Int J Comput Assist Radiol Surg - Optimal setting of image bounding box can improve registration accuracy of diffusion tensor tractography.


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RPOSE: When we register diffusion tensor tractography (DTT) to anatomical images such as fast imaging employing steady-state acquisition (FIESTA), we register the B0 image to FIESTA. Precise registration of the DTT B0 image to FIESTA is possible with non-rigid registration compared to rigid registration, although the non-rigid methods lack convenience. We report the effect of image data bounding box settings on registration accuracy using a normalized mutual information (NMI) method METHODS: MRI scans of 10 patients were used in this study. Registration was performed without modification of the bounding box in the control group, and the results were compared with groups re-registered using multiple bounding boxes limited to the region of interest (ROI). The distance of misalignment after registration at 3 anatomical characteristic points that are common to both FIESTA and B0 images was used as an index of accuracy.RESULTS: Mean ([Formula: see text]SD) misalignment at the 3 anatomical points decreased significantly from [Formula: see text] to [Formula: see text]?mm, [Formula: see text]), [Formula: see text] to [Formula: see text]?mm, ([Formula: see text], and [Formula: see text] to [Formula: see text]?mm, ([Formula: see text], each showing improvement compared to the control group CONCLUSION: Narrowing the image data bounding box to the ROI improves the accuracy of registering B0 images to FIESTA by NMI method. With our proposed methodology, accuracy can be improved in extremely easy steps, and this methodology may prove useful for DTT registration to anatomical image.

Resumo Limpo

rpose regist diffus tensor tractographi dtt anatom imag fast imag employ steadyst acquisit fiesta regist b imag fiesta precis registr dtt b imag fiesta possibl nonrigid registr compar rigid registr although nonrigid method lack conveni report effect imag data bound box set registr accuraci use normal mutual inform nmi method method mri scan patient use studi registr perform without modif bound box control group result compar group reregist use multipl bound box limit region interest roi distanc misalign registr anatom characterist point common fiesta b imag use index accuracyresult mean formula see textsd misalign anatom point decreas signific formula see text formula see textmm formula see text formula see text formula see textmm formula see text formula see text formula see textmm formula see text show improv compar control group conclus narrow imag data bound box roi improv accuraci regist b imag fiesta nmi method propos methodolog accuraci can improv extrem easi step methodolog may prove use dtt registr anatom imag

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