Appl Clin Inform - IT Infrastructure Components for Biobanking.

Tópicos

{ data(1714) softwar(1251) tool(1186) }
{ framework(1458) process(801) describ(734) }
{ implement(1333) system(1263) develop(1122) }
{ concept(1167) ontolog(924) domain(897) }
{ algorithm(1844) comput(1787) effici(935) }
{ motion(1329) object(1292) video(1091) }
{ design(1359) user(1324) use(1319) }
{ sampl(1606) size(1419) use(1276) }
{ search(2224) databas(1162) retriev(909) }
{ research(1085) discuss(1038) issu(1018) }
{ research(1218) medic(880) student(794) }
{ can(981) present(881) function(850) }
{ extract(1171) text(1153) clinic(932) }
{ control(1307) perform(991) simul(935) }
{ system(1050) medic(1026) inform(1018) }
{ use(976) code(926) identifi(902) }
{ problem(2511) optim(1539) algorithm(950) }
{ clinic(1479) use(1117) guidelin(835) }
{ data(3008) multipl(1320) sourc(1022) }
{ first(2504) two(1366) second(1323) }
{ intervent(3218) particip(2042) group(1664) }
{ patient(1821) servic(1111) care(1106) }
{ analysi(2126) use(1163) compon(1037) }
{ high(1669) rate(1365) level(1280) }
{ can(774) often(719) complex(702) }
{ data(1737) use(1416) pattern(1282) }
{ inform(2794) health(2639) internet(1427) }
{ studi(2440) review(1878) systemat(933) }
{ general(901) number(790) one(736) }
{ case(1353) use(1143) diagnosi(1136) }
{ howev(809) still(633) remain(590) }
{ risk(3053) factor(974) diseas(938) }
{ record(1888) medic(1808) patient(1693) }
{ health(3367) inform(1360) care(1135) }
{ model(3480) simul(1196) paramet(876) }
{ monitor(1329) mobil(1314) devic(1160) }
{ patient(2837) hospit(1953) medic(668) }
{ cancer(2502) breast(956) screen(824) }
{ detect(2391) sensit(1101) algorithm(908) }
{ model(3404) distribut(989) bayesian(671) }
{ imag(1947) propos(1133) code(1026) }
{ system(1976) rule(880) can(841) }
{ measur(2081) correl(1212) valu(896) }
{ imag(1057) registr(996) error(939) }
{ bind(1733) structur(1185) ligand(1036) }
{ sequenc(1873) structur(1644) protein(1328) }
{ method(1219) similar(1157) match(930) }
{ featur(3375) classif(2383) classifi(1994) }
{ imag(2830) propos(1344) filter(1198) }
{ network(2748) neural(1063) input(814) }
{ imag(2675) segment(2577) method(1081) }
{ patient(2315) diseas(1263) diabet(1191) }
{ take(945) account(800) differ(722) }
{ assess(1506) score(1403) qualiti(1306) }
{ treatment(1704) effect(941) patient(846) }
{ surgeri(1148) surgic(1085) robot(1054) }
{ error(1145) method(1030) estim(1020) }
{ chang(1828) time(1643) increas(1301) }
{ learn(2355) train(1041) set(1003) }
{ method(1557) propos(1049) approach(1037) }
{ model(2220) cell(1177) simul(1124) }
{ care(1570) inform(1187) nurs(1089) }
{ method(984) reconstruct(947) comput(926) }
{ featur(1941) imag(1645) propos(1176) }
{ data(3963) clinic(1234) research(1004) }
{ studi(1410) differ(1259) use(1210) }
{ perform(999) metric(946) measur(919) }
{ import(1318) role(1303) understand(862) }
{ model(2341) predict(2261) use(1141) }
{ visual(1396) interact(850) tool(830) }
{ compound(1573) activ(1297) structur(1058) }
{ perform(1367) use(1326) method(1137) }
{ studi(1119) effect(1106) posit(819) }
{ blood(1257) pressur(1144) flow(957) }
{ spatial(1525) area(1432) region(1030) }
{ ehr(2073) health(1662) electron(1139) }
{ state(1844) use(1261) util(961) }
{ model(2656) set(1616) predict(1553) }
{ data(2317) use(1299) case(1017) }
{ age(1611) year(1155) adult(843) }
{ medic(1828) order(1363) alert(1069) }
{ signal(2180) analysi(812) frequenc(800) }
{ cost(1906) reduc(1198) effect(832) }
{ group(2977) signific(1463) compar(1072) }
{ gene(2352) biolog(1181) express(1162) }
{ activ(1138) subject(705) human(624) }
{ time(1939) patient(1703) rate(768) }
{ use(2086) technolog(871) perceiv(783) }
{ health(1844) social(1437) communiti(874) }
{ structur(1116) can(940) graph(676) }
{ use(1733) differ(960) four(931) }
{ drug(1928) target(777) effect(648) }
{ result(1111) use(1088) new(759) }
{ survey(1388) particip(1329) question(1065) }
{ estim(2440) model(1874) function(577) }
{ decis(3086) make(1611) patient(1517) }
{ process(1125) use(805) approach(778) }
{ activ(1452) weight(1219) physic(1104) }
{ method(1969) cluster(1462) data(1082) }
{ method(2212) result(1239) propos(1039) }

