Int J Neural Syst - A new work mechanism on neuronal activity.

Tópicos

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Resumo

By re-examining the neuronal activity energy model, we show the inadequacies in the current understanding of the energy consumption associated with neuron activity. Specifically, we show computationally that a neuron first absorbs and then consumes energy during firing action potential, and this result cannot be produced from any current neuron models or biological neural networks. Based on this finding, we provide an explanation for the observation that when neurons are excited in the brain, blood flow increases significantly while the incremental oxygen consumption is very small. We can also explain why external stimulation and perception emergence are synchronized. We also show that negative energy presence in neurons at the sub-threshold state is an essential reason that leads to blood flow incremental response time in the brain rather than neural excitation to delay.

Resumo Limpo

reexamin neuron activ energi model show inadequaci current understand energi consumpt associ neuron activ specif show comput neuron first absorb consum energi fire action potenti result produc current neuron model biolog neural network base find provid explan observ neuron excit brain blood flow increas signific increment oxygen consumpt small can also explain extern stimul percept emerg synchron also show negat energi presenc neuron subthreshold state essenti reason lead blood flow increment respons time brain rather neural excit delay

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