Tópico 10

Palavras

sequenc ( 1873 )
structur ( 1644 )
protein ( 1328 )
function ( 840 )
predict ( 615 )
align ( 552 )
genom ( 485 )
read ( 305 )
similar ( 296 )
human ( 278 )
base ( 262 )
acid ( 258 )
length ( 246 )
composit ( 236 )
fold ( 235 )
dna ( 224 )
secondari ( 193 )
famili ( 193 )
residu ( 191 )
site ( 187 )
character ( 185 )
biolog ( 184 )
evolut ( 176 )
generat ( 166 )
conserv ( 146 )
well ( 141 )
domain ( 137 )
short ( 131 )
repeat ( 129 )
region ( 126 )
avail ( 123 )
essenti ( 118 )
identif ( 115 )
organ ( 107 )
comparison ( 107 )
close ( 106 )
properti ( 94 )
sinc ( 94 )
mani ( 92 )
various ( 89 )
contain ( 89 )
assign ( 87 )
bioinformat ( 87 )
variant ( 84 )
determin ( 84 )
call ( 79 )
complex ( 79 )
experiment ( 77 )
window ( 76 )
entir ( 72 )
known ( 71 )
uniqu ( 69 )
recent ( 66 )
class ( 66 )
unknown ( 64 )
whole ( 64 )
core ( 64 )
comput ( 58 )
larg ( 56 )
ident ( 54 )
refer ( 53 )
alon ( 51 )
import ( 48 )
appli ( 47 )
reli ( 45 )
subsequ ( 44 )
novel ( 44 )
infer ( 44 )
reveal ( 41 )
exhibit ( 40 )
three ( 39 )
key ( 37 )
yield ( 36 )
exist ( 36 )
annot ( 35 )
freeli ( 34 )
maintain ( 34 )
profil ( 33 )
far ( 32 )
highthroughput ( 30 )
observ ( 29 )
find ( 29 )
chain ( 29 )
classic ( 29 )
respect ( 28 )
correct ( 28 )
shift ( 27 )
approach ( 25 )
start ( 22 )
therefor ( 22 )
topolog ( 22 )
latter ( 21 )
correspond ( 20 )
attract ( 19 )
enabl ( 17 )
introduc ( 17 )
best ( 17 )
new ( 16 )
now ( 16 )
fundament ( 15 )

Resumos

J Chem Inf Model - Protein secondary structure prediction with SPARROW. ( 63 )
Comput Biol Chem - Analysis of sequence repeats of proteins in the PDB. ( 48 )
Comput Methods Programs Biomed - Sequence-based prediction of protein-binding sites in DNA: comparative study of two SVM models. ( 46 )
Comput Biol Chem - Protein fold recognition based on functional domain composition. ( 42 )
BMC Med Inform Decis Mak - Efficient protein structure search using indexing methods. ( 40 )
Brief. Bioinformatics - De novo assembly of short sequence reads. ( 39 )
J. Comput. Biol. - ComB: SNP calling and mapping analysis for color and nucleotide space platforms. ( 39 )
J. Comput. Biol. - Efficient traversal of beta-sheet protein folding pathways using ensemble models. ( 36 )
Comput. Biol. Med. - Improving protein secondary structure prediction using a multi-modal BP method. ( 35 )
J Integr Bioinform - Complementarity of network and sequence information in homologous proteins. ( 35 )
Comput Biol Chem - Statistical analysis and exposure status classification of transmembrane beta barrel residues. ( 34 )
J Integr Bioinform - A hierarchical approach to protein fold prediction. ( 34 )
Comput Biol Chem - Characterizing regions in the human genome unmappable by next-generation-sequencing at the read length of 1000 bases. ( 33 )
J Chem Inf Model - Context-based features enhance protein secondary structure prediction accuracy. ( 32 )
Comput Biol Chem - ProSTRIP: A method to find similar structural repeats in three-dimensional protein structures. ( 31 )
Comput Biol Chem - Identification of putative and potential cross-reactive chickpea (Cicer arietinum) allergens through an in silico approach. ( 31 )
J Chem Inf Model - Building a knowledge-based statistical potential by capturing high-order inter-residue interactions and its applications in protein secondary structure assessment. ( 31 )
Comput Biol Chem - Identification and characterization of lysine-methylated sites on histones and non-histone proteins. ( 30 )
Brief. Bioinformatics - BamView: visualizing and interpretation of next-generation sequencing read alignments. ( 30 )
Brief. Bioinformatics - Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. ( 30 )
J Chem Inf Model - Comparative analysis of threshold and tessellation methods for determining protein contacts. ( 30 )
Brief. Bioinformatics - A practical guide for the computational selection of residues to be experimentally characterized in protein families. ( 29 )
Comput Biol Chem - Bacterial protein structures reveal phylum dependent divergence. ( 29 )
J Chem Inf Model - Protein secondary structure classification revisited: processing DSSP information with PSSC. ( 29 )
J Chem Inf Model - Modules identification in protein structures: the topological and geometrical solutions. ( 29 )
Comput Biol Chem - The frequency of poly(G) tracts in the human genome and their use as a sensor of DNA damage. ( 28 )
Comput. Biol. Med. - An insight into the molecular basis for convergent evolution in fish antifreeze Proteins. ( 28 )
Comput. Biol. Med. - Signal peptide discrimination and cleavage site identification using SVM and NN. ( 28 )