Resumo

JECTIVE: Within translational research projects in the recent years large biobanks have been established, mostly supported by homegrown, proprietary software solutions. No general requirements for biobanking IT infrastructures have been published yet. This paper presents an exemplary biobanking IT architecture, a requirements specification for a biorepository management tool and exemplary illustrations of three major types of requirements.METHODS: We have pursued a comprehensive literature review for biobanking IT solutions and established an interdisciplinary expert panel for creating the requirements specification. The exemplary illustrations were derived from a requirements analysis within two university hospitals.RESULTS: The requirements specification comprises a catalog with more than 130 detailed requirements grouped into 3 major categories and 20 subcategories. Special attention is given to multitenancy capabilities in order to support the project-specific definition of varying research and bio-banking contexts, the definition of workflows to track sample processing, sample transportation and sample storage and the automated integration of preanalytic handling and storage robots.CONCLUSION: IT support for biobanking projects can be based on a federated architectural framework comprising primary data sources for clinical annotations, a pseudonymization service, a clinical data warehouse with a flexible and user-friendly query interface and a biorepository management system. Flexibility and scalability of all such components are vital since large medical facilities such as university hospitals will have to support biobanking for varying monocentric and multicentric research scenarios and multiple medical clients.

Resumo Limpo

jectiv within translat research project recent year larg biobank establish most support homegrown proprietari softwar solut general requir biobank infrastructur publish yet paper present exemplari biobank architectur requir specif biorepositori manag tool exemplari illustr three major type requirementsmethod pursu comprehens literatur review biobank solut establish interdisciplinari expert panel creat requir specif exemplari illustr deriv requir analysi within two univers hospitalsresult requir specif compris catalog detail requir group major categori subcategori special attent given multiten capabl order support projectspecif definit vari research biobank context definit workflow track sampl process sampl transport sampl storag autom integr preanalyt handl storag robotsconclus support biobank project can base feder architectur framework compris primari data sourc clinic annot pseudonym servic clinic data warehous flexibl userfriend queri interfac biorepositori manag system flexibl scalabl compon vital sinc larg medic facil univers hospit will support biobank vari monocentr multicentr research scenario multipl medic client

Resumos Similares

Comput Methods Programs Biomed - AIBench: a rapid application development framework for translational research in biomedicine. ( 0,744648423873454 )
AMIA Annu Symp Proc - The TRITON Project: Design and Implementation of an Integrative Translational Research Information Management Platform. ( 0,64885870612381 )
J Biomed Inform - NanoParticle Ontology for cancer nanotechnology research. ( 0,636292278710052 )
Comput. Biol. Med. - A robust and extendible framework for medical image registration focused on rapid clinical application deployment. ( 0,630732791118721 )
Methods Inf Med - The integration of the risk management process with the lifecycle of medical device software. ( 0,622458886429417 )
J. Med. Internet Res. - The behavioral intervention technology model: an integrated conceptual and technological framework for eHealth and mHealth interventions. ( 0,62110816120264 )
IEEE Trans Vis Comput Graph - A Survey of Software Frameworks for Cluster-Based Large High-Resolution Displays. ( 0,619599447786664 )
IEEE J Biomed Health Inform - Automatic handling of tissue microarray cores in high-dimensional microscopy images. ( 0,618653357650898 )
BMC Med Inform Decis Mak - Semantic text mining support for lignocellulose research. ( 0,615697720207715 )
