J Am Med Inform Assoc - R engine cell: integrating R into the i2b2 software infrastructure.

Tópicos

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{ data(2317) use(1299) case(1017) }
{ age(1611) year(1155) adult(843) }
{ medic(1828) order(1363) alert(1069) }
{ signal(2180) analysi(812) frequenc(800) }
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{ group(2977) signific(1463) compar(1072) }
{ sampl(1606) size(1419) use(1276) }
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{ cancer(2502) breast(956) screen(824) }
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{ result(1111) use(1088) new(759) }
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{ process(1125) use(805) approach(778) }
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{ method(1969) cluster(1462) data(1082) }
{ detect(2391) sensit(1101) algorithm(908) }

Resumo

Informatics for Integrating Biology and the Bedside (i2b2) is an initiative funded by the NIH that aims at building an informatics infrastructure to support biomedical research. The University of Pavia has recently integrated i2b2 infrastructure with a registry of inherited arrhythmogenic diseases. Within this project, the authors created a novel i2b2 cell, named R Engine Cell, which allows the communication between i2b2 and the R statistical software. As survival analyses are routinely performed by cardiology researchers, the authors have first concentrated on making Kaplan-Meier analyses available within the i2b2 web interface. To this aim, the authors developed a web-client plug-in to select the patient set on which to perform the analysis and to display the results in a graphical, intuitive way. R Engine Cell has been designed to easily support the integration of other R-based statistical analyses into i2b2.

Resumo Limpo

informat integr biolog bedsid ib initi fund nih aim build informat infrastructur support biomed research univers pavia recent integr ib infrastructur registri inherit arrhythmogen diseas within project author creat novel ib cell name r engin cell allow communic ib r statist softwar surviv analys routin perform cardiolog research author first concentr make kaplanmei analys avail within ib web interfac aim author develop webclient plugin select patient set perform analysi display result graphic intuit way r engin cell design easili support integr rbase statist analys ib

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