Int J Neural Syst - Cortical excitability and refractory epilepsy: a three-year longitudinal transcranial magnetic stimulation study.

Tópicos

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Resumo

Transcranial magnetic stimulation was used to study the effect of recurrent seizures on cortical excitability over time in epilepsy. 77 patients with firm diagnoses of idiopathic generalized epilepsy (IGE) or focal epilepsy were repeatedly evaluated over three years. At onset, all groups had increased cortical excitability. At the end of follow-up the refractory group was associated with a broad increase in cortical excitability. Conversely, cortical excitability decreased in all seizure free groups after introduction of an effective medication.

Resumo Limpo

transcrani magnet stimul use studi effect recurr seizur cortic excit time epilepsi patient firm diagnos idiopath general epilepsi ige focal epilepsi repeat evalu three year onset group increas cortic excit end followup refractori group associ broad increas cortic excit convers cortic excit decreas seizur free group introduct effect medic

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