Comput Methods Programs Biomed - Software for quantitative analysis of radiotherapy: overview, requirement analysis and design solutions. ( 0,611770648116625 )
Med Biol Eng Comput - Towards a flexible middleware for context-aware pervasive and wearable systems. ( 0,608896316923869 )
Comput Biol Chem - Monte Carlo-based rigid body modelling of large protein complexes against small angle scattering data. ( 0,598233236288574 )
Appl Clin Inform - Design and multicentric implementation of a generic software architecture for patient recruitment systems re-using existing HIS tools and routine patient data. ( 0,595071992327938 )
Telemed J E Health - Uncompressed high-definition videoconferencing tools for telemedicine and distance learning. ( 0,592101711399787 )
Methods Inf Med - Architectural approaches for HL7-based health information systems implementation. ( 0,59187974350479 )
Brief. Bioinformatics - The semantic web in translational medicine: current applications and future directions. ( 0,591463111498275 )
J Am Med Inform Assoc - Enabling collaborative research using the Biomedical Informatics Research Network (BIRN). ( 0,587803647596529 )
BMC Med Inform Decis Mak - Decision support at home (DS@HOME)--system architectures and requirements. ( 0,587603457153518 )
Comput Methods Programs Biomed - Five-year experience with setup and implementation of an integrated database system for clinical documentation and research. ( 0,586595918863384 )
Int J Comput Assist Radiol Surg - The Medical Imaging Interaction Toolkit: challenges and advances : 10 years of open-source development. ( 0,582477133702428 )
Telemed J E Health - Conceptual framework for development of comprehensive e-health evaluation tool. ( 0,58214264526277 )
J Integr Bioinform - BacillOndex: an integrated data resource for systems and synthetic biology. ( 0,581669895005388 )
Wiley Interdiscip Rev Syst Biol Med - Accelerating cancer systems biology research through Semantic Web technology. ( 0,580832988274472 )
Methods Inf Med - Enabling GeneHunter as a grid service: a case study for implementing analytical services in biomedical grids. ( 0,580261817920139 )
J Integr Bioinform - Tracking T and B cells from two-photon microscopy imaging using constrained SMC clusters. ( 0,579940703033505 )
Comput Methods Programs Biomed - An open-source, FireWire camera-based, Labview-controlled image acquisition system for automated, dynamic pupillometry and blink detection. ( 0,577159444160586 )
J Med Syst - A user-centered, object-oriented methodology for developing Health Information Systems: a Clinical Information System (CIS) example. ( 0,573306282324663 )
J Am Med Inform Assoc - Implementation of a deidentified federated data network for population-based cohort discovery. ( 0,572632282463579 )
Brief. Bioinformatics - The NGS WikiBook: a dynamic collaborative online training effort with long-term sustainability. ( 0,572472422842375 )
J Chem Inf Model - Digital data repositories in chemistry and their integration with journals and electronic notebooks. ( 0,570728179992415 )
J. Med. Internet Res. - Can social semantic web techniques foster collaborative curriculum mapping in medicine? ( 0,56829007784308 )
J Biomed Inform - The ACGT Master Ontology and its applications--towards an ontology-driven cancer research and management system. ( 0,566720148746959 )
Comput Methods Programs Biomed - Using off-the-shelf tools for terabyte-scale waveform recording in intensive care: computer system design, database description and lessons learned. ( 0,565926015283648 )
J Chem Inf Model - DDLm: a new dictionary definition language. ( 0,562659482229647 )
Int J Med Inform - Development and evaluation of SOA-based AAL services in real-life environments: a case study and lessons learned. ( 0,561516343548321 )
AMIA Annu Symp Proc - Collaborative development and maintenance of health terminologies. ( 0,561105288411207 )
BMC Med Inform Decis Mak - AGUIA: autonomous graphical user interface assembly for clinical trials semantic data services. ( 0,560024806160015 )
Sci Data - Metabolic differences in ripening of Solanum lycopersicum 'Ailsa Craig' and three monogenic mutants. ( 0,559466458010772 )
