Int J Comput Assist Radiol Surg - Intraoperative segmentation of iodine and palladium radioactive sources in C-arm images.

Tópicos

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Resumo

RPOSE: Dynamic dosimetry is becoming the standard to evaluate the quality of radioactive implants during brachytherapy. For this, it is essential to obtain a 3D visualization of the implanted seeds and their relative position to the prostate. A method was developed to obtain a robust and precise segmentation of seeds in C-arm images, and this approach was tested using clinical datasets.METHOD: A region-based implicit active contour approach was used to delineate implanted seeds. Then, a template-based matching was employed to segment iodine implants whereas a K-means algorithm is implemented to resolve palladium seed clusters. To validate the method, 55 C-arm images from 10 patients were used for the segmentation of iodine sources, whereas 225 C-arm images from 16 patients were used for the palladium case.RESULTS: Compared to manual ground truth segmentation of 6,002 iodine seeds and 15,354 palladium seeds, 98.7 % of iodine sources were automatically detected and declustered showing a false-positive rate of only 1.7 %. A total of 98.7 % of palladium sources were automatically detected and declustered with a false-positive rate of only 2.0 %.CONCLUSION: An automated segmentation method was developed that is able to perform the identification and annotation processes of seeds on par with a human expert. This method was shown to be robust and suitable for integration in the dynamic dosimetry workflow of prostate brachytherapy interventions.

Resumo Limpo

rpose dynam dosimetri becom standard evalu qualiti radioact implant brachytherapi essenti obtain d visual implant seed relat posit prostat method develop obtain robust precis segment seed carm imag approach test use clinic datasetsmethod regionbas implicit activ contour approach use delin implant seed templatebas match employ segment iodin implant wherea kmean algorithm implement resolv palladium seed cluster valid method carm imag patient use segment iodin sourc wherea carm imag patient use palladium caseresult compar manual ground truth segment iodin seed palladium seed iodin sourc automat detect declust show falseposit rate total palladium sourc automat detect declust falseposit rate conclus autom segment method develop abl perform identif annot process seed par human expert method shown robust suitabl integr dynam dosimetri workflow prostat brachytherapi intervent

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