080654854 )
Int J Comput Assist Radiol Surg - The Medical Imaging Interaction Toolkit: challenges and advances : 10 years of open-source development. ( 0,552096527093758 )
Neural Comput - On the simulation of nonlinear bidimensional spiking neuron models. ( 0,552066634070466 )
BMC Med Inform Decis Mak - Clinical software development for the Web: lessons learned from the BOADICEA project. ( 0,55096002711671 )
Methods Inf Med - Enabling GeneHunter as a grid service: a case study for implementing analytical services in biomedical grids. ( 0,550205538490199 )
J Med Syst - Impact of the Patient-Reported Outcomes Management Information System (PROMIS) upon the design and operation of multi-center clinical trials: a qualitative research study. ( 0,549874786154699 )
Brief. Bioinformatics - Bioinformatics tools and database resources for systems genetics analysis in mice--a short review and an evaluation of future needs. ( 0,549508988757119 )
Lifetime Data Anal - Bayesian dynamic regression models for interval censored survival data with application to children dental health. ( 0,545818098187893 )
Med Biol Eng Comput - An improved curvilinear gradient method for parameter optimization in complex biological models. ( 0,545773682787422 )
Comput. Biol. Med. - Phase lagging model of brain response to external stimuli-modeling of single action potential. ( 0,545009143383482 )
Comput Methods Programs Biomed - Raw data extraction from electrocardiograms with Portable Document Format. ( 0,544760154416988 )
Appl Clin Inform - Design and multicentric implementation of a generic software architecture for patient recruitment systems re-using existing HIS tools and routine patient data. ( 0,543605829604061 )
Comput. Biol. Med. - An implicit evolution scheme for active contours and surfaces based on IIR filtering. ( 0,543264177676236 )
Int J Health Geogr - Displaying R spatial statistics on Google dynamic maps with web applications created by Rwui. ( 0,542420910783486 )
Med Biol Eng Comput - Model predictive control of relative blood volume and heart rate during hemodialysis. ( 0,542006935377095 )
Comput Math Methods Med - Simulations of complex and microscopic models of cardiac electrophysiology powered by multi-GPU platforms. ( 0,541976975933282 )
J Chem Inf Model - Fitting of dihedral terms in classical force fields as an analytic linear least-squares problem. ( 0,541314267930636 )