J Biomed Inform - Modular design, application architecture, and usage of a self-service model for enterprise data delivery: the Duke Enterprise Data Unified Content Explorer (DEDUCE). ( 0,558995224930364 )
Brief. Bioinformatics - Tutorial videos of bioinformatics resources: online distribution trial in Japan named TogoTV. ( 0,558635395330843 )
AMIA Annu Symp Proc - Evaluation of need for ontologies to manage domain content for the Reportable Conditions Knowledge Management System. ( 0,557689533018865 )
J Am Med Inform Assoc - Taking advantage of continuity of care documents to populate a research repository. ( 0,55745944724973 )
Brief. Bioinformatics - A toolbox for developing bioinformatics software. ( 0,556927644633095 )
J Am Med Inform Assoc - An optimized web-based approach for collaborative stereoscopic medical visualization. ( 0,555172821202978 )
J Integr Bioinform - Bio-Search Computing: integration and global ranking of bioinformatics search results. ( 0,553412017148431 )
Methods Inf Med - Putting biomedical ontologies to work. ( 0,553033160950627 )
J Integr Bioinform - UBioLab: a web-laboratory for ubiquitous in-silico experiments. ( 0,552897443113955 )
J Med Syst - MEDWISE: an innovative public health information system infrastructure. ( 0,551374274642327 )
BMC Med Inform Decis Mak - The challenges of real-world implementation of web-based shared care software: the HopSCOTCH Shared-Care Obesity Trial in Children. ( 0,551212583665467 )
AMIA Annu Symp Proc - The ontology life cycle: Integrated tools for editing, publishing, peer review, and evolution of ontologies. ( 0,550527611966431 )
Methods Inf Med - Testing conformance and interoperability of eHealth applications. ( 0,549533469994072 )
AMIA Annu Symp Proc - Medication Reconciliation: Work Domain Ontology, prototype development, and a predictive model. ( 0,548763811764187 )
Methods Inf Med - Missing semantic annotation in databases. The root cause for data integration and migration problems in information systems. ( 0,548562015403139 )
Int J Health Geogr - Open-Source web-based Geographical Information System for health exposure assessment. ( 0,547853846784169 )
Brief. Bioinformatics - Knowledge sharing and collaboration in translational research, and the DC-THERA Directory. ( 0,547185506781053 )
AMIA Annu Symp Proc - ARX--A Comprehensive Tool for Anonymizing Biomedical Data. ( 0,546371093460648 )
Health Informatics J - Evaluation of ISO EN 13606 as a result of its implementation in XML. ( 0,545336112249942 )
Methods Inf Med - A task-based support architecture for developing point-of-care clinical decision support systems for the emergency department. ( 0,544278591703088 )
Comput Methods Programs Biomed - SAPPHIRE: a toolkit for building efficient stream programs for medical video analysis. ( 0,54169080736934 )
Telemed J E Health - An Albanian open source telemedicine platform. ( 0,54064700593115 )
J. Med. Internet Res. - Retaining critical therapeutic elements of behavioral interventions translated for delivery via the Internet: recommendations and an example using pain coping skills training. ( 0,539651259048666 )
Comput Methods Programs Biomed - Facilitating pharmacometric workflow with the metrumrg package for R. ( 0,536891780696889 )
Curr Protoc Bioinformatics - Using EMBL-EBI Services via Web Interface and Programmatically via Web Services. ( 0,536071976152185 )
Brief. Bioinformatics - RegScan: a GWAS tool for quick estimation of allele effects on continuous traits and their combinations. ( 0,535582535825397 )
AMIA Annu Symp Proc - Use of Design Science for Informing the Development of a Mobile App for Persons Living with HIV. ( 0,5354034024601 )
Methods Inf Med - Supporting translational research on inherited cardiomyopathies through information technology. ( 0,535142015018267 )
J Chem Inf Model - Designing a new Diels-Alderase: a combinatorial, semirational approach including dynamic optimization. ( 0,533822695812801 )
BMC Med Inform Decis Mak - Development and formative evaluation of the e-Health Implementation Toolkit (e-HIT). ( 0,533509866791899 )
J. Med. Internet Res. - The virtual skeleton database: an open access repository for biomedical research and collaboration. ( 0,53338109541968 )
