Int J Comput Assist Radiol Surg - Fetal brain volumetry through MRI volumetric reconstruction and segmentation.

Tópicos

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Resumo

RPOSE: Fetal MRI volumetry is a useful technique but it is limited by a dependency upon motion-free scans, tedious manual segmentation, and spatial inaccuracy due to thick-slice scans. An image processing pipeline that addresses these limitations was developed and tested.MATERIALS AND METHODS: The principal sequences acquired in fetal MRI clinical practice are multiple orthogonal single-shot fast spin echo scans. State-of-the-art image processing techniques were used for inter-slice motion correction and super-resolution reconstruction of high-resolution volumetric images from these scans. The reconstructed volume images were processed with intensity non-uniformity correction and the fetal brain extracted by using supervised automated segmentation.RESULTS: Reconstruction, segmentation and volumetry of the fetal brains for a cohort of twenty-five clinically acquired fetal MRI scans was done. Performance metrics for volume reconstruction, segmentation and volumetry were determined by comparing to manual tracings in five randomly chosen cases. Finally, analysis of the fetal brain and parenchymal volumes was performed based on the gestational age of the fetuses.CONCLUSION: The image processing pipeline developed in this study enables volume rendering and accurate fetal brain volumetry by addressing the limitations of current volumetry techniques, which include dependency on motion-free scans, manual segmentation, and inaccurate thick-slice interpolation.

Resumo Limpo

rpose fetal mri volumetri use techniqu limit depend upon motionfre scan tedious manual segment spatial inaccuraci due thickslic scan imag process pipelin address limit develop testedmateri method princip sequenc acquir fetal mri clinic practic multipl orthogon singleshot fast spin echo scan stateoftheart imag process techniqu use interslic motion correct superresolut reconstruct highresolut volumetr imag scan reconstruct volum imag process intens nonuniform correct fetal brain extract use supervis autom segmentationresult reconstruct segment volumetri fetal brain cohort twentyf clinic acquir fetal mri scan done perform metric volum reconstruct segment volumetri determin compar manual trace five random chosen case final analysi fetal brain parenchym volum perform base gestat age fetusesconclus imag process pipelin develop studi enabl volum render accur fetal brain volumetri address limit current volumetri techniqu includ depend motionfre scan manual segment inaccur thickslic interpol

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