Int J Comput Assist Radiol Surg - Hybrid image visualization tool for 3D integration of CT coronary anatomy and quantitative myocardial perfusion PET.

Tópicos

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Resumo

RPOSE: Multimodal cardiac imaging by CTA and quantitative PET enables acquisition of patient-specific coronary anatomy and absolute myocardial perfusion at rest and during stress. In the clinical setting, integration of this information is performed visually or using coronary arteries distribution models. We developed a new tool for CTA and quantitative PET integrated 3D visualization, exploiting XML and DICOM clinical standards.METHODS: The hybrid image tool (HIT) developed in the present study included four main modules: (1) volumetric registration for spatial matching of CTA and PET data sets, (2) an interface to PET quantitative analysis software, (3) a derived DICOM generator able to build DICOM data set from quantitative polar maps, and (4) a 3D visualization tool of integrated anatomical and quantitative flow information. The four modules incorporated in the HIT tool communicate by defined standard XML files: XML-transformation and XML MIST standards.RESULTS: The HIT tool implements a 3D representation of CTA showing real coronary anatomy fused to PET-derived quantitative myocardial blood flow distribution. The technique was validated on 16 data sets from EVINCI study population. The validation of the method confirmed the high matching between "original" and derived data sets as well as the accuracy of the registration procedure.CONCLUSIONS: Three-dimensional integration of patient- specific coronary artery anatomy provided by CTA and quantitative myocardial blood flow obtained from PET imaging can improve cardiac disease assessment. The HIT tool introduced in this paper may represent a significant advancement in the clinical use of this multimodal approach.

Resumo Limpo

rpose multimod cardiac imag cta quantit pet enabl acquisit patientspecif coronari anatomi absolut myocardi perfus rest stress clinic set integr inform perform visual use coronari arteri distribut model develop new tool cta quantit pet integr d visual exploit xml dicom clinic standardsmethod hybrid imag tool hit develop present studi includ four main modul volumetr registr spatial match cta pet data set interfac pet quantit analysi softwar deriv dicom generat abl build dicom data set quantit polar map d visual tool integr anatom quantit flow inform four modul incorpor hit tool communic defin standard xml file xmltransform xml mist standardsresult hit tool implement d represent cta show real coronari anatomi fuse petderiv quantit myocardi blood flow distribut techniqu valid data set evinci studi popul valid method confirm high match origin deriv data set well accuraci registr procedureconclus threedimension integr patient specif coronari arteri anatomi provid cta quantit myocardi blood flow obtain pet imag can improv cardiac diseas assess hit tool introduc paper may repres signific advanc clinic use multimod approach

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