J Am Med Inform Assoc - A taste of individualized medicine: physicians' reactions to automated genetic interpretations.

Tópicos

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{ age(1611) year(1155) adult(843) }
{ medic(1828) order(1363) alert(1069) }
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Resumo

The potential of pharmacogenomics is well documented, and functionality exploiting this knowledge is about to be introduced into electronic medical records. To explore physicians' reactions to automatic interpretations of genetic tests, we built a prototype with a simple interpretive algorithm. The algorithm was adapted to the needs of physicians handling immunosuppressive treatment during organ transplantation. Nine physicians were observed expressing their thoughts while using the prototype for two patient scenarios. The computer screen and audio were recorded, and the qualitative results triangulated with responses to a survey instrument. The physicians' reactions to the prototype were very positive; they clearly trusted the results and the theory behind them. The explanation of the algorithm was prominently placed in the user interface for transparency, although this design led to considerable confusion. Background information and references should be available, but considerably less prominent than the result and recommendation.

Resumo Limpo

potenti pharmacogenom well document function exploit knowledg introduc electron medic record explor physician reaction automat interpret genet test built prototyp simpl interpret algorithm algorithm adapt need physician handl immunosuppress treatment organ transplant nine physician observ express thought use prototyp two patient scenario comput screen audio record qualit result triangul respons survey instrument physician reaction prototyp posit clear trust result theori behind explan algorithm promin place user interfac transpar although design led consider confus background inform refer avail consider less promin result recommend

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