Comput Methods Programs Biomed - Development of a new software for comprehensive management and traceability of hospital radiopharmacies. ( 0,533311478198061 )
IEEE J Biomed Health Inform - Semantic Normalization and Query Abstraction Based on SNOMED-CT and HL7: Supporting Multicentric Clinical Trials. ( 0,533306456069906 )
BMC Med Inform Decis Mak - GliomaPredict: a clinically useful tool for assigning glioma patients to specific molecular subtypes. ( 0,532243617864307 )
Brief. Bioinformatics - Challenges in integrating Escherichia coli molecular biology data. ( 0,532223340812401 )
IEEE Trans Image Process - Universal regularizers for robust sparse coding and modeling. ( 0,532145831285969 )
IEEE Trans Vis Comput Graph - Drawing Euler Diagrams with Circles: The Theory of Piercings. ( 0,531521809254812 )
J Clin Monit Comput - Integrating Arden-Syntax-based clinical decision support with extended presentation formats into a commercial patient data management system. ( 0,52989232207809 )
BMC Med Inform Decis Mak - e-MIR2: a public online inventory of medical informatics resources. ( 0,528783914110618 )
IEEE Trans Image Process - Blur invariants constructed from arbitrary moments. ( 0,52804822407263 )
J Biomed Inform - A robust and simple security extension for the medical standard SCP-ECG. ( 0,527245719172824 )
AMIA Annu Symp Proc - Temporal abstraction-based clinical phenotyping with Eureka! ( 0,526857126598793 )
J Integr Bioinform - A flexible statistics web processing service--added value for information systems for experiment data. ( 0,526640980822828 )
Int J Med Inform - Using ontologies for structuring organizational knowledge in Home Care assistance. ( 0,524912438554881 )
J Am Med Inform Assoc - An i2b2-based, generalizable, open source, self-scaling chronic disease registry. ( 0,523933746201347 )
Int J Comput Assist Radiol Surg - MITK-US: real-time ultrasound support within MITK. ( 0,523819636197173 )
Methods Inf Med - Potential and requirements of IT for ambient assisted living technologies. Results of a Delphi study. ( 0,522925569398546 )
J Am Med Inform Assoc - Computerization of workflows, guidelines, and care pathways: a review of implementation challenges for process-oriented health information systems. ( 0,522712230458968 )
Med Biol Eng Comput - FieldML, a proposed open standard for the Physiome project for mathematical model representation. ( 0,52238624645561 )
Healthc (Amst) - Supporting HITECH implementation and assessing lessons for the future: The role of program evaluation. ( 0,522122962231472 )
J Biomed Inform - Cloud-based bioinformatics workflow platform for large-scale next-generation sequencing analyses. ( 0,521149242004683 )
J. Med. Internet Res. - A framework for characterizing eHealth literacy demands and barriers. ( 0,520416554154769 )
Brief. Bioinformatics - Architecture for interoperable software in biology. ( 0,519915701347124 )
J Med Syst - Research on application information system integration platform in medicine manufacturing enterprise. ( 0,519490550998718 )
BMC Med Inform Decis Mak - Open source challenges for hospital information system (HIS) in developing countries: a pilot project in Mali. ( 0,518122490734663 )
Methods Inf Med - Architectural approach to eHealth for enabling paradigm changes in health. ( 0,517775804519375 )
BMC Med Inform Decis Mak - Adaptation of a web-based, open source electronic medical record system platform to support a large study of tuberculosis epidemiology. ( 0,516812411405889 )
Methods Inf Med - The role of taxonomies in social media and the semantic web for health education. A study of SNOMED CT terms in YouTube health video tags. ( 0,516600872471797 )
AMIA Annu Symp Proc - A cloud-based simulation architecture for pandemic influenza simulation. ( 0,516556279806734 )
IEEE Trans Image Process - Adaptive appearance modeling for video tracking: survey and evaluation. ( 0,515734077078804 )
J Biomed Inform - Discovering beaten paths in collaborative ontology-engineering projects using Markov chains. ( 0,514641673373506 )
BMC Med Inform Decis Mak - Applying representational state transfer (REST) architecture to archetype-based electronic health record systems. ( 0,514149705281158 )