Comput. Biol. Med. - Predicting protein-binding RNA nucleotides using the feature-based removal of data redundancy and the interaction propensity of nucleotide triplets. ( 28 )
Brief. Bioinformatics - Taxonomic binning of metagenome samples generated by next-generation sequencing technologies. ( 27 )
Comput. Biol. Med. - A content and structural assessment of oxidative motifs across a diverse set of life forms. ( 27 )
Comput. Biol. Med. - New layers in understanding and predicting a-linolenic acid content in plants using amino acid characteristics of omega-3 fatty acid desaturase. ( 27 )
J Chem Inf Model - Parallel and antiparallel ?-strands differ in amino acid composition and availability of short constituent sequences. ( 27 )
J. Comput. Biol. - Simultaneous alignment and folding of protein sequences. ( 27 )
J Integr Bioinform - Predicting protein distance maps according to physicochemical properties. ( 27 )
Comput Biol Chem - Subgrouping Automata: automatic sequence subgrouping using phylogenetic tree-based optimum subgrouping algorithm. ( 26 )
Comput Biol Chem - Comparison of linear gap penalties and profile-based variable gap penalties in profile-profile alignments. ( 26 )
Comput Biol Chem - Semantically predicting protein functions based on protein functional connectivity. ( 26 )
J. Comput. Biol. - AREM: aligning short reads from ChIP-sequencing by expectation maximization. ( 26 )
J. Comput. Biol. - A Bayesian approach for determining protein side-chain rotamer conformations using unassigned NOE data. ( 26 )
Comput Biol Chem - ProCoCoA: A quantitative approach for analyzing protein core composition. ( 25 )
Comput Biol Chem - A local average connectivity-based method for identifying essential proteins from the network level. ( 25 )
Comput. Biol. Med. - A context evaluation approach for structural comparison of proteins using cross entropy over n-gram modelling. ( 25 )
J Chem Inf Model - PocketAlign a novel algorithm for aligning binding sites in protein structures. ( 25 )
J Biomed Inform - A similarity network approach for the analysis and comparison of protein sequence/structure sets. ( 25 )
J. Comput. Biol. - Detection of structural variants involving repetitive regions in the reference genome. ( 25 )
Med Biol Eng Comput - Enhanced spatio-temporal alignment of plantar pressure image sequences using B-splines. ( 25 )
Comput Biol Chem - Investigating long range correlation in DNA sequences using significance tests of conditional mutual information. ( 24 )
Comput Biol Chem - Gene expression regulation of the PF00480 or PF14340 domain proteins suggests their involvement in sulfur metabolism. ( 24 )
Brief. Bioinformatics - New developments of alignment-free sequence comparison: measures, statistics and next-generation sequencing. ( 24 )
Brief. Bioinformatics - Comparative genomics approach to detecting split-coding regions in a low-coverage genome: lessons from the chimaera Callorhinchus milii (Holocephali, Chondrichthyes). ( 24 )
Curr Protoc Bioinformatics - Comparative Protein Structure Modeling Using MODELLER. ( 24 )
J Chem Inf Model - Protein structural statistics with PSS. ( 24 )
Brief. Bioinformatics - Systematic identification of Class I HDAC substrates. ( 23 )
Comput Biol Chem - Large replication skew domains delimit GC-poor gene deserts in human. ( 23 )
J Chem Inf Model - Tertiary structure prediction of RNA-RNA complexes using a secondary structure and fragment-based method. ( 23 )
J Chem Inf Model - Data-driven high-throughput prediction of the 3-D structure of small molecules: review and progress. ( 23 )
Med Biol Eng Comput - The influence of alignment-free sequence representations on the semi-supervised classification of class C G protein-coupled receptors: semi-supervised classification of class C GPCRs. ( 23 )
Comput Biol Chem - A novel empirical mutual information approach to identify co-evolving amino acid positions of influenza A viruses. ( 22 )
Comput Biol Chem - Tri-peptide reference structures for the calculation of relative solvent accessible surface area in protein amino acid residues. ( 22 )
Comput Biol Chem - A protein fold classifier formed by fusing different modes of pseudo amino acid composition via PSSM. ( 22 )
Comput Biol Chem - Relationship between global structural parameters and Enzyme Commission hierarchy: implications for function prediction. ( 22 )
Brief. Bioinformatics - The UCSC genome browser and associated tools. ( 22 )
Healthc (Amst) - What can the past of pay-for-performance tell us about the future of Value-Based Purchasing in Medicare? ( 22 )
Comput. Biol. Med. - Remote homology detection incorporating the context of physicochemical properties. ( 22 )
