Int J Comput Assist Radiol Surg - A computer analysis method for correlating knee X-rays with continuous indicators.

Tópicos

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Resumo

RPOSE: To develop an image analysis method that can automatically find correlations between a set of plain radiographs and continuous clinical or physiological indicators.METHODS: Knee X-rays taken from the Baltimore Longitudinal Study of Aging are used in this study. The computer analysis method is based on the WND-CHARM image feature set filtered by using the Pearson correlation of each feature with the continuous variable, and the estimated value is determined by a weighted nearest neighbor interpolation.RESULTS: Experimental results using 300 radiographs show that the proposed method can correlate knee X-rays with physiological indicators such as sex, age, height, weight, and BMI. For instance, the Pearson correlation between the X-ray images and the height and weight were 0.59 and 0.62, respectively.CONCLUSIONS: Using computer analysis, X-ray images can be correlated to continuous physiological variables that might not have a direct and straightforward link to the visual content of the radiograph. This approach of radiology image analysis can be used in population studies for detecting biomarkers and also in genome-wide association studies for studying the link between genes and anatomy.

Resumo Limpo

rpose develop imag analysi method can automat find correl set plain radiograph continu clinic physiolog indicatorsmethod knee xray taken baltimor longitudin studi age use studi comput analysi method base wndcharm imag featur set filter use pearson correl featur continu variabl estim valu determin weight nearest neighbor interpolationresult experiment result use radiograph show propos method can correl knee xray physiolog indic sex age height weight bmi instanc pearson correl xray imag height weight respectivelyconclus use comput analysi xray imag can correl continu physiolog variabl might direct straightforward link visual content radiograph approach radiolog imag analysi can use popul studi detect biomark also genomewid associ studi studi link gene anatomi

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