Comput. Biol. Med. - Remote protein homology detection and fold recognition using two-layer support vector machine classifiers. ( 22 )
J Am Med Inform Assoc - HUGO: Hierarchical mUlti-reference Genome cOmpression for aligned reads. ( 22 )
J Chem Inf Model - Molecular determinants of Bim(BH3) peptide binding to pro-survival proteins. ( 22 )
J Chem Inf Model - ProBiS-database: precalculated binding site similarities and local pairwise alignments of PDB structures. ( 22 )
Comput Biol Chem - In silico characterization and evolutionary analyses of CCAAT binding proteins in the lycophyte plant Selaginella moellendorffii genome: a growing comparative genomics resource. ( 21 )
Comput Biol Chem - Gene cloning, homology comparison and analysis of the main functional structure domains of beta estrogen receptor in Jining Gray goat. ( 21 )
Brief. Bioinformatics - Identify drug repurposing candidates by mining the protein data bank. ( 21 )
Comput Math Methods Med - Quad-PRE: a hybrid method to predict protein quaternary structure attributes. ( 21 )
J Chem Inf Model - 3D flexible alignment using 2D maximum common substructure: dependence of prediction accuracy on target-reference chemical similarity. ( 21 )
J Chem Inf Model - Dihedral-based segment identification and classification of biopolymers II: polynucleotides. ( 21 )
J. Comput. Biol. - Evaluating, comparing, and interpreting protein domain hierarchies. ( 21 )
J. Comput. Biol. - IDBA-MTP: A Hybrid Metatranscriptomic Assembler Based on Protein Information. ( 21 )
J. Comput. Biol. - Emergent protein folding modeled with evolved neural cellular automata using the 3D HP model. ( 21 )
J. Comput. Biol. - Computational techniques for human genome resequencing using mated gapped reads. ( 21 )
Comput Biol Chem - Computational insight into nitration of human myoglobin. ( 20 )
Comput Biol Chem - Probabilistic model based error correction in a set of various mutant sequences analyzed by next-generation sequencing. ( 20 )
Comput Biol Chem - Multi-nucleation and vectorial folding pathways of large helix protein. ( 20 )
Artif Intell Med - Predicting malaria interactome classifications from time-course transcriptomic data along the intraerythrocytic developmental cycle. ( 20 )
Comput Biol Chem - Bacterial genomes lacking long-range correlations may not be modeled by low-order Markov chains: the role of mixing statistics and frame shift of neighboring genes. ( 20 )
Comput Biol Chem - Identification of potential drug targets by subtractive genome analysis of Bacillus anthracis A0248: An in silico approach. ( 20 )
Brief. Bioinformatics - Ultrafast clustering algorithms for metagenomic sequence analysis. ( 20 )
Comput Methods Programs Biomed - Discriminating protein structure classes by incorporating Pseudo Average Chemical Shift to Chou's general PseAAC and Support Vector Machine. ( 20 )
Comput. Biol. Med. - A protein mapping method based on physicochemical properties and dimension reduction. ( 20 )
J Chem Inf Model - Critical residue that promotes protein dimerization: a story of partially exposed Phe25 in 14-3-3s. ( 20 )
J. Comput. Biol. - CNVeM: copy number variation detection using uncertainty of read mapping. ( 20 )
Comput Biol Chem - Overlapping genetic codes for overlapping frameshifted genes in Testudines, and Lepidochelys olivacea as special case. ( 19 )
Comput Biol Chem - Global expression analysis of miRNA gene cluster and family based on isomiRs from deep sequencing data. ( 19 )
Brief. Bioinformatics - Automated glycopeptide analysis--review of current state and future directions. ( 19 )
Comput Biol Chem - Analysis of the relationships between evolvability, thermodynamics, and the functions of intrinsically disordered proteins/regions. ( 19 )
Brief. Bioinformatics - Sequencing technologies and tools for short tandem repeat variation detection. ( 19 )
Comput Math Methods Med - Uses of phage display in agriculture: sequence analysis and comparative modeling of late embryogenesis abundant client proteins suggest protein-nucleic acid binding functionality. ( 19 )
Comput Methods Programs Biomed - Protein secondary structure prediction using modular reciprocal bidirectional recurrent neural networks. ( 19 )
Comput. Biol. Med. - miRClassify: an advanced web server for miRNA family classification and annotation. ( 19 )
Int J Health Geogr - Linking GPS and travel diary data using sequence alignment in a study of children's independent mobility. ( 19 )
J Chem Inf Model - Improved helix and kink characterization in membrane proteins allows evaluation of kink sequence predictors. ( 19 )